Fatty Acids & Derivatives

Cat. No.

A72104

CAS No.

71030-39-2

5-HETE

Synonyms: (±)-5-HETE

5-HETE, an oxidative derivative of arachidonic acid, functions as a potent aggregating agent, promoting neutrophil aggregation. The compound exists as a mixture of 5(S)-HETE and 5(R)-HETE. Its biological activity is characterized by an IC50 value of 200 nM, making it valuable for research focused on inflammatory responses and immune system modulation. 5-HETE is relevant for studies investigating leukocyte behavior and the role of lipid mediators in various physiological and pathological processes.

Cat. No.

A72165

CAS No.

3639-21-2

2-Ethyl-2-hydroxybutanoic acid

Synonyms: 2-Ethyl-2-hydroxybutyric acid

2-Ethyl-2-hydroxybutanoic acid is a hydroxy fatty acid and a metabolite of di(2-ethylhexyl) phthalate (DEHP). This compound is significant in research related to metabolic pathways and toxicology studies, providing insights into lipid metabolism and potential cellular effects of phthalate exposure. Its properties make it valuable for investigating the biochemical impacts of hydroxy fatty acids in various biological systems.

Cat. No.

A72365

CAS No.

122068-08-0

cis-4,10,13,16-Docosatetraenoic acid

Cis-4,10,13,16-Docosatetraenoic acid is a long-chain polyunsaturated fatty acid that targets lipid metabolism. This compound is involved in various biological processes, including cellular signaling and inflammation. Its application extends to research on membrane fluidity and the role of fatty acids in physiological and pathophysiological conditions.

Cat. No.

A72406

CAS No.

1997286-67-5

13-OAHSA

Synonyms: 9Z-Octadecenoic acid; 12-carboxy-1-pentyldodecyl ester

13-OAHSA is a fatty acid ester of hydroxy fatty acids (FAHFA) that targets glucose metabolism. This compound enhances glucose-stimulated insulin secretion (GSIS) under high glucose conditions. Its ability to modulate insulin release makes it a valuable reagent for studying metabolic pathways and potential therapeutic applications in diabetes research.

Cat. No.

A72425

CAS No.

1002-96-6

Cetoleic acid

Cetoleic acid is a long-chain monounsaturated fatty acid that primarily targets lipid metabolism. It has been shown to promote the synthesis of alpha-linolenic acid (ALA) in human HepG2 cells and eicosapentaenoic acid (EPA) in salmon liver cells, influencing cholesterol levels in rodent models. This compound holds potential for applications in cardiovascular disease research, providing insights into lipid regulation and heart health.

Cat. No.

A72429

CAS No.

68378-49-4

Nisinic acid

Synonyms: C24:6n-3

Nisinic acid (C24:6n-3) is a very long chain polyunsaturated fatty acid (VLCPUFA) known for its role in lipid metabolism. It is a key component of triglycerides and cholesterol esters, particularly in murine testicular tissues. Research applications include studies on reproductive biology and lipid composition, making it valuable for investigations into cellular signaling and metabolic processes involving VLCPUFAs.

Cat. No.

A72470

CAS No.

24880-40-8

ω-3 Arachidonic acid

ω-3 Arachidonic acid is a polyunsaturated fatty acid known for its important role in growth and development, particularly in infants. This compound inhibits arachidonyl-CoA synthetase with a Ki value of 14 µM and demonstrates inhibition of arachidonyl-CoA synthetase in calf brain extract with an IC50 of approximately 5 µM. It is useful for research applications focusing on fatty acid metabolism and related neurological processes.

Cat. No.

A72488

CAS No.

17773-30-7

3-Hydroxystearic acid

3-Hydroxystearic acid is a long-chain saturated fatty acid known for its role in lipid metabolism. It demonstrates various biological activities, including potential anti-inflammatory properties. This compound is utilized in research applications related to metabolic studies and the investigation of fatty acid synthesis pathways.

Cat. No.

A72521

CAS No.

4158-12-7

10-Oxooctadecanoic acid

10-Oxooctadecanoic acid is an oxo fatty acid known for its role in adipocere formation. It is associated with the stabilization and enhancement of adipocere, particularly in human remains that have been deceased for extended periods. This compound is valuable in forensic science and biochemical research focused on the decomposition process and fatty acid metabolism.

Cat. No.

A72587

CAS No.

84494-72-4

Ethyl docosa-4,7,10,13,16,19-hexaenoate

Ethyl docosa-4,7,10,13,16,19-hexaenoate is the ethyl ester of docosahexaenoate (DHA), a prominent omega-3 fatty acid. This compound plays a crucial role in various biological processes, including inflammation modulation and neuronal health. Its applications extend to research in cardiovascular and neurodegenerative diseases, making it a valuable reagent for studies requiring the analysis of lipid metabolism and the effects of omega-3 fatty acids on cellular functions.

Cat. No.

A72616

CAS No.

70968-93-3

(±)8-HETE

Synonyms: 8-Hydroxy-5(Z),9(E),11(Z),14(Z)-eicosatetraenoic acid

(±)8-HETE is a monohydroxy fatty acid derived from the non-enzymatic oxidation of arachidonic acid. This compound exhibits biological activities similar to its enantiomers, 8(R)-HETE and 8(S)-HETE, and plays a role in various cellular processes. Research applications include studies on fatty acid metabolism and the investigation of lipid signaling pathways.

Cat. No.

A72626

CAS No.

617-31-2

2-Hydroxyvaleric acid

2-Hydroxyvaleric acid is an α-hydroxy fatty acid that serves as a key activator in the metabolism of palmitic acid-1-C14. This compound is utilized in research to measure tissue-specific lactate dehydrogenase activity, acting as an effective staining agent. Elevated concentrations of 2-hydroxyvaleric acid can induce lactic acidosis, making it relevant for studies examining metabolic dysregulation and related pathologies.

Cat. No.

A72642

CAS No.

73347-43-0

11(R)-HETE

11(R)-HETE is a hydroxy fatty acid derived from arachidonic acid, functioning primarily as a signaling molecule. It plays a crucial role in various physiological processes, including inflammation and cellular signaling. This compound is utilized in research applications focused on lipid metabolism, inflammation pathways, and the study of eicosanoid biology.

Cat. No.

A72782

CAS No.

1264-57-9

Decanoyl coenzyme A

Synonyms: Decanoyl-coa

Decanoyl coenzyme A is a key primer for the fatty acid elongation system in Mycobacterium smegmatis. It plays a crucial role in the biosynthesis of long-chain fatty acids, which are essential for cellular structures and functions. This reagent is valuable for studying fatty acid metabolism, cellular envelope integrity, and lipid biosynthesis pathways in various biological research contexts.

Cat. No.

A72831

CAS No.

98524-19-7

(±)9-HODE

(±)9-HODE is a racemic mixture of 9-hydroxy-octadecadienoic acid (9-HODE), an oxidized derivative of linoleic acid. This compound is known to play a role in various biological processes, including inflammation and cellular signaling. Its potent biological activity makes (±)9-HODE a valuable reagent for research applications focused on lipid metabolism, oxidative stress, and related signaling pathways.

Cat. No.

A72838

CAS No.

503-06-0

Phytomonic acid

Phytomonic acid is a long-chain fatty acid featuring a cyclopropane ring and is derived from Lactobacillus reuteri. It possesses the unique ability to modulate immune responses by resisting tumor necrosis factor-alpha (TNF-α). This compound is of interest in research applications related to inflammation and immune regulation, making it a valuable tool for studying host-microbe interactions and potential therapeutic strategies.

Cat. No.

A72868

CAS No.

2126038-97-7

13-POHSA

13-POHSA is a fatty acid ester of hydroxy fatty acids (FAHFAs) that enhances glucose-stimulated insulin secretion (GSIS) under high glucose conditions. This compound plays a critical role in glucose metabolism and insulin regulation, making it valuable for research in diabetes and metabolic disorders. Its mechanism of action and biological activity provide insight into potential therapeutic approaches for improving insulin sensitivity and managing glucose levels.

Cat. No.

A73034

CAS No.

51350-61-9

12-SAHSA

12-SAHSA is a fatty acid ester that targets fatty acid hydroxy fatty acids (FAHFAs). It has been shown to decrease levels in human serum associated with breast cancer. This compound is employed in research focused on the mechanisms of cancer metabolism and potential therapeutic strategies for breast cancer treatment.

Cat. No.

A73036

CAS No.

873108-81-7

4(Z),7(Z),10(Z),13(Z)-Hexadecatetraenoic acid methyl ester

4(Z),7(Z),10(Z),13(Z)-Hexadecatetraenoic acid methyl ester is a polyunsaturated fatty acid ester that primarily targets lipid metabolism and cellular signaling pathways. It exhibits potential anti-inflammatory and anticancer properties, making it a valuable tool for cancer research and studies on lipid-related diseases. This compound is useful in investigating the role of fatty acids in cellular processes and therapeutic strategies.

Cat. No.

A73051

CAS No.

163860-24-0

Sanleng acid

Sanleng acid is an unsaturated fatty acid derived from the hexane extract of Magnolia sieboldii. It exhibits anti-inflammatory activity by inhibiting the expression of inflammatory mediators, such as COX-2, and pro-inflammatory cytokines, including TNF-α and IL-1β. Additionally, Sanleng acid enhances the expression of tight junction proteins (claudin-4 and claudin-5), thereby supporting epithelial barrier function. This compound is relevant for research on conditions such as reflux esophagitis.

Cat. No.

A73176

CAS No.

852043-48-2

Tetradecyl-CoA triammonium

Tetradecyl-CoA triammonium is a long-chain acyl-CoA molecule that serves as a key substrate in fatty acid metabolism. This compound plays a critical role in various metabolic pathways, including lipid biosynthesis and energy production. It is commonly utilized in research applications investigating acyl-CoA signaling mechanisms and the regulation of fatty acid oxidation.

Cat. No.

A73354

CAS No.

2042646-31-9

12-POHSA

12-POHSA is a fatty acid ester of hydroxy fatty acids (FAHFAs) that targets metabolic pathways involved in glucose homeostasis. This compound enhances glucose-stimulated insulin secretion (GSIS) in the presence of elevated glucose levels, making it a valuable tool for studying insulin signaling and beta-cell function. Its potential applications include research into diabetes and related metabolic disorders.

Cat. No.

A73374

CAS No.

1895916-79-6

9-SAHSA

9-SAHSA is a fatty acid ester derived from hydroxy fatty acids (FAHFAs) that targets colon carcinoma cells. It exhibits protective properties by preventing apoptotic cell death, making it a valuable reagent for cancer research. Its mechanism of action provides insights into the cellular processes underlying colon cancer progression and potential therapeutic interventions.

Cat. No.

A73503

CAS No.

99217-78-4

11-HEPE

11-HEPE is a monohydroxy fatty acid that is derived from eicosapentaenoic acid (EPA). It exhibits anti-inflammatory properties and plays a role in modulating immune response. This compound is utilized in research related to metabolic disorders, cardiovascular health, and inflammation, making it a valuable tool for investigating the effects of fatty acid metabolites in biological systems.

Cat. No.

A73511

CAS No.

156473-26-6

11(S)-HEPE

11(S)-HEPE is a monohydroxy fatty acid derived from eicosapentaenoic acid (EPA). This compound exhibits anti-inflammatory properties and plays a crucial role in the resolution of inflammation. It is utilized in research to explore its potential therapeutic applications in inflammatory diseases and to study lipid mediator pathways.