Phospholipids

Cat. No.

A76129

CAS No.

185435-28-3

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol

Synonyms: POPG

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) targets anionic phosphatidylglycerols and is crucial for constructing model phospholipid bilayers, often in conjunction with phosphatidylcholine. This compound plays a significant role in studying the structure and dynamics of transmembrane proteins, thereby facilitating research into membrane protein interaction mechanisms. Its use in mimicking biological membrane properties enhances the understanding of membrane biology and related processes.

Cat. No.

A76159

CAS No.

63988-20-5

Tetramyristoylcardiolipin diammonium

Synonyms: TMCL diammonium

Tetramyristoylcardiolipin diammonium is an anionic lipid that serves as a crucial component in the investigation of cell membrane dynamics and function. This compound plays a significant role in enhancing drug delivery systems by facilitating membrane interactions. Its unique properties make it a valuable reagent for research focused on lipid biochemistry and cellular processes.

Cat. No.

A76161

CAS No.

18656-38-7

1,2-DImyristoyl-rac-glycero-3-phosphocholine

1,2-Dimyristoyl-rac-glycero-3-phosphocholine (DMPC) is a zwitterionic phospholipid that serves as an effective model for eukaryotic cell membranes. It mimics the neutral charge characteristic of eukaryotic plasma membranes, making it suitable for studying membrane dynamics and interactions. DMPC is widely used in biophysical and biochemical research, providing insights into membrane fluidity, protein-lipid interactions, and lipid organization.

Cat. No.

A76162

CAS No.

5634-86-6

1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine

Synonyms: DAPE

1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine (DAPE) is a phospholipid derivative of phosphatidylethanolamine. DAPE does not significantly affect protein phosphatase PP2A activity or inhibit insulin-stimulated GLUT4 translocation, distinguishing it from other phosphatidylethanolamines. This unique profile makes DAPE a valuable tool for research in lipid signaling and metabolic functions, facilitating the study of cellular processes related to insulin sensitivity and lipid metabolism.

Cat. No.

A76171

CAS No.

61596-53-0

1,2-Diarachidoyl-sn-glycero-3-phosphocholine

Synonyms: Phosphatidylcholine Diarachidoyl; 1,2-DAPC; L-α-Diarachidonoyl lecithin

1,2-Diarachidoyl-sn-glycero-3-phosphocholine (1,2-DAPC) is a phospholipid characterized by the presence of saturated long-chain arachidic acid at both the sn-1 and sn-2 positions. This compound is instrumental in the formation of micelles, liposomes, and various artificial membranes, making it valuable in studies related to membrane biophysics and drug delivery systems. Its unique properties facilitate the exploration of lipid behavior and interactions in biological systems.

Cat. No.

A76197

CAS No.

111516-02-0

18:1 Glutaryl PE monosodium

Synonyms: DOPE-GA monosodium

18:1 Glutaryl PE monosodium is a functionalized lipid that serves as a phospholipid precursor. It exhibits key properties for lipid membrane modeling and can be utilized in the study of cellular membrane dynamics and interactions. This compound is particularly valuable in research applications related to drug delivery systems and lipid bilayer formulation.

Cat. No.

A76203

CAS No.

26662-91-9

(Rac)-POPC

(Rac)-POPC is a model phosphatidylcholine that serves as a key component for the preparation of giant vesicles (GVs). It plays a crucial role in membrane studies and biophysical research by providing insights into lipid bilayer properties and membrane dynamics. This reagent is ideal for applications in membrane biophysics, drug delivery research, and investigations into lipid-based cellular processes.

Cat. No.

A76213

CAS No.

62700-69-0

DOPG

Synonyms: Dioleoylphosphatidylglycerol

Dioleoylphosphatidylglycerol (DOPG) is a negatively charged phosphatidylglycerol phospholipid known for its significant presence in prokaryotic cell membranes and mitochondria. It exhibits a low phase transition temperature, allowing for the formation of stable vesicles. DOPG plays a crucial role in inhibiting inflammatory mediators in macrophages activated via heat shock protein B4 (HSPB4) and toll-like receptor 2 (TLR2). This reagent is essential for studies in membrane biology, drug-membrane interactions—particularly with negatively charged membranes—and the development of drug delivery systems, as well as investigations into sterile corneal inflammation and wound healing.

Cat. No.

A76217

CAS No.

217939-97-4

1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol

Synonyms: DSPG

1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is an anionic phospholipid that plays a pivotal role in membrane dynamics and cellular interactions. This compound is commonly employed in drug delivery systems and the formulation of liposomes, facilitating the encapsulation and targeted transport of therapeutic agents. Its properties make it a valuable tool in various biomedical research applications, particularly in the fields of drug development and nanomedicine.

Cat. No.

A76237

CAS No.

144735-79-5

DSPE-SPDP

DSPE-SPDP is a phospholipid molecule that facilitates the formation of lipid bilayers in aqueous environments, mimicking biological membranes. This compound is instrumental in various biochemical research applications, particularly in the study of membrane dynamics, drug delivery systems, and the characterization of liposomal formulations. Its structural properties make it a valuable reagent for investigations into lipid-based nanocarriers and molecular interactions within lipid environments.

Cat. No.

A76282

CAS No.

6542-05-8

1,2-Dilinoleoyl-sn-glycero-3-PC

Synonyms: Dilinoleoyllecithin

1,2-Dilinoleoyl-sn-glycero-3-PC is a phospholipid known for its role in forming lipid bilayers. It exhibits key properties that make it suitable for the construction of artificial membranes, allowing for the study of membrane dynamics and functionality. This compound is often utilized in research applications involving drug delivery systems and membrane protein studies.

Cat. No.

A76285

CAS No.

2389048-58-0

DOPE PEG(2000)-N-Cyanine 5

DOPE PEG(2000)-N-Cyanine 5 is a phospholipid that serves as an amphiphilic compound, enhancing biocompatibility in various research applications. This reagent plays a crucial role in drug delivery systems, facilitating improved formulation and therapeutic efficacy. Its unique properties make it suitable for investigating lipid-based drug delivery mechanisms and the development of innovative therapeutic strategies.

Cat. No.

A76293

CAS No.

81490-05-3

Palmitoyloleoylphosphatidylglycerol

Palmitoyloleoylphosphatidylglycerol is an anionic surfactant lipid with notable effects on inflammatory signaling. This compound effectively suppresses Der p 2-stimulated inflammatory responses in lung epithelial cells and macrophages, making it valuable for research into respiratory inflammation and related disorders. Its unique properties facilitate studies on lipid interactions and their implications in cellular responses.

Cat. No.

A76342

CAS No.

163751-35-7

rac-3-Hexadecanamido-2-methoxypropan-1-ol phosphocholine hydrate

Rac-3-Hexadecanamido-2-methoxypropan-1-ol phosphocholine hydrate is a phospholipid compound that acts as an inhibitor of Protein Kinase C. This reagent is pertinent for studies investigating lipid signaling pathways and cellular processes influenced by kinase activity. Its role in modulating protein interactions makes it significant for research in cellular signaling and membrane biochemistry.

Cat. No.

A76343

CAS No.

474944-16-6

16:0 PDP PE

16:0 PDP PE is a head group modified functionalized lipid that serves as an important component in lipid-based research. This reagent is utilized in the synthesis of rhodamine high-density lipoprotein nanoparticles (Rh-HDL NP), facilitating studies in lipid metabolism and delivery systems. Its unique structural properties enable the exploration of lipid interactions and applications in drug delivery and nanotechnology.

Cat. No.

A76353

CAS No.

2260669-34-7

Cardiolipin (16:1/16:1/16:1/16:1) sodium salt

Synonyms: Diphosphatidylglycerol sodium salt; 16:1 Cardiolipin sodium salt; 64:4-CL sodium salt

Cardiolipin (16:1/16:1/16:1/16:1) sodium salt is an anionic phospholipid that facilitates hydroxyapatite crystallization and enhances supersaturation in calcium solutions. Its unique structural properties make it a valuable reagent for studying membrane dynamics and mitochondrial function. This compound is essential in various research applications, including biomineralization, cellular bioenergetics, and the exploration of phospholipid interactions in biological systems.

Cat. No.

A76362

CAS No.

10389-08-9

Phosphoethanolamine calcium

Synonyms: Monoaminoethyl phosphate calcium; NSC 254167 calcium; O-Phosphoethanolamine calcium

Phosphoethanolamine calcium serves as a precursor for phosphatidylethanolamine and plays a critical role in the synthesis of phosphatidylcholine. This compound is important for investigating phospholipid metabolism and understanding cell membrane structure. Its application in biochemical studies can provide insights into cellular processes and lipid interactions.

Cat. No.

A76363

CAS No.

326495-23-2

1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium)

Synonyms: 18:0 Lyso PG sodium

1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium) acts primarily on phospholipid membranes. This lysophospholipid, featuring stearic acid at the sn-1 position, is essential for the formation of micelles, liposomes, and synthetic membranes. Its applications include the development of lipid-based drug delivery systems and studies involving membrane biophysics.

Cat. No.

A76381

CAS No.

6753-56-6

(Rac)-SOPC

Synonyms: (Rac)-PC(18:0/18:1); (Rac)-2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine

(Rac)-SOPC, or racemic 2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine, acts as an asymmetrical phospholipid. With stearic acid (18:0) at the sn-1 position and oleic acid (18:1) at the sn-2 position, (Rac)-SOPC plays a critical role in stabilizing the outer segment membrane of frog photoreceptor cells. This compound is of particular interest in studies focusing on membrane dynamics and lipid bilayer properties in biological systems.

Cat. No.

A76396

CAS No.

108321-06-8

1,2-Dilauroyl-sn-glycero-3-phosphate sodium

Synonyms: 1,2-DLPA Sodium; (2R)-2,3-bis(dodecanoyloxy)propyl hydrogen phosphate sodium

1,2-Dilauroyl-sn-glycero-3-phosphate sodium is a phospholipid characterized by the incorporation of lauric acid at the sn-1 and sn-2 positions. This compound plays a critical role in the formation of micelles, liposomes, and various artificial membrane systems. It is widely utilized in research applications involving membrane dynamics, drug delivery, and cellular interaction studies.

Cat. No.

A76399

CAS No.

2342575-84-0

DOPE-PEG-Azide ammonium

DOPE-PEG-Azide ammonium is a lipid containing a polyethylene glycol (PEG) moiety that facilitates the formation of lipid nanoparticles (LNPs) for drug delivery applications. Its azide functional group enables efficient click chemistry, allowing for the conjugation of various therapeutic agents or targeting ligands. This compound is suitable for research focused on developing and optimizing LNP systems for enhanced delivery of nucleic acids, proteins, and other bioactive compounds.

Cat. No.

A76401

CAS No.

123060-40-2

1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine

Synonyms: 14:0 Lyso PE; 1-Myristoyl-2-hydroxy-sn-glycero-3-PE; 1-Tetradecanoyl-sn-glycero-3-phosphoethanolamine

1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine, also known as 14:0 Lyso PE, is a lysophospholipid that features a phosphoethanolamine headgroup and a myristoyl fatty acid tail. This compound plays a critical role in cell signaling, known to induce transient increases in intracellular calcium levels in PC12 cells. Research indicates that elevated serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are associated with malignant breast cancer, highlighting its potential as a biomarker in cancer research. Its free amine group also allows for functionalization through conjugation with NHS-active esters or carboxylic acids using coupling agents.

Cat. No.

A77244

CAS No.

182509-36-0

1,2-Dilinoleoyl phosphatidylinositol

1,2-Dilinoleoyl phosphatidylinositol serves as a substrate for Phosphatidylinositol-4-phosphate 5-kinase (PI4P5K) isoforms α, β, and γ. This phosphatidylinositol derivative is essential in studying PI4P5K activity in vitro, contributing to our understanding of signaling pathways involving phosphoinositides. Its application extends to research on lipid metabolism and membrane dynamics in cellular processes.

Cat. No.

A88071

CAS No.

97802-53-4

Hexadecenyl-2-hydroxy-sn-glycero-3-PC

Synonyms: C16(Plasm) LPC; Lysophosphatidylcholine 16:0p/0:0

Hexadecenyl-2-hydroxy-sn-glycero-3-PC (C16(Plasm) LPC) is a phosphatidylcholine compound that modulates the aggregation of α-synuclein. By prolonging the lag phase of α-syn aggregation, this reagent serves as a valuable tool in Parkinson's disease research, facilitating the study of molecular mechanisms underlying neurodegenerative processes. Its unique structural properties make it an important component for investigating cell membrane dynamics and lipid signaling pathways in a variety of biological contexts.

Cat. No.

A88434

CAS No.

384833-24-3

18:0-18:1 PA sodium

Synonyms: 1-Stearoyl-2-oleoyl-sn-glycero-3-phosphate sodium

18:0-18:1 PA sodium, also known as 1-Stearoyl-2-oleoyl-sn-glycero-3-phosphate sodium, is an anionic lipid that plays a crucial role in cellular processes. This compound can modulate membrane properties and is utilized in various biological studies, including investigations of lipid signaling pathways and membrane dynamics. Its applications extend to the formulation of liposomes and as a component in studies of lipid-protein interactions.