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Acyl-coenzyme A (acyl-CoA) compounds and enzyme cofactors supply activated substrates and redox carriers for assays. Acyl-CoA thioesters carry acyl groups through fatty acid metabolism and serve as substrates for acyltransferases, dehydrogenases and carboxylases. Crotonyl-CoA is a short-chain unsaturated thioester and the acyl donor for histone lysine crotonylation. Reduced nicotinamide adenine dinucleotide (NADH) and its phosphorylated form NADPH donate electrons to dehydrogenases and reductases. NADPH is offered in several salt forms, including NADPH tetrasodium salt. Sapropterin dihydrochloride is a synthetic form of tetrahydrobiopterin, the cofactor of aromatic amino acid hydroxylases and nitric oxide synthases. Coenzyme FO, a deazaflavin, is the precursor of coenzyme F420 and a light-harvesting chromophore in some DNA photolyases.
Synonyms: Sulfoacetyl-coenzyme A
Sulfoacetyl-CoA is a coenzyme A derivative that serves as an essential biochemical precursor in various metabolic pathways. It plays a crucial role in the synthesis and regulation of sulfur-containing metabolites. This compound is utilized in research applications involving metabolic studies, enzyme kinetics, and the exploration of cellular pathways that involve sulfur metabolism.
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Synonyms: Gentisyl-coenzyme A
2,5-Dihydroxybenzoyl-CoA is a coenzyme A derivative that serves as an acyl-CoA molecule. This compound is important for studying metabolic pathways involving acylation and can be used in research into the biochemical roles of CoA in various pathways. Its unique structure allows for exploration of its impact on enzymatic reactions and metabolic regulation.
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Synonyms: 4-Methylpentanoyl-coenzyme A
4-Methylpentanoyl-CoA is a derivative of coenzyme A that features a methyl-branched fatty acyl structure. This compound plays a crucial role in metabolic pathways, particularly in the biosynthesis of various lipids and fatty acids. It is primarily utilized in research applications focused on fatty acid metabolism and energy production within cellular systems.
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Synonyms: (Methylenecyclopropyl)formyl coenzyme A; MCPF-CoA
(Methylenecyclopropyl)formyl-CoA is a coenzyme A derivative that acts as an essential intermediate in various biochemical pathways. This compound is primarily involved in fatty acid metabolism and has been utilized in research applications focusing on enzyme activity and metabolic engineering. Its unique structure allows for investigation into the modulation of metabolic pathways related to lipid biosynthesis.
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Synonyms: trans-2-Octenedioyl-coenzyme A
trans-2-Octenedioyl-CoA is a coenzyme A derivative that plays a crucial role in lipid metabolism. It is involved in the activation and transportation of fatty acids for degradation through beta-oxidation. This compound can be utilized in research applications related to metabolic pathways, fatty acid synthesis, and the regulation of lipid metabolism in various biological systems.
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Synonyms: 12-Methyltridecanoyl-coenzyme A; Isotetradecanoyl-CoA; Isotetradecanoyl-coenzyme A
12-Methyltridecanoyl-CoA is a coenzyme A derivative that plays a crucial role in fatty acid metabolism. It acts as an essential acyl donor for various biosynthetic processes and is involved in the regulation of metabolic pathways. This compound is utilized in research on lipid metabolism, fatty acid synthesis, and enzymatic activity related to coenzyme A-dependent reactions.
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Synonyms: (2E,5Z)-Octadienoyl-coenzyme A
(2E,5Z)-Octadienoyl-CoA is a coenzyme A derivative featuring an unsaturated fatty acyl chain. It serves as an important intermediate in fatty acid metabolism and is involved in various biochemical pathways. This reagent is valuable for research applications focused on lipid biosynthesis and metabolic regulation, allowing for the exploration of fatty acid activation and its implications in cellular processes.
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Synonyms: S-Ethylcoenzyme A
S-Ethyl-CoA is a derivative of coenzyme A that serves as an important substrate in various biochemical pathways. It plays a crucial role in the metabolism of fatty acids and participates in the synthesis of acetyl-CoA. This compound is utilized in research applications focused on metabolic studies, enzymatic reactions, and the investigation of coenzyme A-related processes.
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Synonyms: Cyclohexa-1,4-diene-1-carbonyl-coenzyme A
Cyclohexa-1,4-diene-1-carbonyl-CoA is a coenzyme A derivative that plays a key role in various biochemical processes. It serves as a crucial substrate in acylation reactions and is involved in metabolic pathways within cells. Researchers utilize this compound to study its effects on cellular metabolism and to understand the mechanistic roles of coenzyme A derivatives in biochemical pathways.
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Synonyms: 5-Oxooctanoyl-coenzyme A
5-Oxooctanoyl-CoA is a coenzyme A derivative that plays a critical role in fatty acid metabolism. It is involved in the activation of fatty acids for subsequent beta-oxidation, contributing to energy production and lipid biosynthesis. This compound is valuable for research applications focused on metabolic pathways, lipid-related disorders, and therapeutic targets in energy metabolism.
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Synonyms: 11,12-Didehydroacyl-coenzyme A
11,12-Didehydroacyl-CoA is a derivative of coenzyme A that plays a critical role in fatty acid metabolism. It functions as an acyl donor in various biochemical pathways, influencing lipid biosynthesis and degradation. This compound is valuable for research applications in metabolic studies and the investigation of lipid-related disorders.
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Synonyms: Succinamide-coenzyme A
Succinamide-CoA is a coenzyme A derivative that plays a crucial role in cellular metabolism. This compound is involved in various biochemical pathways, including fatty acid synthesis and energy production. Its unique structure enables it to participate in acyl group transfer reactions, making it valuable for studying metabolic processes and enzyme activities in research applications.
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Synonyms: 12-Hydroxyoctadecanoyl-coenzyme A
12-Hydroxyoctadecanoyl-CoA is a hydroxy fatty acyl-CoA derivative that plays a crucial role in various metabolic pathways. It is involved in the synthesis of complex lipids and may influence lipid metabolism and signaling processes. This compound is widely used in biochemical research to study fatty acid metabolism and cellular functions related to lipid intermediates.
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Synonyms: 4-Coumaroyl-CoA; p-coumaroylcoenzyme A
p-Coumaroyl-CoA is a coenzyme A derivative that plays a pivotal role in the biosynthesis of lignin and flavonoids. This compound acts as a critical intermediate, facilitating the enzymatic reactions involved in the formation of these important plant metabolites. Its ability to influence phenolic compound synthesis makes p-Coumaroyl-CoA valuable for research applications in biochemistry and plant biology.
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Synonyms: S-(6-Hydrogen-2-hexenedioate)-Coenzyme A； trans-2,3-Didehydroadipoyl-CoA; trans-2,3-Didehydroadipoyl-coenzyme A
S-(6-Hydrogen-2-hexenedioate)-CoA is a coenzyme A derivative that plays a crucial role in metabolic pathways. This compound serves as an important cofactor involved in the activation of fatty acids and the synthesis of various biochemicals. Its utilization in research facilitates the study of lipid metabolism and the biochemical processes related to energy production and storage.
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Synonyms: 3-Hydroxyhexanoyl-coenzyme A; [R,S]-Lactyl-CoA
3-Hydroxyhexanoyl-CoA is a coenzyme A derivative that plays a crucial role in fatty acid metabolism and energy production. It is instrumental in various biochemical pathways, including beta-oxidation and the synthesis of acyl-CoA thioesters. Researchers utilize this reagent in studies focused on metabolic disorders and enzymatic activities associated with lipid metabolism. Its application extends to understanding the regulation of energy balance and substrate utilization in cellular processes.
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Synonyms: (9Z,12Z)-Tetradecadienoyl-coenzyme A
(9Z,12Z)-Tetradecadienoyl-CoA is a coenzyme A derivative featuring unsaturated fatty acyl moieties. This compound plays a crucial role in fatty acid metabolism and energy production, functioning as a substrate in various enzymatic reactions involved in lipid biosynthesis. Its applications include studying metabolic pathways related to lipid metabolism and investigating the roles of unsaturated fatty acid derivatives in cellular processes.
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Synonyms: (S)-3-Hydroxyl-5-methylhexanoyl-coenzyme A
(S)-3-Hydroxyl-5-methylhexanoyl-CoA is a coenzyme A derivative featuring a hydroxyl group at the 3-position and a branched-chain structure. This compound plays a critical role in metabolic pathways, particularly in the biosynthesis of fatty acids and other important metabolites. It is applicable in biochemical studies focused on energy metabolism and lipid biosynthesis, facilitating the exploration of various cellular processes.
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Synonyms: Isopentadecanoyl-coenzyme A
Isopentadecanoyl-CoA is a coenzyme A derivative that plays a crucial role in fatty acid metabolism. It is involved in the activation of fatty acids for β-oxidation and other metabolic processes. This compound is widely utilized in research applications focusing on lipid metabolism, enzymatic assays, and the study of acyl-CoA synthetases. Isopentadecanoyl-CoA serves as an important tool for investigating the biochemical pathways related to energy production and lipid homeostasis.
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Synonyms: 2,4-Decadienoyl-coenzyme A
2-trans-4-cis-Decadienoyl-CoA is a derivative of coenzyme A featuring an unsaturated fatty acyl chain. It plays a crucial role in fatty acid metabolism, particularly in the elongation and oxidation processes of fatty acids. This compound is relevant for research applications in metabolic biology, lipid metabolism, and the study of enzymatic reactions involving unsaturated fatty acids.
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Synonyms: L-Valine-coenzyme A
L-Valine-CoA is a coenzyme A derivative primarily involved in cellular metabolism. It plays a key role in the biosynthesis of branched-chain amino acids and is important for energy production and metabolic regulation. L-Valine-CoA is suitable for research applications focused on metabolic pathways and enzymatic reactions involving CoA-dependent processes.
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Synonyms: cis-Tetradec-11-enoyl-coenzyme A
11Z-Tetradecenoyl-CoA is a coenzyme A derivative involved in lipid metabolism. It serves as an important acyl-CoA thioester that participates in fatty acid synthesis and degradation. This compound is utilized in research focused on metabolic pathways, enzyme activity assays, and the study of lipid-related diseases.
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Synonyms: Coenzyme A,S-4,7,10,13,16-eicosapentaenoate; (all-E)-
Epa-CoA is a coenzyme A derivative specifically composed of S-4,7,10,13,16-eicosapentaenoate. This compound plays a crucial role in cellular metabolism and lipid biochemistry, influencing fatty acid synthesis and degradation. It is valuable in research applications focused on metabolic pathways and the biology of eicosapentaenoic acid (EPA), making it an essential tool for studies on inflammation and cardiovascular health.
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Synonyms: 2-Methylacetoacetyl-coenzyme A; Alphamethylacetoacetyl-CoA; Alphamethylacetoacetyl coenzyme A
2-Methylacetoacetyl-CoA is a coenzyme A derivative that functions as a 3-oxoacyl-CoA molecule. It is involved in key metabolic pathways, including the biosynthesis of fatty acids and the degradation of certain amino acids. This compound is valuable for research applications focused on metabolism, enzymatic activity, and the regulation of cellular processes related to acyl-CoA derivatives.
Synonyms: 3-(Epoxymethylene)dodecanoyl coenzyme A
3-(Epoxymethylene)dodecanoyl-CoA is a Coenzyme A derivative primarily involved in fatty acid metabolism. This compound serves as a substrate for enzymes that catalyze the synthesis and degradation of fatty acids. Its unique epoxide structure may provide insights into enzyme mechanisms and metabolic pathways, making it valuable for research in lipid metabolism and related biochemical studies.
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