Biochemical Assay Reagents

Cat. No.

A47943

CAS No.

7601-54-9

Trisodium phosphate

Trisodium phosphate is a food additive that acts as a buffering agent and stabilizer. It influences the growth parameters of Listeria monocytogenes, specifically affecting the lag phase and maximum growth rate. Additionally, Trisodium phosphate enhances the sensitivity of Gram-negative bacteria to antimicrobial agents such as Lysozyme and Nisin, making it valuable for research in food safety and microbiology.

Cat. No.

A65631

CAS No.

2586047-09-6

CDN-A

CDN-A is a cyclic di-nucleotide that serves as a potent stimulator of both innate and adaptive immune responses. It facilitates the synthesis of antibody-drug conjugates (ADCs) and plays a crucial role in immune regulation by activating interferon gene expression. In humans, cyclic di-nucleotides are produced endogenously in response to foreign DNA or by bacterial pathogens, making them vital for stimulating the innate immune system. Research applications include immunotherapy and the study of immune response mechanisms.

Cat. No.

A86471

CAS No.

14379-00-1

Croconic acid disodium

Synonyms: Nacr

Croconic acid disodium is a potent activator of lysine crotonylation (Kcr), promoting cell growth and proliferation through the upregulation of genes associated with Kcr modification. This compound is particularly relevant for enhancing the efficiency of somatic cell nuclear transfer (SCNT) and optimizing conditions in cell culture studies, making it a valuable reagent for researchers focused on cellular dynamics and development.

Cat. No.

A88027

CAS No.

68915-31-1

Sodium polyphosphate, crystal,+200 mesh, 96%

Sodium polyphosphate is a water-soluble inorganic stabilizer that functions as a surfactant and metal ion chelator. With a purity of 96% and a particle size of +200 mesh, this compound demonstrates key biological activity in biochemical assays. It is commonly utilized in various applications, including food, cosmetics, and industrial products, to enhance texture and stability while mitigating metal ion-induced degradation, thereby prolonging shelf life.

Cat. No.

A88993

CAS No.

868843-84-9

BMVC4

BMVC4 is a G-quadruplex (G4) stabilizer specifically targeting the human telomeric sequence d[AG3(T2AG3)3]. This compound exhibits enhanced suitability as a core molecule for G4 stabilizers and demonstrates significant potential for anticancer research applications. Using circular dichroism (CD) spectroscopy, BMVC4 shows improved stability compared to other derivatives in the presence of trivalent cations. Additionally, a rapid screening method utilizing Cu2+-induced G4 unfolding can be employed to identify superior G4 stabilizers, emphasizing BMVC4's role as a promising candidate for further study in therapeutic settings.

Cat. No.

A89020

CAS No.

30403-47-5

1,2-Dihexanoyl-sn-glycerol

1,2-Dihexanoyl-sn-glycerol is a potent activator of protein kinase C (PKC), functioning through the generation of diacylglycerol (DAG) as a second messenger. This compound is utilized as a biochemical assay reagent to study PKC signaling pathways and their effects on various cellular processes. While its biological activity is not fully characterized, it is anticipated to exhibit similar properties to 1,2-dioctanoyl-sn-glycerol, supporting its application in research involving lipid signaling and cell regulation.

Cat. No.

A89274

CAS No.

22432-79-7

Stearyl arachidate

Synonyms: Arachidic acid stearyl ester

Stearyl arachidate is a biochemical assay reagent that serves as a surfactant and stabilizer in various biological applications. It exhibits properties conducive to enhancing solubility and bioavailability of hydrophobic compounds, making it valuable for studies in drug formulation and delivery. This compound is particularly useful in research focused on lipid interactions and membrane biophysics.

Cat. No.

A91358

CAS No.

128446-32-2

β-Cyclodextrin, 2-hydroxyethyl ethers

β-Cyclodextrin, 2-hydroxyethyl ethers functions as a biochemical reagent that primarily acts as a solubilizing agent and stabilizer for various compounds. Its unique structure enhances the solubility of hydrophobic molecules, making it valuable in pharmaceutical and biochemical research applications. It is often used in drug delivery systems, formulation of nanoparticles, and studies involving inclusion complexes to improve the bioavailability of therapeutic agents.

Cat. No.

A93170

CAS No.

1212331-85-5

8(R)-Hydroxyoctadecanoic acid

8(R)-Hydroxyoctadecanoic acid is an ester product known for its role in lipid metabolism. This compound exhibits biological activity as an activator of peroxisome proliferator-activated receptors (PPARs), which are involved in the regulation of fatty acid storage and glucose metabolism. It can be utilized in research applications focused on metabolic disorders, inflammation, and cardiovascular diseases, providing insights into the physiological roles of fatty acids in cellular processes.

Cat. No.

A93290

CAS No.

911102-04-0

BocNH-PEG2-CH2COONHS

BocNH-PEG2-CH2COONHS is a PEG-derived biochemical assay reagent that features a terminal carboxylic acid and a Boc-protected amino group. This hydrophilic PEG spacer enhances the solubility of compounds in aqueous solutions, facilitating diverse biochemical applications. The terminal carboxylic acid readily reacts with primary amine groups, particularly in conjunction with activators like EDC and HATU, to yield stable amide bonds. Deprotection of the Boc group under mild acidic conditions generates a free amine for subsequent reactions.

Cat. No.

A93446

CAS No.

179763-60-1

3-((2-(4-Azidobenzamido)ethyl)disulfanyl)propanoic acid

3-((2-(4-Azidobenzamido)ethyl)disulfanyl)propanoic acid is a versatile biochemical assay reagent featuring an aryl azide, a cleavable disulfide bond, and a carboxylic acid. The aryl azide can be activated with UV light (250 to 350 nm) facilitating biomolecule conjugation. Additionally, the carboxylic acid allows for amide bond formation with amines in the presence of an activator, while the disulfide bond can be cleaved using reducing agents, making this compound useful for various chemical biology applications and protein labeling studies.

Cat. No.

A93858

CAS No.

191163-45-8

4-Azide-TFP-amide-SS-propionic acid

4-Azide-TFP-amide-SS-propionic acid is a biochemical assay reagent featuring an aryl azide, a cleavable disulfide bond, and a carboxylic acid. The aryl azide undergoes photo-activation with UV light (250 to 350 nm), facilitating conjugation with various biomolecules. The carboxylic acid is reactive towards amines in the presence of an activator, allowing for the formation of stable amide bonds. The associated disulfide bond can be selectively cleaved using reducing agents, making this compound valuable for applications in protein labeling and conjugation studies.

Cat. No.

A94952

CAS No.

2566404-74-6

4-Azide-TFP-amide-PEG4-acid

4-Azide-TFP-amide-PEG4-acid is a biochemical assay reagent designed for efficient conjugation reactions. Featuring an aryl azide that can be photo-activated under UV light (250 to 350 nm), it facilitates the covalent attachment to various biomolecules. The inclusion of a PEG spacer enhances aqueous solubility and minimizes steric hindrance during ligation, while the carboxylic acid moiety allows for amine reactions in the presence of an activator to generate stable amide bonds. This reagent is suitable for applications in bioconjugation chemistry and the development of novel biosensors.