Sphingolipids

Sphingolipids are membrane lipids built on a sphingoid base, with ceramide as their central intermediate. In cells, serine and palmitoyl-coenzyme A condense into sphingoid bases, which are then N-acylated to ceramides and extended into sphingomyelin and glycosphingolipids. Ceramides of defined chain length are represented by C6 Ceramide, C8-Ceramide and C24:1-Ceramide, which differ in how they partition into membranes. Glycosphingolipids include Cerebroside B, N-Acetylpsychosine and Ganglioside GT1b (bovine) ammonium, a sialylated ganglioside of neuronal membranes. Compounds directed at the biosynthetic enzymes are listed as well, among them the sphingomyelin synthase inhibitor malabaricone C and the sphingosine kinase inhibitor SKI-I.

Items 201-203 of 203

  • C17 Lactosylceramide (d18:1/17:0)
    Cat. No.
    B21183

    C17 Lactosylceramide (d18:1/17:0)

    C17 Lactosylceramide (d18:1/17:0) is a glycosphingolipid that serves as a key component in the formulation of lipid nanoparticles (LNPs) for targeted drug delivery applications. This compound facilitates the encapsulation and stabilization of therapeutic agents, enhancing bioavailability and efficacy. Research involving C17 Lactosylceramide focuses on its role in cellular signaling and membrane dynamics, making it a valuable tool in lipid chemistry and drug development studies.

    1 mg
    $880.00
    All 1 sizes
  • Lactosyl-b-1,1'-N-octanoyl-L-threo-sphingosine
    Cat. No.
    B21199

    Lactosyl-b-1,1'-N-octanoyl-L-threo-sphingosine

    Synonyms: C8 L-threo-Lactosyl(ß) ceramide (d18:1/8:0)

    Lactosyl-b-1,1'-N-octanoyl-L-threo-sphingosine is a glycosphingolipid that plays a vital role in cellular signaling and membrane dynamics. It is known to participate in cell-cell interactions and is involved in various biological processes, including neuronal development and immune responses. This compound is valuable for research applications focusing on lipid biochemistry, cell biology, and neurobiology.

    Out of stock

    All 3 sizes
  • Ganglioside GD1b (porcine brain) diammonium
    Cat. No.
    B21223

    Ganglioside GD1b (porcine brain) diammonium

    Ganglioside GD1b (porcine brain) diammonium is a glycosphingolipid that plays a crucial role in cell signaling and membrane dynamics. It is primarily involved in neuronal development and function, serving as a key component of lipid rafts which facilitate protein interactions. This reagent is valuable for research applications related to neurobiology, cellular communication, and lipid biochemistry, particularly in the study of ganglioside-mediated processes in neurodegenerative diseases.

    Out of stock

    All 3 sizes

Items 201-203 of 203

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