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Other Targets lists biosimilar antibodies whose targets fall outside the main groups or have few products. Examples include omalizumab and ligelizumab, which bind immunoglobulin E (IgE), and bimagrumab, which blocks activin type II receptors. Lirilumab targets killer-cell immunoglobulin-like receptors (KIRs) on natural killer cells. The group also includes antibodies to allergens, Wnt pathway receptors, proteases, transporters and intracellular proteins such as histones. Several fusion proteins and peptide conjugates are listed here as well, including the long-acting granulocyte colony-stimulating factor (G-CSF) analogs balugrastim and eflapegrastim.
The Anti-Glycophorin A (type M) Antibody (6A7M) is a chimeric mouse monoclonal antibody of the IgG1, κ isotype, specifically designed to target human Glycophorin A (type M). For optimal use in experimental controls, it is recommended to utilize the Mouse IgG1 kappa Isotype Control.
Freneslerbart is an IgG4κ monoclonal antibody specifically designed to target Felcat allergen 1, a known allergenic protein. This antibody's high specificity makes it an invaluable tool for the study and identification of Felcat allergen 1 in various research applications, including allergenicity studies and environmental monitoring of allergens.
The Anti-CYR61/CCN1 Antibody is a recombinant human monoclonal antibody produced in CHO cells, designed to specifically target CYR61/CCN1, a key regulatory protein involved in cellular processes such as proliferation, angiogenesis, and wound healing. This antibody is composed of a human IgG1 heavy chain and a human kappa light chain, with an approximate molecular weight of 150 kDa. For experimental control purposes, the Human IgG1 kappa, Isotype Control is recommended as the appropriate isotype control for this antibody. This product is ideal for researchers studying cellular signaling pathways influenced by CYR61/CCN1 in various biological contexts.
Zaltenibart is a chimeric humanized antibody of the IgG4κ subtype that specifically targets MASP3. For experimental control purposes, it is recommended to use Human IgG4 (S228P) kappa as the isotype control. This specificity and design make Zaltenibart suitable for detailed immunological research and therapeutic investigations related to the MASP3 pathway.
The Anti-GOLM1 Antibody is a human monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically designed to target GOLM1 (Golgi Membrane Protein 1). This antibody is composed of a human IgG1 heavy chain and a human kappa light chain, with an estimated molecular weight of 150 kDa. For isotype control purposes, the Human IgG1 kappa, Isotype Control is recommended. This product is essential for researchers focusing on cellular and molecular studies involving the Golgi apparatus and related protein functions.
The Anti-MST1R Antibody (MOR07692) is a humanized IgG1 monoclonal antibody specifically designed to target MST1R, a receptor tyrosine kinase implicated in various cellular processes and oncogenic pathways. For accurate experimental control, it is recommended to use Human IgG1 kappa as an isotype control. This antibody is suitable for a range of research applications, ensuring specificity and reliability in targeting MST1R for detailed biological analysis and potential therapeutic investigation.
Anti-IL-13Ra2/CD213a2 is a recombinant human monoclonal antibody produced in Chinese hamster ovary (CHO) cells, specifically designed to target IL-13Ra2/CD213a2. This antibody exhibits a molecular weight of approximately 150 kDa. For isotype control purposes, Human IgG1 kappa, Isotype Control is recommended. This product is ideal for use in research applications focusing on the biological pathways and disease associations linked to IL-13Ra2/CD213a2.
Synonyms: SARS-CoV-2 (2019-nCoV Single-Domain Antibodies; Humanized Single Domain Antibody
The Anti-Spike-RBD Single Domain mAb is a recombinant alpaca monoclonal VHH-huFc antibody produced in CHO cells. This antibody exhibits high affinity and specific binding to the receptor-binding domain (RBD) of SARS-CoV-2. Its unique single-domain architecture and human Fc fusion enhance both stability and detection capabilities, making it an ideal tool for research applications focused on COVID-19 and related coronavirus studies.
Synonyms: 16B5; AB-16B5
Sotevtamab (16B5) is a humanized IgG2 monoclonal antibody specifically targeting clusterin. It acts as an inhibitor of the epithelial to mesenchymal transition (EMT), a process critical in the development and progression of cancer. This antibody is particularly useful in cancer research, providing a valuable tool for studying the role of clusterin in tumor dynamics and potential therapeutic interventions.
Synonyms: 5F9 Monoclonal antibody
Indusatumab, designated as 5F9, is a monoclonal antibody specifically targeting human Guanylate Cyclase 2C (GUCY2C). This antibody is developed for high specificity and affinity, making it an essential tool for research into GUCY2C's role in cellular signaling and potential implications in gastrointestinal diseases and cancers.
The Anti-CD69 Antibody is a human-derived monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically targeting the CD69 molecule. This antibody has a predicted molecular weight of 150 kDa. For isotype control purposes, Human IgG1 kappa, Isotype Control is recommended. This product is essential for research focused on the activation and regulation of T and B lymphocytes, as CD69 is an early activation marker in these cell types.
The Anti-MICB Antibody is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells. It specifically targets the MHC class I polypeptide-related sequence B (MICB), a stress-induced ligand involved in immune recognition by natural killer (NK) cells and certain T cells. This antibody is composed of a human IgG2 heavy chain and a human kappa light chain, with an approximate molecular weight of 143.66 kDa. For experimental control purposes, Human IgG2 kappa, Isotype Control is recommended.
The Anti-BRCA1 Antibody (BR64) is a chimeric mouse monoclonal antibody of the IgG1, κ subclass, specifically designed to target human BRCA1. For accurate experimental control, it is recommended to use Mouse IgG1 kappa Isotype Control alongside this antibody.
The Anti-CD71 Antibody (OKT-9) is a chimeric mouse monoclonal antibody of the IgG1κ subclass, specifically designed to target human CD71. For accurate experimental control, it is recommended to use Mouse IgG1 kappa as an isotype control. This antibody is essential for studies focusing on the CD71 transmembrane protein, commonly known as the transferrin receptor, which plays a crucial role in iron uptake and cellular proliferation.
The Anti-c-Myc Antibody (9E10) is a chimeric mouse monoclonal antibody of the IgG1 subtype, specifically designed to target the human c-Myc protein. For accurate isotype control in experimental setups, it is recommended to use Mouse IgG1 kappa Isotype Control. This antibody is ideal for research applications focusing on cellular processes involving the c-Myc protein.
Synonyms: MM-302
Gancotamab (MM-302) is a conjugate of a HER2-targeted antibody and liposomal Doxorubicin, designed to enhance the delivery of Doxorubicin directly to tumor cells expressing high levels of HER2. This formulation capitalizes on the specificity of monoclonal antibodies for HER2 to selectively target and exert antitumor activity, thereby potentially improving therapeutic efficacy and reducing systemic toxicity. Gancotamab is primarily utilized in research focused on the treatment of HER2-positive cancers.
The Anti-CLEC7A Antibody is a humanized monoclonal antibody produced in Chinese hamster ovary (CHO) cells, specifically designed to target CLEC7A (C-type lectin domain family 7 member A). This antibody has a predicted molecular weight of 150 kDa. For isotype control, it is recommended to use Human IgG4 kappa, Isotype Control, which serves as a standard in experiments to help distinguish specific from non-specific binding. This product is essential for researchers focusing on the role of CLEC7A in immune response and its implications in various inflammatory and infectious diseases.
Synonyms: 2D10
Vapaliximab (2D10) is a monoclonal antibody specifically designed to target and bind to human vascular adhesion protein-1 (VAP-1). This antibody is utilized primarily in research focused on inflammatory processes and vascular biology, providing insights into the role of VAP-1 in disease mechanisms and potential therapeutic interventions.
Efpegsomatropin is a conjugate composed of human growth hormone linked to an Fc peptide, designed to enhance molecular stability and extend serum half-life. This conjugate is ideal for use in a range of biochemical studies, including investigations into growth hormone signaling pathways and the pharmacokinetics of peptide hormones. Its unique structure makes it a valuable tool for researchers studying the regulation of growth and metabolism.
REGN5054 is a fully human monoclonal IgG1 antibody designed to bind specifically to CD8 antigens expressed on T cells in both human and cynomolgus models. This antibody provides a valuable tool for the study of T-cell function and the role of CD8 in immune responses.
Mibavademab is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically targeting LEPR/CD295. This antibody is comprised of a human IgG4SP heavy chain and a human kappa light chain, exhibiting a predicted molecular weight of 145.58 kDa. For experimental control purposes, the appropriate isotype control is Human IgG4 kappa.
Synonyms: UCB-7858
Zampilimab (UCB-7858) is a monoclonal antibody specifically targeting transglutaminase 2 (TG2). This antibody demonstrates potential utility in enhancing the outcomes of renal transplantation. Zampilimab has been developed to modulate immune responses, potentially reducing the risk of transplant rejection and improving graft survival. Its precise mechanism involves the inhibition of TG2, an enzyme implicated in inflammation and tissue fibrosis. This product is pivotal for research focused on transplant immunology and the development of therapeutic strategies to increase transplant success rates.
