Phospholipids

Cat. No.

A76009

CAS No.

26662-95-3

1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE

Synonyms: 1-Palmitoyl-2-linoleoyl PE; (1-Palmitoyl, 2-linoleoyl)-phosphatidylethanolamine; (1-Palmitoyl, 2-linoleoyl)-phosphoethanolamine

1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE is a phospholipid that facilitates the incorporation of nucleic acids, including small RNA (sRNA), into target cells. This lipid enhances cellular uptake and delivery efficiency, making it valuable for gene delivery and therapeutic applications. Researchers utilize this reagent to explore lipid-mediated transfection and related cellular processes in various biological studies.

Cat. No.

A76010

CAS No.

321863-21-2

1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine sodium

Synonyms: 1,2-POPS; 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium; 1-Hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine sodium salt

1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid that features oleic (18:1) and palmitic acid (16:0) acyl chains. This compound is essential for the preparation of lipid-mixing vesicles, liposomes, and artificial membranes, contributing significantly to research in membrane biology and drug delivery systems. Its unique structure allows it to facilitate studies on lipid interactions and biophysical properties of membranes.

Cat. No.

A76012

CAS No.

125401-63-0

1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate

1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate is a lipid that serves as a key element in the synthesis of phospholipid vesicles. This compound assists in achieving uniform vesicle sizes through freeze-thaw and extrusion methods, thereby facilitating enhanced protein encapsulation efficiency. Its unique properties make it valuable for applications in drug delivery systems and various biochemical studies.

Cat. No.

A76024

CAS No.

2839508-98-2

DSPE-N3

DSPE-N3 is a lipid that serves as a versatile click chemistry reagent featuring an azide group. It effectively participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. This compound is particularly valuable in biochemical research for applications such as biomolecule labeling, drug delivery, and the development of novel therapeutics.

Cat. No.

A76026

CAS No.

1010188-79-0

DOPE-NHS

DOPE-NHS is a lipid-based linker designed for the conjugation of peptides to exosomes and other membrane-associated nanoparticles. This reagent facilitates efficient drug delivery systems by enabling the stable attachment of cargo to lipid membranes. Its versatility supports various applications in targeted therapeutics and cellular engineering research.

Cat. No.

A76032

CAS No.

99296-81-8

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that incorporates into lipid monolayers and small unilamellar vesicles. This compound is utilized in the formulation of endoplasmic reticulum-targeted liposomes (PERLs), when combined in a specific molar ratio with other phospholipids. Research indicates that PERLs can significantly diminish cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and suppress HIV-1 particle secretion from HIV-1-infected PBMCs, making it valuable for studies in cellular metabolism and viral research.

Cat. No.

A76039

CAS No.

474922-90-2

18:1 PEG2000 PE ammonium

Synonyms: DOPE-PEG2000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium

18:1 PEG2000 PE ammonium is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate that targets neutral lipids. This compound exhibits significant potential for enhancing drug delivery systems by improving the solubility and stability of therapeutic agents. Its unique properties make it suitable for applications in biopharmaceutical research, particularly in the development of lipid-based delivery vectors.

Cat. No.

A76051

CAS No.

53862-35-4

1-Palmitoyl-2-hydroxy-sn-glycero-3-PE

1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid that serves as an immune response regulator. Produced by Microcystis aeruginosa under copper stress, this compound demonstrates the ability to alleviate toxicity. It is useful in research applications focused on immune modulation and the physiological effects of phospholipids in various biological contexts.

Cat. No.

A76056

CAS No.

474922-77-5

18:0 mPEG2000 PE ammonium

Synonyms: DSPE-mPEG2000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium

18:0 mPEG2000 PE ammonium is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate that serves as a PEG-phospholipid conjugate. It is primarily utilized in drug delivery applications, enhancing the solubility and stability of therapeutic molecules. This compound is instrumental in formulating nanoparticles and liposomes for targeted and efficient drug delivery in various biomedical research studies.

Cat. No.

A76059

CAS No.

70897-27-7

1,2-Diheptadecanoyl-sn-glycero-3-phosphorylcholine

Synonyms: DHPC

1,2-Diheptadecanoyl-sn-glycero-3-phosphorylcholine (DHPC) is a biologically active phospholipid compound derived from phosphatidylcholine (PC). It serves as an essential building block for the formation of micelles, liposomes, and various types of artificial membranes, making it valuable in membrane biology studies and drug delivery research. Its unique structure and properties facilitate investigations into membrane dynamics and cellular interactions.

Cat. No.

A76063

CAS No.

145849-32-7

12-Dipalmitoyl-sn-glycero-3-PS sodium salt

12-Dipalmitoyl-sn-glycero-3-PS sodium salt is an anionic phospholipid targeting cell membrane structures. It plays a crucial role as a lipid component, facilitating the formation of catanionic vesicles and liposomes. This reagent is widely used in biological research for membrane studies, drug delivery systems, and the development of nanocarriers.

Cat. No.

A76064

CAS No.

10015-88-0

1-Palmitoyl-2-oleoylphosphatidylethanolamine

Synonyms: POPE

1-Palmitoyl-2-oleoylphosphatidylethanolamine (POPE) is a synthetic phospholipid that primarily targets membrane bilayer formation. This PE-based compound exhibits the ability to intercalate with amphiphilic molecules, enabling the formation of stable lipid bilayers under physiological conditions. POPE is widely used in drug delivery research, facilitating the encapsulation and release of therapeutic agents for enhanced bioavailability and targeting efficiency.

Cat. No.

A76071

CAS No.

144735-82-0

DSPE-Thiol

DSPE-Thiol is a phospholipid modified with a thiol group, facilitating selective reactions with maleimide-containing compounds. This reagent is essential for the preparation of phospholipid dimers, enabling the study of membrane dynamics and lipid interactions. DSPE-Thiol is widely utilized in fields such as membrane biology, drug delivery systems, and the development of advanced bioconjugation techniques.

Cat. No.

A76073

CAS No.

326495-22-1

1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium)

Synonyms: 1-Palmitoyl-2-hydroxy-sn-glycero-3-PG sodium; 16:0 Lyso PG; PG(16:0/0:0); 1-Hexadecanoyl-sn-glycero-3-phospho-(1'racglycerol) (sodium)

1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium) is a lysophospholipid with palmitic acid (C16:0) at the sn-1 position, targeting phospholipid bilayers. Its primary biological activity includes the formation of micelles and liposomes, facilitating the development of artificial membranes. This reagent serves as a valuable tool in lipid-based drug delivery systems and various membrane studies in chemical research.

Cat. No.

A76084

CAS No.

6418-95-7

1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine

Synonyms: 1-Stearoyl-2-Oleoyl-sn-glycero-3-PE; 18:0-18:1 PE; PE(18:0/18:1)

1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine is a phospholipid featuring stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively. This compound plays a critical role in the formulation of lipid nanoparticles (LNPs), facilitating efficient in vitro delivery of mRNA and nuclear-targeted plasmid DNA. Its unique fatty acid composition enhances membrane fluidity and stability, making it invaluable in gene therapy and vaccine research applications.

Cat. No.

A76085

CAS No.

231615-77-3

18:1 DGS-NTA(Ni)

18:1 DGS-NTA(Ni) is a nickel-chelating lipid that exhibits a strong affinity for histidine-tagged proteins. Its ability to effectively bind to histidine tags makes it an invaluable tool for studies involving recombinant proteins. This compound is suitable for the preparation of liposomes and nanosized multilamellar vesicles (NMVs), facilitating research applications in protein and peptide binding studies, as well as antigen delivery systems.

Cat. No.

A76087

CAS No.

3436-44-0

1,2-Didecanoyl PC

Synonyms: 1,2-Didecanoyl-sn-glycero-3-phosphocholine

1,2-Didecanoyl PC (1,2-Didecanoyl-sn-glycero-3-phosphocholine) is a phosphocholine derivative that serves as a valuable model for studying saturated phospholipids in membrane dynamics. This compound is widely used in research applications involving single-chain mean field theory to estimate the free energy associated with the compressive or tensile properties of lipid bilayers in stack or multilayer configurations. The insights gained from these studies contribute to a better understanding of membrane behavior and interactions in biological systems.

Cat. No.

A76094

CAS No.

36314-47-3

1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine

Synonyms: 16:0 Diether PC

1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine is a synthetic ether-linked phospholipid that features hexadecyl chains at the sn-1 and sn-2 positions. This compound is instrumental in the formation of liposomes and artificial membranes, facilitating research into membrane dynamics and biophysical properties. Its unique structure supports studies on membrane permeability, interactions, and the development of drug delivery systems.

Cat. No.

A76096

CAS No.

6418-92-4

Glycerophosphoglycerol

Glycerophosphoglycerol is a key precursor in phospholipid biosynthesis. This compound plays a crucial role in supporting tumor cell membrane reconstruction and proliferation by enhancing phospholipid synthesis. Its potential applications make it valuable in research focused on breast cancer and related studies.

Cat. No.

A76103

CAS No.

322647-11-0

1-Stearoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine sodium

Synonyms: 18:0 -18:2 PS

1-Stearoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine sodium is a glycerophospholipid that primarily targets cell membrane dynamics and signaling pathways. This compound plays a crucial role in modulating lipid bilayer properties and is important in studies related to cell membrane integrity, lipid metabolism, and cellular signaling processes. It is commonly utilized in research applications involving membrane biophysics, neuroscience, and the development of drug delivery systems.

Cat. No.

A76111

CAS No.

20664-02-2

1-Stearoyl-2-myristoyl-sn-glycero-3-PC

Synonyms: 1S-2M-PC

1-Stearoyl-2-myristoyl-sn-glycero-3-PC (1S-2M-PC) is an asymmetric phospholipid integral to biological membranes. It exhibits distinct structural properties that influence membrane fluidity and protein interactions. This compound is valuable for research in membrane biology and lipid metabolism, facilitating studies on cellular signaling and membrane dynamics.

Cat. No.

A76115

CAS No.

1190099-61-6

L-DPPG

Synonyms: (R)-1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium

L-DPPG ((R)-1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium) is a phospholipid that targets biological membranes through its interaction with lipid bilayers via hydrophobic and electrostatic forces. This compound plays a critical role in the study of drug delivery systems, facilitating the encapsulation and release of therapeutic agents. Its properties make it an essential tool for researchers investigating membrane dynamics and the formulation of lipid-based drug carriers.

Cat. No.

A76116

CAS No.

156543-00-9

18:0 mPEG2000 PE

Synonyms: DSPE-mPEG2000; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

18:0 mPEG2000 PE is an amphiphilic polymer material that integrates a hydrophobic stearic acid chain (18:0) with hydrophilic polyethylene glycol (2000 Da). This combination facilitates the formation of stable liposomes and nanoparticles, thereby improving drug delivery efficiency, extending circulation time, and allowing for targeted delivery through functional terminal groups such as biotin or carboxyl. It is ideal for research applications involving nanoprobes and drug delivery systems.

Cat. No.

A76117

CAS No.

998-06-1

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine is a phospholipid that plays a critical role in cellular membrane structure and function. This compound has been utilized in obesity research to investigate lipid metabolism and its impact on energy homeostasis. Its unique fatty acid composition makes it a valuable tool for studying membrane fluidity and signaling pathways associated with metabolic disorders.

Cat. No.

A76121

CAS No.

56421-09-1

18:1(11-cis) PC

18:1(11-cis) PC is an unsaturated fatty acid characterized by 18 carbon atoms and a cis double bond at the 11th position. This compound plays a crucial role in regulating membrane fluidity, making it essential for various biochemical applications. It is commonly utilized in the synthesis of artificial liposomes for research in drug delivery and membrane biology.