HLI 373

Catalog No.: A15347

HDM2 inhibitor

HLI 373 Chemical Structure

CAS NO. 502137-98-6

HLI 373 is an inhibitor of Hdm2 ubiquitin ligase (E3) which blocks Hdm2-mediated ubiquitylation, proteasomal degradation of p53 and activates p53-dependent transcription.

Availability: Out of stock

Package Price
10 mg

Regular Price: $115.00

Special Price $92.00

50 mg

Regular Price: $495.00

Special Price $396.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

HLI 373 is an inhibitor of Hdm2 ubiquitin ligase (E3) which blocks Hdm2-mediated ubiquitylation, proteasomal degradation of p53 and activates p53-dependent transcription.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.14 mL 120.68 mL 241.36 mL
0.5 mM 4.83 mL 24.14 mL 48.27 mL
1 mM 2.41 mL 12.07 mL 24.14 mL
5 mM 0.48 mL 2.41 mL 4.83 mL

*The above data is based on the productmolecular weight 414.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15347
Actions Inhibitor
M. Wt 414.32
Formula C18H23N5O2.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 502137-98-6
Synonyms N/A
SMILES CN1C2=CC=CC=C2C(=C3C1=NC(=O)N(C3=O)C)NCCCN(C)C.Cl.Cl

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