Fatty Acids & Derivatives

Cat. No.

A48691

CAS No.

1469713-10-7

(±)14(15)-EET Ethanolamide

Synonyms: (±)14(15)-Epoxy eicosatrienoyl ethanolamide

(±)14(15)-EET Ethanolamide is a fatty acid monoepoxide that primarily targets lipid signaling pathways. This compound exhibits anti-inflammatory properties and is significant in the study of Pseudomonas aeruginosa infections and respiratory diseases. Researchers can utilize (±)14(15)-EET Ethanolamide to investigate its potential therapeutic roles and molecular mechanisms within these contexts.

Cat. No.

A49296

CAS No.

3032387-88-2

FASN-IN-6

FASN-IN-6 is a potent inhibitor of fatty acid biosynthesis (FAB). It demonstrates significant antibacterial activity, exhibiting minimum inhibitory concentrations (MIC) of 1 μg/mL against Staphylococcus aureus ATCC 25923 and 4 μg/mL against Enterococcus faecalis ATCC 29212. This compound is valuable for research applications focused on bacterial fatty acid biosynthesis and the development of novel antibacterial strategies.

Cat. No.

A49528

CAS No.

528583-89-3

17(R)-Resolvin D4

Synonyms: 17(R)-RvD4

17(R)-Resolvin D4 is the R-enantiomer of Resolvin D4, a specialized pro-resolving mediator known for its anti-inflammatory properties. This compound plays a crucial role in promoting the resolution of inflammation, particularly during S. aureus infections. Its biological activity makes it valuable in research investigating inflammatory processes and the mechanisms of resolution in various disease models.

Cat. No.

A49878

CAS No.

103904-74-1

Anacardic acid diene

Synonyms: Anacardic acid 15:2

Anacardic acid diene is a polyunsaturated fatty acid that targets various biological processes. It demonstrates significant antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus mutans, with minimum inhibitory concentrations (MICs) of 12.5 and 6.25 μg/mL, respectively. Additionally, Anacardic acid diene exhibits schistosomicidal properties against adult Schistosoma mansoni worms at a concentration of 100 μM and acts as a time-dependent inhibitor of soybean lipoxygenase-1. This compound is valuable for research into antibacterial agents, schistosomiasis treatment, and lipoxygenase inhibition.

Cat. No.

A50363

CAS No.

67042-09-5

10(S)-Hydroxystearic acid

Synonyms: (S)-10-Hydroxyoctadecanoic acid; (S)-10-HSA

10(S)-Hydroxystearic acid, a hydroxy fatty acid and a derivative of oleic acid, primarily functions as a drug derivative. This compound exhibits significant biological activity relevant to infection research, making it a valuable reagent for studying disease mechanisms and potential therapeutic interventions. Its unique properties facilitate investigations into lipid metabolism and inflammation pathways.

Cat. No.

A50554

CAS No.

1518800-36-6

Afabicin diolamine

Synonyms: Debio 1450 diolamine; AFN-1720 diolamine

Afabicin diolamine is the proagent of Debio1452, specifically designed to target Staphylococcus species by inhibiting FabI, a crucial enzyme in fatty acid biosynthesis. This compound demonstrates potent antibacterial activity against Staphylococcus without significant effects on other Gram-positive or Gram-negative organisms. It is invaluable for research applications focused on staphylococcal infections and fatty acid metabolism.

Cat. No.

A52233

CAS No.

14113-05-4

Royal Jelly acid

Synonyms: (E)-Queen Bee Acid; (E)-10-Hydroxy-2-decenoic acid

Royal Jelly Acid, also known as (E)-Queen Bee Acid, is a significant fatty acid derived from royal jelly that demonstrates oral bioavailability. This compound exhibits notable biological activities, including anti-inflammatory, anticancer, antimalarial, antiprotozoal, and neuroregulatory effects. Royal Jelly Acid is applicable in research across multiple fields, such as cancer biology, infectious diseases, immune responses, and neurological disorders.

Cat. No.

A59260

CAS No.

1415264-56-0

Virodhamine TFA

Virodhamine TFA is an endocannabinoid that targets cannabinoid (CB) receptors, acting as an antagonist of the CB1 receptor while functioning as an agonist for the CB2 receptor. This compound induces megakaryocytic differentiation through the activation of MAPK signaling pathways and the production of reactive oxygen species (ROS). Virodhamine TFA is valuable for research related to neurological disorders, including Alzheimer's and Parkinson's diseases, offering insights into the modulation of neurotransmission and cellular differentiation.

Cat. No.

A59344

CAS No.

390824-20-1

UCM707

UCM707 is a potent and selective endocannabinoid uptake inhibitor. By inhibiting the reuptake of anandamide, it enhances its hypokinetic and antinociceptive effects, making it a valuable tool for studying the endocannabinoid system. This compound is useful in research applications related to pain management and the modulation of motor activity.

Cat. No.

A59356

CAS No.

887405-21-2

Nervonoyl ethanolamide

Synonyms: NEA

Nervonoyl ethanolamide (NEA) acts on the endocannabinoid system as a neuromodulator, influencing both presynaptic and postsynaptic signaling pathways. In addition to its role in modulating neural activity, NEA is also useful in the investigation of inflammatory processes. This compound provides valuable insights for research focused on neurobiology and inflammation-related studies.

Cat. No.

A60851

CAS No.

1609382-32-2

Resolvin D5 n-3 DPA

Resolvin D5 n-3 DPA is a specialized proresolving lipid mediator derived from docosapentaenoic acid. It acts as an agonist for GPR101, GPR12, and GPR84, displaying EC50 values of 4.6 pM, 14 pM, and 1.5 pM, respectively. This compound exhibits potent anti-inflammatory and pro-resolution properties, effectively reducing cell adhesion on TNF-α-activated human endothelial monolayers. Furthermore, Resolvin D5 n-3 DPA enhances leukocyte functions, promoting the phagocytic activity of neutrophils and macrophages, making it valuable in research related to intestinal inflammation.

Cat. No.

A64488

CAS No.

26198-80-1

1a,1b-Dihomo prostaglandin E2

Synonyms: 1a,1b-Dihomo PGE2

1a,1b-Dihomo Prostaglandin E2 (PGE2) is an unsaturated fatty acid that serves as a bioactive lipid mediator. This compound demonstrates significant involvement in inflammatory responses and immune modulation, particularly within activated macrophages. It is frequently utilized in research to study the biochemical pathways of prostaglandin metabolism and the functional roles of eicosanoids in cellular signaling and inflammation.

Cat. No.

A65880

CAS No.

162067-50-7

Butyryl-L-carnitine chloride

Butyryl-L-carnitine chloride is an acylcarnitine that plays a crucial role in fatty acid metabolism by facilitating the transport of long-chain fatty acids into the mitochondria for β-oxidation. This compound has demonstrated significant biological activity in metabolic studies and is often used in research applications investigating mitochondrial function, energy metabolism, and related metabolic disorders. Additionally, it serves as a valuable biomarker in clinical studies focused on metabolic health.

Cat. No.

A65942

CAS No.

23048-75-1

10-Hydroxyhexadecanoic acid

10-Hydroxyhexadecanoic acid is a hydroxy fatty acid that targets key lipid transport processes. It effectively promotes cholesterol efflux via the transporters ABCA1 and ABCG1, thereby mitigating excess intracellular cholesterol accumulation. This reagent is valuable for research applications related to anti-atherosclerosis and lipid metabolism.

Cat. No.

A67838

CAS No.

211100-24-2

(17E)-Prostaglandin F3α

Synonyms: 17-trans-PGF3α

(17E)-Prostaglandin F3α is a double bond isomer of Prostaglandin F3α, functioning primarily through the prostaglandin pathway. This compound exhibits significant anti-inflammatory properties, making it valuable for research into inflammation-related conditions and the biological effects of dietary fatty acids. Its potential role as a metabolite of trans dietary fatty acids further supports its relevance in nutritional and metabolic studies.

Cat. No.

A67842

CAS No.

745-64-2

Prostaglandin F3α

Synonyms: PGF3α

Prostaglandin F3α (PGF3α) is a bioactive lipid mediator derived from eicosapentaenoic acid (EPA) known for its anti-cancer and anti-inflammatory properties. It functions as a substrate for the ATP-binding cassette transporter ABCC4, exhibiting a Km of 12.1 μM. PGF3α is particularly relevant for research involving metabolic conditions, including diabetes, offering insights into its underlying mechanisms and potential therapeutic targets.

Cat. No.

A68190

CAS No.

2764-03-6

Linoleoyl glycine

Linoleoyl glycine is a modified polyunsaturated fatty acid that primarily targets human KCNQ1/KCNE1 channels. It has been shown to activate these channels when expressed in Xenopus oocytes, demonstrating significant potential for research in cardiac ion channel physiology. This compound can be utilized to study the modulation of membrane potentials and the effects of fatty acid derivatives on channel activity.

Cat. No.

A69256

CAS No.

78991-74-9

Bay-02752

Synonyms: Bay o 2752

Bay-02752 is a lipid-lowering agent that primarily inhibits acyl-CoA activity in liver microsomes, exhibiting an IC50 of 0.95 μg/mL. This compound effectively reduces intestinal cholesterol absorption in rat models and has been shown to inhibit gallstone formation in hamsters. Bay-02752 serves as a valuable research tool for studying lipid metabolism and potential therapeutic strategies for hyperlipidemia.

Cat. No.

A69419

CAS No.

1120-28-1

Methyl arachidate

Synonyms: Methyl icosanoate

Methyl arachidate, also known as methyl icosanoate, is a lipid component that specifically inhibits leukotriene A4 hydrolase (LTA4H). This compound is derived from various flowering plants and exhibits no antifeedant activity against Leptinotarsa decemlineata, making it a relevant candidate for studies in lipid metabolism and plant-insect interactions. Its unique properties can be useful in research applications focusing on lipid function and bioactivity in plant systems.

Cat. No.

A69607

CAS No.

9013-18-7

Acyl coenzyme A synthetase

Synonyms: ACS

Acyl coenzyme A synthetase (ACS) primarily targets acetyl-CoA synthetase and plays a crucial role in fatty acid metabolism. This enzyme catalyzes the activation of fatty acids by coenzyme A through a two-step thioesterification reaction, resulting in the production of acyl-CoA. Acyl-CoA is essential for various anabolic and catabolic lipid metabolism pathways and is involved in the TCA cycle during aerobic respiration, making it a vital component in energy production and metabolic regulation studies.

Cat. No.

A70173

CAS No.

119433-37-3

14(S)-HDHA

Synonyms: 14(S)-HDoHE

14(S)-HDHA is an oxygenation product derived from Docosahexaenoic acid (DHA), targeting the carbon 14-lipoxygenation pathway. It serves as a significant biomarker for assessing the activation of this pathway, and it is essential for research applications focusing on lipid metabolism and inflammatory processes. 14(S)-HDHA can be utilized in studies examining the impact of DHA on cellular signaling and potential therapeutic roles in various disease states.

Cat. No.

A70349

CAS No.

87042-40-8

(±)14-HDHA

Synonyms: (±)14-HDoHE; 14-hydroxy Docosahexaenoic acid

(±)14-HDHA is an oxygenation product of Docosahexaenoic acid (DHA), specifically functioning as a target for lipoxygenase pathways. It serves as a key marker for the activation of the carbon 14-lipoxygenation pathway related to DHA metabolism. This compound is valuable for research in lipid biochemistry and its role in inflammatory processes, shedding light on potential therapeutic targets in various diseases.

Cat. No.

A70375

CAS No.

799812-85-4

Myristoyl coenzyme A triammonium

Synonyms: 14:0 Coenzyme A triammonium; S-Tetradecanoate-CoA triammonium; S-Tetradecanoate-coenzyme A triammonium

Myristoyl coenzyme A triammonium is an activated form of long-chain fatty acids, specifically classified as a long-chain acyl-CoA. It plays a significant role as a lipid metabolite, involved in various metabolic processes. This compound is essential for studying lipid metabolism, fatty acid synthesis, and related biochemical pathways in cellular and molecular research applications.

Cat. No.

A70465

CAS No.

168111-97-5

(±)17(18)-DiHETE

(±)17(18)-DiHETE is an oxidized lipid and a metabolite of Eicosapentaenoic Acid, an essential omega-3 long-chain polyunsaturated fatty acid. This compound exhibits bioactive properties that may influence inflammatory processes and cellular signaling pathways. It is widely utilized in research applications focused on lipid metabolism, oxidative stress, and the role of oxylipins in various physiological and pathological conditions.

Cat. No.

A70604

CAS No.

141545-44-0

9(S)-HEPE

9(S)-HEPE, a hydroxy fatty acid, is a bioactive metabolite of eicosapentaenoic acid. This compound plays a crucial role in inflammatory response modulation and has been shown to exhibit beneficial effects on vascular health. Its research applications extend to studies involving lipid metabolism, inflammatory processes, and potential therapeutic effects in cardiovascular diseases.