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Phospholipids, mainly glycerophospholipids, form cell membrane bilayers and give rise to lipid signaling mediators. Each glycerophospholipid carries fatty acyl or ether-linked chains on a glycerol backbone and a phosphate-containing head group. Egg phosphatidylcholines, a natural mixture of phosphatidylcholine species, are commonly used to prepare model membranes and vesicles. sn-Glycero-3-phosphocholine is the deacylated backbone of phosphatidylcholine and a water-soluble metabolite of choline metabolism. Oxidized phospholipids such as POVPC arise when polyunsaturated acyl chains in membranes and lipoproteins are oxidized. 2-O-Methyl PAF C-16 is an ether lipid analog of platelet-activating factor (PAF). A few compounds, such as the nucleotide 5-PA-dUTP, are phosphate-containing reagents rather than phospholipids.
N-Linoleoyl-DPPE ammonium is an N-acylphosphatidylethanolamine (NAPE) analog known for its bioactive properties. It plays a significant role in cellular signaling and is involved in the regulation of various physiological processes, including inflammation and pain modulation. This compound is utilized in research applications focusing on lipid biology, neurobiology, and the exploration of endocannabinoid systems.
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Synonyms: 1,2-NMeDPPE
16:0 Monomethyl PE (1,2-NMeDPPE) is an alkyl phosphate that primarily targets lipid membranes. This compound is utilized in various biological research applications, including studies of membrane dynamics and lipid interactions. Its unique structure allows for examination of lipid-based signaling pathways and cellular processes involving phospholipids.
Synonyms: 1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium
16:0 Lyso PS, or 1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium, is a lysophospholipid that functions as a critical standard for the preparation of standard curves in analytical assays. This compound is utilized in various biological applications, including the study of lipid metabolism and signaling pathways. Its role as a calibration standard aids in the quantification and characterization of lysophospholipids in research settings.
Synonyms: PFDB
Perfluorodecyl bromide is a high molecular weight lipophilic fluorocarbon acting as a versatile building block for producing phospholipid-stabilized fluorocarbon emulsions. Its unique properties make it suitable for applications in biomedical research, particularly in enhancing oxygen delivery and serving as a contrast agent in imaging studies. This compound plays an important role in the development of innovative therapeutic and diagnostic strategies.
18:1 PE-Benzylguanine ammonium is a lipid that serves as a reactive substrate for SNAP-tag protein labeling. This compound facilitates the covalent attachment of proteins to lipid membranes, enabling the study of protein localization and dynamics in live cells. It is particularly useful in applications such as cellular imaging, protein tracking, and the investigation of lipid-protein interactions.
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4ME 16:0 PG sodium is a diphytanoyl lipid that serves as a lipid molecular species used in various biochemical applications. This compound exhibits significant potential in the study of lipid metabolism and membrane dynamics. Researchers can utilize 4ME 16:0 PG sodium to explore its role in cellular processes and its impact on lipid-related signaling pathways.
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18:1-12:0 Biotin PS ammonium is a biotinylated phosphatidylserine (PS) lipid. This compound serves as a versatile tool for studying lipid-protein interactions and cellular membrane dynamics. Its biotinylation allows for easy tagging and identification in various biological assays, making it suitable for applications in cell imaging and lipid-based experiments.
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Synonyms: 1,2-Di-O-octadecyl-sn-glycero-3-phosphocholine
18:0 Diether PC, or 1,2-Di-O-octadecyl-sn-glycero-3-phosphocholine, is a glycerophospholipid that functions as a non-hydrolyzable ether lipid. It stabilizes calcein-containing vesicles, making it a valuable tool in membrane biophysics and lipid metabolism studies. This compound is essential for research into membrane structure and dynamics, as well as drug delivery applications.
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DSPE-RGD Lipid sodium is a lipid compound that incorporates DSPE and RGD peptides, targeting integrin receptors for enhanced cellular uptake. This reagent facilitates the formation of lipid nanoparticles, which are instrumental in the delivery of therapeutic agents. Its ability to promote targeted drug delivery makes it a valuable tool in pharmaceutical research and development.
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16:0 Phosphatidylethanol sodium is a phospholipid that acts as a key component of cellular membranes. This alkyl phosphate plays a crucial role in lipid signaling and membrane dynamics. It is widely utilized in research applications related to membrane biology, cell signaling pathways, and the study of lipid interactions in various biological systems.
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4ME 16:0 PA sodium is a diphytanoyl lipid that primarily targets cellular membrane structures. This compound plays a crucial role in lipid metabolism and can be utilized in studies related to membrane dynamics and lipid signaling pathways. Its unique biochemical properties make it valuable for research applications in cellular biology and biochemistry.
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16:0-17:0 Cyclo PC is a cyclopropyl lipid with unique structural properties. It functions primarily as a phospholipid, impacting membrane fluidity and cellular signaling pathways. This compound is valuable in lipid research and can be utilized in studies focusing on membrane dynamics, lipid interactions, and the role of phospholipids in cellular processes.
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18:1 DGPP ammonium is a diacylglycerol pyrophosphate (DGPP) that serves as a key signaling lipid. It plays a crucial role in various cellular processes, including membrane dynamics and signal transduction. This compound is valuable for research on lipid metabolism, cellular signaling pathways, and the study of membrane-associated proteins.
Synonyms: 1-Octanoyl-sn-glycero-3-phosphocholine
08:0 Lyso PC (1-Octanoyl-sn-glycero-3-phosphocholine) is a lysolecithin that serves as a substrate for Phospholipase A2 enzymatic activity. This compound is utilized in studies focusing on lipid metabolism and membrane dynamics, as well as investigations into inflammatory processes. Its hydrolysis by Phospholipase A2 makes it valuable for research into signaling pathways and cell membrane composition.
18:1(n10)-16:0 PC - IsoPure is an isomerically pure mixed-acyl glycerophospholipid that targets lipid metabolism. This compound exhibits essential biological activity in membrane dynamics and cellular signaling. It is widely utilized in lipid research, including studies on membrane structure, function, and the role of phospholipids in various biological processes.
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Synonyms: 1,2-Didodecanoyl-sn-glycero-3-phospho-(1′racglycerol) sodium
1,2-Dilauroyl-sn-glycero-3-PG sodium is a phospholipid characterized by its 12:0 fatty acid composition. This compound demonstrates excellent surfactant properties, making it valuable in various biochemical applications. It is ideally suited for studies related to membrane biology, drug delivery systems, and the formulation of liposomes in pharmaceutical research.
18:1 Propargyl PC is a clickable phospholipid that serves as a versatile lipid for various biochemical applications. This compound enables the study of lipid interactions, membrane dynamics, and cellular processes through its unique alkyne functionality. It is particularly useful in click chemistry reactions for tagging and imaging studies in cellular biology. Researchers can utilize 18:1 Propargyl PC to investigate lipid behavior in model membranes or in live cells, providing insights into membrane composition and function.
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18:0 PE-Square sodium is a functionalized phospholipid targeting lipid bilayers in cellular membranes. This compound plays a crucial role in membrane structuring and the study of lipid interactions and dynamics. It is widely used in membrane biophysics research, drug delivery systems, and the development of liposome formulations.
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Synonyms: 1,2-Dipalmitoyl-sn-glycero-3-phosphomethanol sodium
16:0 Phosphatidylmethanol sodium is a phosphatidyl alcohol featuring methanol head groups. This compound is primarily utilized in membrane biophysics and cell biology studies, serving as a model for phospholipid behavior. Its unique structure allows for investigations into membrane dynamics, lipid-protein interactions, and cellular signaling processes.
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16:0-20:4 PE-N-20:4 ammonium is an anandamide class lipid that serves as a bioactive signaling molecule. It is involved in various biological processes including cell signaling and neuroprotection. This compound is valuable for research applications focused on lipid metabolism, endocannabinoid signaling, and the modulation of inflammatory responses.
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16:0 PE-DTPA (Gd) is a lipid-based MRI imaging reagent utilizing Gadolinium as a contrast agent. This compound effectively enhances the contrast in magnetic resonance imaging applications, facilitating the visualization of biological tissues. It is particularly useful in research related to biomedical imaging and diagnostic applications, providing valuable insights into cellular and molecular processes.
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18:1(n9)-16:0 PE - IsoPure is an isomerically pure mixed-acyl glycerophospholipid that serves as a model lipid for studying membrane dynamics and cellular signaling. This compound plays a crucial role in membrane composition, influencing lipid bilayer properties and fluidity. Its applications extend to research involving lipid metabolism and the investigation of membrane-associated proteins.
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18:1 Aminoethyl phosphatidylcholine (PC) is a functionalized lipid that serves as a critical component in cell membrane modeling and membrane fusion studies. It exhibits properties conducive to the formation of lipid bilayers and is utilized in the development of liposomes for drug delivery applications. Its unique structure allows for enhanced interaction with biomolecules, making it an essential reagent for membrane biophysics and cellular biology research.
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Bis(14:0 PE)-DTPA (Gd) diammonium is a gadolinium-based MRI contrast agent. This compound acts as a lipid-targeting reagent, enhancing the visibility of tissues during magnetic resonance imaging. It is utilized in research applications focused on the development of imaging modalities and the study of lipid-associated structures in biological systems.
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Synonyms: 1,2-Diarachidonoyl-sn-glycero-3-[phospho-rac-(1-glycerol)] sodium
20:4 PG sodium, also known as 1,2-Diarachidonoyl-sn-glycero-3-[phospho-rac-(1-glycerol)], is a glycerophospholipid that serves as a potent oxidized phospholipid. This compound plays a crucial role in biological processes such as cell signaling and inflammation. It is valuable in research applications exploring lipid metabolism, membrane biology, and the interactions of oxidized lipids with cellular pathways.
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