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IPA-3
Catalog No. A21182 PAK1 inhibitorIPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC50 of 2.5 μM, and shows no inhibition to group II PAKs (PAKs 4-6). Learn More -
GNE 2861
Catalog No. A21697 PAK inhibitorGNE 2861 is a PAK inhibitor that displays group II selectivity. GNE 2861 inhibits PAK4, PAK5 and PAK6 with IC50s of 7.5, 36, 126 nM, respectively. Learn More -
PF-3758309
Catalog No. A11930 PAK4 inhibitorPF-3758309 is a small-molecule p21-activated kinase inhibitor inhibiting oncogenic signaling and tumor growth. Learn More -
LOR-253
Catalog No. A13838 MTF-1 inhibitorLOR-253 is a small molecule inhibitor of human metal-regulatory transcription factor 1 (MTF-1). Learn More -
FRAX597
Catalog No. A12553 PAK inhibitorFRAX597, a small-molecule pyridopyrimidinone, is a potent and ATP competitive inhibitor of the group I PAKs (PAK1 IC50= 8 nM, PAK2 IC50= 13 nM, PAK3 IC50= 19 nM). Learn More -
FRAX1036
Catalog No. A16557 PAK inhibitorFRAX1036 is a PAK inhibitor with Kis of 23.3 nM, 72.4 nM, and 2.4 μM for PAK1, PAK2 and PAK4, respectively. Learn More -
NVS-PAK1-1
Catalog No. A12708 allosteric PAK1 inhibitorNVS-PAK1-1 is a potent and selective allosteric PAK1 inhibitor with an IC50 of 5 nM. Learn More
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