Biochemical Assay Reagents

Cat. No.

A21224

CAS No.

85-32-5

5'-Guanylic acid

Synonyms: 5'-GMP; 5'-guanosine monophosphate

5'-Guanylic acid is a purine nucleotide that serves as a crucial regulator in energy metabolism, signal transduction, and gene expression. It influences the expression of genes associated with fatty acid metabolism and acts as a weak agonist for ionotropic glutamate receptors (iGluR), thereby modulating glutamatergic activity and exhibiting neuroprotective properties. However, at elevated concentrations, 5'-Guanylic acid can induce neuronal cell death. This reagent is valuable for research in metabolic regulation and neurobiology.

Cat. No.

A35842

CAS No.

1217471-69-6

(2S)-OMPT triethylamine, in ethanol:chloroform (1:1), 98%

(2S)-OMPT triethylamine, in ethanol:chloroform (1:1), 98% is a selective agonist for the LPA3 G-protein-coupled receptor. This compound triggers downstream signaling events by activating calcium ion influx and promoting IL-6 release in cancer cells. Additionally, it has been shown to activate MAPK and Akt signaling pathways, making it valuable for research applications focused on ovarian cancer.

Cat. No.

A57970

CAS No.

81319-59-7

7-Methyladenosine perchlorate

7-Methyladenosine perchlorate is a synthetic analog of adenosine that acts as an agonist at adenosine receptors. This compound effectively modulates cellular signaling pathways, making it a valuable reagent for investigating adenosine-related biological processes. Additionally, 7-Methyladenosine perchlorate holds potential as a tool in compound development, particularly as an inhibitor for biochemical assays.

Cat. No.

A59173

CAS No.

220556-69-4

ACEA

Synonyms: Arachidonyl-2-chloroethylamide

ACEA (arachidonyl-2'-chloroacetamide) is a synthetic compound that acts as an agonist of the cannabinoid receptor CB1. It modulates the endocannabinoid system, influencing physiological processes including appetite regulation, pain perception, mood, and memory. This biochemical assay reagent is essential for research exploring the pharmacological effects and therapeutic potential of cannabinoid signaling.

Cat. No.

A59601

CAS No.

149297-81-4

Dicytidine 5′-triphosphate

Synonyms: Cp3C

Dicytidine 5′-triphosphate (Cp3C) is a cytosine-containing dinucleoside polyphosphate that acts as a modulator of intracellular signaling pathways. This compound inhibits the intracellular accumulation of trans-resveratrol and trans-piceid, impacting cellular responses to these natural compounds. Additionally, Dicytidine 5′-triphosphate induces the expression of CCR2 and upregulates the expression of PAL1 and 4CL1, highlighting its potential role in studies related to inflammation and phenylpropanoid metabolism.

Cat. No.

A67077

CAS No.

5550-12-9

5'-Guanylic acid disodium salt

Synonyms: 5'-GMP disodium salt; 5'-guanosine monophosphate disodium salt

5'-Guanylic acid disodium salt is a purine nucleotide that primarily functions as a signaling molecule in various physiological processes, including energy metabolism and gene expression regulation. It plays a crucial role in modulating genes associated with fatty acid metabolism. Additionally, this compound acts as a weak agonist for ionotropic glutamate receptors (iGluR), thereby reducing glutamatergic activity and exerting neuroprotective effects. However, at elevated concentrations, 5'-Guanylic acid disodium salt can induce neuronal cell death, making it valuable for studies on neuroprotection and excitotoxicity.

Cat. No.

A70228

CAS No.

25351-24-0

Gentisuric acid

Gentisuric acid, a metabolite of Aspirin, serves as a substrate for α-amidating monooxygenase (PAM). This compound exhibits protective properties against DNA damage induced by Mitomycin C, making it valuable for research in cellular stress responses and the study of DNA repair mechanisms. Gentisuric acid is essential for understanding the biochemical pathways influenced by Aspirin and its metabolites.

Cat. No.

A71356

CAS No.

14292-27-4

3-Hydroxyoctanoic acid

3-Hydroxyoctanoic acid acts as an agonist for the orphan receptor GPR109B, promoting an increase in intracellular calcium levels in human neutrophils expressing this receptor. This hydroxylated fatty acid, which occurs in the lipopolysaccharides of Pseudomonas aeruginosa and in poly(3-hydroxyalkanoate) produced by Pseudomonas oleophores, plays a role in metabolic studies. Research indicates that 3-hydroxyoctanoic acid interferes with lipolysis in human adipocytes and demonstrates significant changes in plasma levels under various dietary conditions, making it a valuable reagent for biochemical assays focused on metabolic regulation and related disorders.

Cat. No.

A86502

CAS No.

11138-66-2

Xanthan gum

Xanthan gum serves as a hydrogel modulator by enhancing the viscosity and stability of hydrogels through hydrogen bonding interactions with gelatin. This compound not only promotes cell growth but also facilitates a microenvironment that supports cell differentiation. Additionally, xanthan gum has been shown to induce pro-inflammatory responses by elevating levels of inflammatory cytokines such as TNF-α, IL-6, and IL-10. Its properties make xanthan gum a valuable reagent for research in inflammation and immunology.

Cat. No.

A87300

CAS No.

2295-31-0

2,4-Thiazolidinedione

2,4-Thiazolidinedione is a biochemical reagent primarily known for its role as a PPAR gamma agonist, targeting peroxisome proliferator-activated receptors. This compound exhibits significant biological activity in modulating insulin sensitivity and glucose metabolism, making it useful in research focused on diabetes, obesity, and metabolic disorders. Its applications extend to studies investigating cellular processes and the effects of thiazolidinediones in various biological systems.

Cat. No.

A89284

CAS No.

112897-97-9

trans-3,4-Difluorocinnamic acid

Synonyms: (E)-3-(3,4-Difluorophenyl)acrylic acid

trans-3,4-Difluorocinnamic acid is a biochemical reagent that functions as a modulator of signaling pathways by inhibiting specific enzymes involved in tumor growth. Its key biological activities include anti-inflammatory and anticancer effects, making it a valuable tool in cancer research and drug development. This compound can be utilized in various experimental settings to investigate the molecular mechanisms underlying disease processes and to evaluate potential therapeutic strategies.

Cat. No.

A90267

CAS No.

75803-39-3

Ethynyl estradiol 17-β-D-glucuronide

Ethynyl estradiol 17-β-D-glucuronide is a glycosylated form of the estrogen receptor modulator, specifically targeting glycobiology applications. This compound plays a critical role in the study of glycan structures and their biological implications, facilitating research into carbohydrate chemistry, enzyme interactions, and protein-glycan recognition. Its utility extends to investigations in basic research, biomedicine, and biotechnology, aiding in the understanding of glycan-related processes in various biological systems.

Cat. No.

A90590

CAS No.

120225-64-1

CGS 21680 sodium

CGS 21680 sodium is an adenosine A2A receptor agonist that selectively activates the A2A receptor, influencing various signaling pathways. This compound exhibits biological activities such as modulation of neurotransmission and anti-inflammatory effects, making it useful in research involving neurological and cardiovascular studies. It is commonly employed in biochemical assays to explore the roles of adenosine receptors in cellular processes and their potential therapeutic applications.

Cat. No.

A90699

CAS No.

1667762-62-0

Recanaclotide

Synonyms: IW-9179

Recanaclotide is a biochemical reagent that acts as a selective guanylate cyclase-C receptor agonist. It has been shown to modulate gastrointestinal motility and fluid secretion, making it relevant for research on gastroparesis, functional dyspepsia, and various gastrointestinal disorders. This compound provides valuable insights into gut physiology and potential therapeutic interventions.

Cat. No.

A91699

CAS No.

113680-55-0

3,17β-O-Bis(methoxymethyl)estradiol

3,17β-O-Bis(methoxymethyl)estradiol is a biochemical assay reagent that functions as a selective estrogen receptor modulator. This compound exhibits significant biological activity by modulating estrogen receptor pathways, making it useful in various research applications, including hormone signaling studies and the investigation of estrogen-related diseases. Its unique structure and properties facilitate the study of estrogen receptor interactions and can aid in the development of therapeutic interventions.

Cat. No.

A91746

CAS No.

67232-80-8

Dimyristoylphosphatidylglycerol sodium

Dimyristoylphosphatidylglycerol sodium is a biochemical assay reagent that primarily functions as a phospholipid modulator. It plays a critical role in membrane-related studies due to its ability to influence membrane fluidity and stability. This compound is often utilized in research applications such as vesicle formation, liposome preparation, and membrane protein interactions, making it an essential tool for researchers investigating lipid biochemistry and cellular processes.

Cat. No.

A92050

CAS No.

6173-35-9

17β-Acetoxy-2α-bromo-5α-androstan-3-one

17β-Acetoxy-2α-bromo-5α-androstan-3-one is a biochemical assay reagent that functions as a steroid derivative. This compound exhibits significant biological activity as a selective androgen receptor modulator, making it useful for research focused on steroid hormone signaling and metabolic processes. It is valuable for studies investigating androgen-related disorders and the mechanistic pathways influenced by androgens in various biological systems.

Cat. No.

A92502

CAS No.

1465-16-3

1-Methylpsilocin

1-Methylpsilocin is a biochemical assay reagent that primarily acts as a selective agonist of serotonin receptors, particularly the 5-HT2A subtype. It exhibits notable hallucinogenic properties and influences various neural pathways associated with mood and perception. This compound is utilized in research applications focused on neuropharmacology, psychopharmacology, and studies investigating the mechanisms of psychedelic compounds.

Cat. No.

A92970

CAS No.

39491-53-7

5'-Ethylcarboxamido-2',3'-isopropylidene adenosine

5'-Ethylcarboxamido-2',3'-isopropylidene adenosine is a selective agonist targeting A2B adenosine receptors. This compound enhances A2B receptor activity, making it valuable for investigating the physiological roles of adenosine signaling in various biological processes. It serves as a pertinent tool in biochemical assays and research applications aimed at understanding adenosine's effects and its potential as a therapeutic target in drug development.

Cat. No.

A93198

CAS No.

61423-61-8

2-Aminoethyl ((R)-2,3-bis(hexadecyloxy)propyl) hydrogen phosphate

2-Aminoethyl ((R)-2,3-bis(hexadecyloxy)propyl) hydrogen phosphate functions as an ester product. This compound is utilized in biochemical research for its role in lipid-based systems and as a potential modulator of cellular membrane dynamics. Its application extends to studies on membrane biophysics and the design of novel drug delivery systems.

Cat. No.

A93454

CAS No.

3158-47-2

6-Hydroxyoctadecanoic acid

6-Hydroxyoctadecanoic acid is a fatty acid derivative characterized by its hydroxyl group at the sixth carbon position. This compound exhibits significant biological activity as a potential modulator of lipid metabolism and plays a role in cell signaling pathways. It is utilized in various research applications including studies on metabolic diseases, lipid biochemistry, and the development of novel therapeutic agents targeting metabolic disorders.

Cat. No.

A93483

CAS No.

911634-03-2

Methyl 14(S),15(S)-epoxy-11(R,S)-hydroxy-5(Z),8(Z),12(E)-eicosatrienoate

Methyl 14(S),15(S)-epoxy-11(R,S)-hydroxy-5(Z),8(Z),12(E)-eicosatrienoate is a bioactive ester compound. It serves as a significant modulator of lipid metabolism and is utilized in research focused on lipid signaling pathways. This compound may be applicable in studies exploring the roles of fatty acid derivatives in cellular processes and their implications in various diseases.

Cat. No.

A93646

CAS No.

779333-58-3

Oleoyl 3-carbacyclic phosphatidic acid

Synonyms: 3-ccPA 18:1

Oleoyl 3-carbacyclic phosphatidic acid is a biochemical reagent that serves as a modulator of lipid signaling pathways. This compound has been shown to enhance the activity of certain phospholipase enzymes, thereby influencing cellular processes such as proliferation and apoptosis. Its unique structure makes it a valuable tool for investigating lipid metabolism and the role of phosphatidic acid in various biological phenomena.

Cat. No.

A93712

CAS No.

82494-50-6

S-Nitroso-CoA

Synonyms: S-Nitroso-coenzyme A; SNO-CoA; SNO-coenzyme A

S-Nitroso-CoA is a nitrosothiol derivative of coenzyme A, where the thiol group has been substituted with a nitrososulfanediyl group. This compound plays a crucial role in nitric oxide signaling pathways and has implications in redox biology. Researchers utilize S-Nitroso-CoA to investigate its effects on cellular processes such as metabolism, signal transduction, and as a potential modulator in various disease models.

Cat. No.

A94132

CAS No.

3891-98-3

Farnesane

Synonyms: 2,6,10-Trimethyldodecane; Hemisqualane

Farnesane (2,6,10-Trimethyldodecane; Hemisqualane) is an isoprenoid derivative targeting biochemical pathways in insects. It serves as a modulator of juvenile hormone activity, making it valuable for studies in insect physiology and development. This compound is suitable for research applications aimed at understanding hormonal regulation and insect growth processes.