PAK

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  1. PF-3758309

    Catalog No. A11930
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    PAK4 inhibitor
    PF-3758309 is a small-molecule p21-activated kinase inhibitor inhibiting oncogenic signaling and tumor growth. Learn More
  2. LOR-253

    Catalog No. A13838
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    MTF-1 inhibitor
    LOR-253 is a small molecule inhibitor of human metal-regulatory transcription factor 1 (MTF-1). Learn More
  3. FRAX486

    Catalog No. A13691
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    PAK inhibitor
    FRAX486 is a small-molecule PAK inhibitor. Learn More
  4. KPT-9274

    Catalog No. A15506
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    PAK4 Inhibitor
  5. FRAX597

    Catalog No. A12553
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    PAK inhibitor
    FRAX597, a small-molecule pyridopyrimidinone, is a potent and ATP competitive inhibitor of the group I PAKs (PAK1 IC50= 8 nM, PAK2 IC50= 13 nM, PAK3 IC50= 19 nM). Learn More
  6. FRAX1036

    Catalog No. A16557
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    PAK inhibitor
    FRAX1036 is a PAK inhibitor with Kis of 23.3 nM, 72.4 nM, and 2.4 μM for PAK1, PAK2 and PAK4, respectively. Learn More
  7. NVS-PAK1-1

    Catalog No. A12708
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    allosteric PAK1 inhibitor
    NVS-PAK1-1 is a potent and selective allosteric PAK1 inhibitor with an IC50 of 5 nM. Learn More

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