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Citations
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AZD6642 is an inhibitor of 5-Lipoxygenase Activating Protein (FLAP) for the treatment of inflammatory diseases.
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AM679 is a potent and selective FLAP inhibitor with IC50s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively.
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MK-0591 is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor with an IC50 value of 1.6 nM in a FLAP binding assay.
- MA Sartim, .et al. , Biomolecules, 2020, May; 10(5): 794 PMID: 32443924
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MK591 is selective and specific inhibitor of 5-Lipoxygenase-activating protein (FLAP).
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GSK2190915 is a potent FLAP(5-Lipoxygenase-activating protein) inhibitor with binding IC50 of 2.9 nM.
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AM 103 is a potent and selective FLAP inhibitor, with an IC50 value of 4.2 nM.
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Inhibitor