Antibiotic

Cat. No.

A10653

CAS No.

1476-53-5

Novobiocin sodium

Synonyms: Albamycin sodium; Cathomycin sodium

Novobiocin sodium is a potent antibiotic that primarily targets DNA gyrase, exhibiting significant inhibitory action in various bacterial strains. Additionally, it acts as an antagonist of heat shock protein 90 (Hsp90), expanding its potential applicability in therapeutic research. Novobiocin sodium is particularly valuable for studies on beta-lactam-resistant pneumococcal infections and demonstrates anti-orthopoxvirus activity, highlighting its relevance in infectious disease research.

Cat. No.

A46503

CAS No.

183202-73-5

Kendomycin

Synonyms: (-)-TAN2162

Kendomycin ((−)-TAN 2162) is a polyketide antibiotic primarily targeting bacterial growth inhibition. It exhibits significant antibacterial activity, particularly against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 5 μg/mL. In addition to its antibacterial properties, Kendomycin acts as a potent antagonist of the endothelin receptor and a calcitonin receptor agonist, highlighting its potential applications in anti-osteoporotic research.

Cat. No.

A46506

CAS No.

155773-72-1

PAMAM Dendrimer G0.0 amine (20% in methanol)

PAMAM Dendrimer G0.0 amine is an antibiotic targeting pore-forming toxins, specifically acting as an antagonist to anthrax toxin protective antigen 63 (PA63, IC50 = 231 nM) and C. botulinum C2 toxin subunit (C2IIa, IC50 = 940 nM). At concentrations of 10 and 20 µM, it demonstrates protective effects against C2 toxin-induced cytotoxicity in HeLa cells. Additionally, this compound acts as a nickel chelator and has been employed in the selective capture and storage of carbon dioxide in gas-feed systems when used in conjunction with polysulfone membrane-bound chitosan. PAMAM Dendrimer G0.0 amine serves as a valuable reagent in research focused on infectious diseases, cancer biology, and drug delivery systems.

Cat. No.

A47317

CAS No.

15319-50-3

Ferrimycin A1

Ferrimycin A1 is an iron-containing peptide antibiotic that functions as a competitive antagonist and microbial growth factor. This compound exhibits potent antibacterial activity, making it valuable for research focused on microbial inhibition and the development of new antibiotic therapies. Its unique properties facilitate studies in microbial growth regulation and antibiotic resistance mechanisms.