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Phospholipids, mainly glycerophospholipids, form cell membrane bilayers and give rise to lipid signaling mediators. Each glycerophospholipid carries fatty acyl or ether-linked chains on a glycerol backbone and a phosphate-containing head group. Egg phosphatidylcholines, a natural mixture of phosphatidylcholine species, are commonly used to prepare model membranes and vesicles. sn-Glycero-3-phosphocholine is the deacylated backbone of phosphatidylcholine and a water-soluble metabolite of choline metabolism. Oxidized phospholipids such as POVPC arise when polyunsaturated acyl chains in membranes and lipoproteins are oxidized. 2-O-Methyl PAF C-16 is an ether lipid analog of platelet-activating factor (PAF). A few compounds, such as the nucleotide 5-PA-dUTP, are phosphate-containing reagents rather than phospholipids.
18:1 1,3-Cyclic LPA ammonium is a cyclic phosphatidic acid that serves as a key signaling lipid. It modulates various cellular processes, including cell proliferation, differentiation, and motility, through its interaction with lipid receptors. This reagent is utilized in research applications focused on lipid signaling pathways and their implications in various diseases.
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16:0 Hexynoyl PE ammonium is a clickable phospholipid that facilitates the study of lipid-related biological processes. Its unique chemical structure allows for specific labeling and tracking of lipid molecules in cellular systems. This reagent is particularly useful in lipidomic studies, drug delivery research, and the development of lipid-based therapeutic strategies.
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Synonyms: 1,2-Diundecanoyl-sn-glycero-3-phosphocholine
11:0 PC (1,2-Diundecanoyl-sn-glycero-3-phosphocholine) is a phosphatidylcholine that serves as a crucial component in membrane biology. It is involved in the proper folding and function of integral membrane proteins, thereby influencing membrane dynamics and protein functionality. This reagent is valuable for studies in biochemistry and molecular biology, particularly in the context of membrane protein research.
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18:1 PE-N-16:0 ammonium is a lipid compound that mainly acts as a phospholipid, playing a crucial role in membrane structure and function. It exhibits biological activity related to cell signaling and may influence various metabolic pathways. This compound is valuable in research applications involving lipid metabolism, cellular signaling, and the study of endocannabinoid systems.
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18:0-16:0(16-Azido) PC is a clickable phospholipid that incorporates an azide functional group, allowing for efficient conjugation reactions. This compound facilitates the study of lipid interactions and membrane dynamics in cellular environments. It is particularly useful in chemical biology research for applications such as lipid labeling, tracking, and the investigation of lipid-related biological processes.
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18:1-12:0 Biotin PA ammonium is a biotinylated derivative of phosphatidic acid designed for lipid research. Its ability to conjugate with streptavidin enhances applications in biochemistry and cell biology, facilitating the study of lipid-protein interactions. This reagent is particularly useful for experiments involving lipid metabolism, membrane biology, and signaling pathways.
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Synonyms: PtdIns-(4)-P1 (1,2-dioctanoyl) ammonium; 08:0 PI(4)P ammonium
1,2-Dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-4'-phosphate) ammonium targets phosphatidylinositol, a key component in cell signaling pathways. This synthetic phosphatidylinositol derivative is useful in the study of signal transduction processes and cellular functions. Its unique structure facilitates the exploration of inositol phosphate signaling pathways, making it a valuable tool for biochemical and pharmacological research.
18:1 Phosphatidylbutanol sodium is an alkyl phosphate that serves as a lipid signaling molecule. This compound plays a crucial role in cellular membrane dynamics and can influence various biological processes including cell proliferation and differentiation. It is commonly utilized in studies investigating lipid metabolism, membrane interactions, and signaling pathways related to phospholipid function.
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IKS02 is a phosphatidylcholine (PC) phospholipid that serves as a photoaffinity labeling probe. This compound facilitates the study of protein interactions and membrane dynamics by enabling the covalent attachment of biomolecules upon exposure to light. IKS02 is valuable in various research applications, including lipid-protein interaction studies and the characterization of membrane-associated proteins.
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a15:0-i15:0 PC is a branched phospholipid that plays a critical role in membrane formation and cellular signaling. Its unique structure contributes to the fluidity and stability of lipid bilayers, making it a valuable tool for studying lipid dynamics and membrane interactions. This compound is particularly useful in research applications focused on membrane biophysics, cell biology, and lipidomics.
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18:1-16:0 Phosphatidylethanol-IsoPure sodium is a mixed-acyl glycerophospholipid characterized by its isomeric purity. This compound serves as a critical component in lipid-based research, providing insights into membrane biophysics and cellular signaling pathways. Its unique acyl chain composition facilitates studies on lipid raft formation and membrane dynamics in various biological systems.
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16:0 DNP Cap PE monoammonium is an antigenic lipid that enhances the presentation of antigens on lipid bilayers, facilitating cellular immune responses. This compound is instrumental in studies focused on immunology, vaccine development, and the characterization of lipid-based delivery systems. Its ability to promote efficient antigen recognition makes it valuable in various research applications related to immune modulation and vaccine efficacy.
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16:0-18:0(4,5-Dibromo) Phosphatidylcholine is a brominated lipid that serves as a critical component in membrane studies and lipid signaling research. It is utilized to investigate lipid interactions and their influence on membrane dynamics and cellular processes. This reagent is valuable for exploring the effects of bromination on lipid behavior and can aid in the analysis of lipid-related diseases.
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16:0 Azidoethyl SM (d18:1/16:0) is a clickable phospholipid that incorporates an azide functional group, facilitating bioconjugation reactions. This compound is primarily utilized in lipid-related research and can be employed for labeling and tracking lipid molecules in biological systems. Its unique properties enable applications in studying membrane dynamics and cellular processes involving sphingolipids.
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16:0-18:1(n10) PC - IsoPure is an isomerically pure mixed-acyl glycerophospholipid that serves as a key component in lipid research. This phospholipid exhibits essential properties for studying membrane dynamics, cellular signaling, and lipid metabolism. Its high purity enhances experimental reproducibility and accuracy in various biological assays and applications.
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Synonyms: 1,2-Di-O-hexyl-sn-glycero-3-phosphocholine
06:0 Diether PC (1,2-Di-O-hexyl-sn-glycero-3-phosphocholine) is a glycerophospholipid that serves as a key component for the formation of bicelles. It plays a significant role in membrane model systems, facilitating the study of membrane protein interactions and dynamics. This compound is particularly useful in biophysical research applications, such as nuclear magnetic resonance (NMR) spectroscopy and other membrane-related investigations.
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Synonyms: N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine
Biotin-PE-maleimide is a sulfhydryl-reactive compound designed to facilitate biotin labeling of thiol-containing biomolecules. This membrane-impermeable reagent features a bulky structure that enhances specificity during labeling applications. It is ideally utilized for the detection and study of proteins and other biomolecules, enabling improved visualization in various biochemical assays.
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4ME 16:0 PS sodium is a diphytanoyl lipid that acts as a phosphatidylserine analog. It plays a crucial role in various cellular processes, including membrane dynamics and cell signaling. This reagent is applicable in studies investigating lipid metabolism, cell apoptosis, and neurobiology research. Its unique structure allows for in-depth exploration of lipid interactions within biological membranes.
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Synonyms: 18:1 Cyclic LPA
1-Oleoyl-sn-glycero-2,3-cyclic-phosphate ammonium, also known as Cyclic Phosphatidic Acid, serves as a crucial lipid molecule in cellular signaling. It demonstrates significant biological activity by modulating various cellular processes, including cell proliferation and migration. This reagent can be applied in the preparation of liposomes for drug delivery studies and membrane biophysics research.
a15:0-i15:0 PG sodium is a branched lipid that serves as a significant component in various biochemical assays. Its unique structural properties facilitate research into lipid biology and metabolism. This reagent is particularly useful in studies focusing on membrane dynamics and lipid interactions in cellular systems.
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16:0-17:0 Cyclo PE is a cyclopropyl lipid that serves as a phospholipid analog. It plays a significant role in studying lipid bilayer dynamics and membrane-protein interactions. This compound is particularly useful in researching lipid metabolism and cellular signaling pathways. Its unique structure allows for insights into the influence of lipid composition on membrane properties.
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18:0 Azidoethyl PC is a clickable phospholipid that serves as a valuable tool in lipid research. This compound facilitates the study of lipid behavior and interactions by enabling efficient conjugation with various biomolecules through azide-alkyne cycloaddition reactions. It is particularly useful in applications such as cell membrane labeling, lipid signaling studies, and the development of lipid-based drug delivery systems.
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Synonyms: 1,2-Dipentadecanoyl-sn-glycero-3-phosphocholine
15:0 PC (1,2-Dipentadecanoyl-sn-glycero-3-phosphocholine) is a phosphatidylcholine primarily utilized in the preparation of giant unilamellar vesicles (GUVs). This compound facilitates studies on membrane dynamics, lipid bilayer formation, and drug delivery systems. Its unique fatty acid chain length enhances the stability and properties of lipid formulations in various biological research applications.
18:1(n7)-16:0 PC-IsoPure is an isomerically pure mixed-acyl glycerophospholipid targeting lipid membranes. This compound plays a crucial role in cellular membrane structure and dynamics, making it valuable for studies related to lipid biochemistry, membrane biology, and drug delivery systems. Its high purity enhances experimental reproducibility and reliability in research applications.
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16:0 DGS-NTA(Ni) is a nickel-chelating lipid used to facilitate the purification and immobilization of histidine-tagged proteins. This reagent is particularly valuable in studies involving protein interactions and assays, enabling researchers to examine protein functions and characteristics in a controlled environment. It serves as a critical tool for various applications in biochemistry and molecular biology, particularly in affinity chromatography and protein engineering.
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