Nucleoside Antimetabolite/Analog

Cat. No.

A56381

CAS No.

172324-59-3

3a,7a,12a-Trihydroxy-5b-24-oxocholestanoyl-CoA

Synonyms: 3α,7α; 12α-Trihydroxy-24-oxo-5β-cholestan-26-oyl-CoA

3a,7a,12a-Trihydroxy-5b-24-oxocholestanoyl-CoA is a coenzyme A analog that serves as a crucial substrate in the investigation of β-oxidation processes specific to bile acid biosynthesis. This compound enables researchers to explore metabolic pathways and enzyme activities associated with cholesterol derivatives. Its utility in biochemical assays makes it a valuable tool for studies focused on lipid metabolism and biosynthetic regulation.

Cat. No.

A56460

CAS No.

178859-78-4

(S)-2-Acetamido-6-oxopimelic acid

(S)-2-Acetamido-6-oxopimelic acid serves as a substrate for N-succinyl-LL-diaminopimelate aminotransferase (DAP-AT). This compound is crucial for studying the enzymatic pathways involved in bacterial lysine biosynthesis. Its use can facilitate research into antibiotic resistance and the development of new antimicrobial agents targeting DAP-AT-related processes.

Cat. No.

A56470

CAS No.

95140-33-3

N4-Methyl-CTP

N4-Methyl-CTP is a nucleoside analog that serves as a monomeric substrate for nucleic acid synthesis. This compound can be incorporated into RNA and DNA strands, facilitating studies in molecular biology, gene editing, and therapeutic development. Its unique methyl group may also influence nucleotide interactions, making it valuable for exploring nucleic acid structure and function.

Cat. No.

A56502

CAS No.

5536-30-1

5-Amino-2'-deoxyuridine

5-Amino-2'-deoxyuridine is a thymidine analogue that serves as a substrate in various chemical reactions. It is primarily utilized in the synthesis of labeled probes for DNA microarray analysis, facilitating the study of gene expression and genomic variations. This compound is instrumental in nucleic acid research, providing a valuable tool for molecular biology applications.

Cat. No.

A56504

CAS No.

2110479-24-6

3′-O-Azidomethyl-dAMP

3′-O-Azidomethyl-dAMP is a nucleoside analog that serves as a monomeric substrate for nucleic acid synthesis. This compound is instrumental in the preparation of modified oligonucleotides and can be utilized in various biochemical applications such as gene editing, and the development of diagnostic tools. Its unique azido group facilitates subsequent reactions in click chemistry, enhancing functionalization possibilities in molecular biology research.

Cat. No.

A56510

CAS No.

65360-02-3

N-Acetyl-2',3'-acetyl-guanosine

N-Acetyl-2',3'-acetyl-guanosine is a modified guanosine nucleoside that serves as a substrate for various enzymatic processes. This compound is utilized in biochemical research to study nucleoside metabolism and nucleotide synthesis. Its unique acetyl modifications enhance solubility and stability, making it suitable for exploring nucleoside interactions and applications in RNA biochemistry.

Cat. No.

A56511

CAS No.

1220515-98-9

3'-ONH2-dGTP

3'-ONH2-dGTP is a nucleoside analog that serves as a crucial monomeric substrate for nucleic acid synthesis. Its unique chemical structure allows for incorporation into DNA and RNA, facilitating studies in molecular biology, genetic engineering, and pharmacology. This reagent is instrumental for researchers exploring nucleotide modifications and their implications in various biological processes.

Cat. No.

A56530

CAS No.

118353-34-7

CTPαS (Sp isomer)

CTPαS (Sp isomer) is a nucleoside analog that serves as a crucial monomeric substrate for nucleic acid synthesis. This compound is particularly valuable in the study of molecular biology and genetic research, facilitating the development of oligonucleotides and other nucleic acid-based technologies. Researchers can utilize CTPαS (Sp isomer) to explore nucleotide incorporation mechanisms and investigate various biochemical pathways.

Cat. No.

A56541

CAS No.

71376-96-0

GTPαS

GTPαS is a stable analog of guanosine triphosphate (GTP) that acts as a substrate for nucleic acid synthesis. It is predominantly utilized in cellular signaling studies and can inhibit GTPase activities, serving as a valuable tool in examining the functions of GTP-binding proteins. Its applications extend to investigations in molecular biology, particularly in the study of gene expression and regulatory mechanisms.

Cat. No.

A56543

CAS No.

18883-94-8

dTTPαS

dTTPαS is a nucleoside analog that serves as a substrate for DNA polymerases during nucleic acid synthesis. It is utilized in research applications involving DNA replication and transcription studies. Its incorporation into DNA can aid in the design of experiments focusing on nucleotide incorporation fidelity and the exploration of DNA repair mechanisms.

Cat. No.

A56565

CAS No.

208193-48-0

1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite

1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine analog that acts as an effective substrate for DNA polymerases. This compound exhibits incorporation activity into replicated DNA, making it a valuable tool for labeling and tracking DNA synthesis in various biological studies. Its unique structural modifications enable researchers to explore nucleotide dynamics and cellular activities related to DNA replication.

Cat. No.

A56566

CAS No.

84472-90-2

3'-NH2-ddC

3'-NH2-ddC is a nucleoside analog that serves as a vital precursor in nucleic acid synthesis. Its primary mechanism involves acting as a substrate for DNA polymerases, facilitating the incorporation of this modified nucleotide into DNA strands. This compound is essential for research applications in molecular biology, particularly in the development of antiviral therapies and in the study of nucleic acid structures.

Cat. No.

A56579

CAS No.

132471-93-3

3'-O-Phthalimido-2'-dA

3'-O-Phthalimido-2'-dA is a nucleoside analog that serves as a versatile monomeric substrate in nucleic acid synthesis. Its structural modifications facilitate the incorporation of modified nucleotides into oligonucleotides, enhancing their stability and functionality. This reagent is essential for applications in molecular biology, particularly in the design and development of oligonucleotide-based therapeutics and probes.

Cat. No.

A56593

CAS No.

54619-78-2

Cytidine-5'-triphosphate trisodium

Synonyms: Cytidine triphosphate trisodium; 5'-CTP trisodium

Cytidine-5'-triphosphate trisodium is a nucleoside analog that serves as a critical monomer for nucleic acid synthesis. Its primary mechanism involves acting as a substrate for RNA polymerases and kinases, facilitating the incorporation of cytidine into RNA strands. This compound is essential for various applications in molecular biology, including RNA synthesis, enzyme studies, and nucleotide metabolism research.

Cat. No.

A56595

CAS No.

39749-90-1

5-Hme-CTP

5-Hme-CTP is a monomeric nucleoside analog that serves as a substrate for nucleic acid synthesis. This compound is utilized in research applications involving the design and analysis of nucleic acid sequences, enabling the study of various biological processes. Its incorporation into nucleic acids can facilitate investigations into gene expression, replication, and repair mechanisms.

Cat. No.

A56598

CAS No.

1251838-93-3

4'-Fluorouridine triphosphate

Synonyms: 4'-F-UTP

4'-Fluorouridine triphosphate (4'-F-UTP) is a nucleoside analog that serves as a substrate for RNA synthesis. It incorporates into RNA molecules, allowing for the study of RNA behavior and function. This reagent is valuable in research applications such as exploring RNA modification, gene expression, and the mechanism of action of antiviral compounds.

Cat. No.

A56599

CAS No.

51549-37-2

3'-O-TBDMS-2'-dC(Bz)

3'-O-TBDMS-2'-dC(Bz) is a nucleoside analog that serves as a key monomeric substrate for nucleic acid synthesis. This compound is utilized in the construction of oligonucleotides, enabling studies in genetic engineering, molecular biology, and therapeutic development. Its unique structural features facilitate incorporation into DNA and RNA sequences, making it a valuable reagent for researchers in the field of nucleic acid chemistry.

Cat. No.

A56640

CAS No.

163586-84-3

SPS ATP

SPS ATP is a nucleoside analog that serves as a critical monomeric substrate in nucleic acid synthesis. Its incorporation into RNA and DNA strands enables the study of nucleic acid structure and function. This reagent is essential for applications in molecular biology, including the development of RNA therapies and the exploration of genetic mechanisms.

Cat. No.

A56643

CAS No.

847647-85-2

2'-O-MOE-GTP

2'-O-MOE-GTP is a nucleoside analog that serves as a substrate in the synthesis of oligonucleotides. Its unique substitution at the 2' position enhances the stability and binding affinity of RNA molecules. This compound is widely utilized in RNA research, including studies on RNA interference and the development of therapeutics targeting RNA-based diseases.

Cat. No.

A56679

CAS No.

69304-38-7

3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)uridine

Synonyms: 3',5'-TIPS-Uridine

3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)uridine is a nucleoside analog that serves as a valuable monomeric substrate for nucleic acid synthesis. Its unique siloxane linkage enhances the stability and solubility of nucleotides in various biochemical applications. This compound is ideal for researchers engaged in synthetic biology, genetic engineering, and the development of RNA-based therapeutics.

Cat. No.

A56686

CAS No.

154121-10-5

5-Hydroxy-dCTP

5-Hydroxy-dCTP is a nucleoside analog that serves as a substrate for DNA polymerases during nucleic acid synthesis. Its incorporation into DNA can facilitate studies of replication dynamics and mutagenesis. This reagent is invaluable in molecular biology and biochemical research applications involving DNA manipulation and analysis.

Cat. No.

A56690

CAS No.

3056945-44-6

isoGTP lithium

Synonyms: Isoguanosine-5'-triphosphate lithium

isoGTP lithium is a guanosine triphosphate analog that serves as a substrate for various GTP-binding proteins. It is utilized in research to investigate GTPase activity and to study cellular signaling pathways that are mediated by GTP. This compound is valuable for exploring the biological roles of GTP in processes such as protein synthesis and signal transduction.

Cat. No.

A56695

CAS No.

863408-40-6

5'-O-DMTr-2'-O-(2-cyanoethoxymethyl)-rU

5'-O-DMTr-2'-O-(2-cyanoethoxymethyl)-rU is a nucleoside analog that serves as a monomeric substrate for nucleic acid synthesis. This compound is designed to facilitate the incorporation of modified nucleotides into oligonucleotides, enhancing stability and functionality. Its applications include the development of therapeutic oligonucleotides and RNA-based research studies.

Cat. No.

A56697

CAS No.

58976-49-1

Rp-ATPαS

Rp-ATPαS is a nucleoside analog that functions as a substrate for nucleic acid synthesis. This compound is instrumental in various biochemical research applications, particularly in studying RNA and DNA processes. Its unique structural features make it a valuable tool in the investigation of enzymatic reactions and nucleic acid modifications.

Cat. No.

A56700

CAS No.

23339-44-8

3'-P-ATP

3'-Phospho-ATP (3'-P-ATP) is a nucleoside analog that serves as a critical substrate in nucleic acid synthesis. Its primary mechanism involves acting as a phosphorylated nucleotide precursor, facilitating the incorporation of RNA and DNA during polymerization processes. This compound is essential for research applications in molecular biology, including genetic engineering, transcription studies, and nucleic acid assay development.