Fatty Acids & Derivatives

Cat. No.

A74472

CAS No.

10018-93-6

(2E)-Hexenoyl-CoA

Synonyms: Hex-2-trans-enoyl-CoA

(2E)-Hexenoyl-CoA is an important intermediate in fatty acid metabolism, primarily functioning as a substrate for various enzymatic activities. It is utilized by enzymes such as enoyl-coenzyme A reductase, acyl-CoA oxidase, acyl-CoA dehydrogenase, long-chain-acyl-CoA dehydrogenase, and oxidoreductases. This compound is essential for understanding metabolic pathways related to lipid metabolism and energy production. Researchers can employ (2E)-Hexenoyl-CoA in studies aimed at delineating the roles of these enzymes in metabolic regulation and fatty acid catabolism.

Cat. No.

A74476

CAS No.

2169306-42-5

13-PAHSA

13-PAHSA is a branched fatty acid ester of hydroxy fatty acids (FAHFAs) that serves as an endogenous lipid. It exhibits anti-inflammatory properties and has been shown to enhance insulin sensitivity, making it a valuable tool for research into metabolic disorders. Its role in modulating metabolic processes provides insight into the therapeutic potential for conditions such as obesity and diabetes.

Cat. No.

A74478

CAS No.

191545-08-1

12(Z),15(Z)-Heneicosadienoic acid

12(Z),15(Z)-Heneicosadienoic acid is a polyunsaturated fatty acid that plays a significant role in cellular metabolism and membrane fluidity. This compound has been studied for its potential anti-inflammatory effects and its involvement in lipid signaling pathways. Research applications include investigations into fatty acid metabolism, cardiovascular health, and its influence on cellular processes.

Cat. No.

A74496

CAS No.

1417651-32-1

(9E,11E)-9-Nitro-9,11-octadecadienoic acid

Synonyms: 9E,11E-9-Nitro CLA

(9E,11E)-9-Nitro-9,11-octadecadienoic acid (9E,11E-9-Nitro CLA) is a nitro-fatty acid that is synthesized through the reaction of 9Z, 11E-CLA with acidified nitrite, peroxynitrite, or nitrogen dioxide, as well as through the action of myeloperoxidase in the presence of hydrogen peroxide and nitrite. This compound demonstrates significant biological activity as a modulator of inflammation and cellular signaling pathways. Its applications in research include studies on cardiovascular health, metabolic disorders, and the role of nitro-fatty acids in various physiological processes.

Cat. No.

A74512

CAS No.

2270844-02-3

10(R)-PAHSA

10(R)-PAHSA is a stereoisomer of 10-PAHSA, an endogenous lipid classified as a branched fatty acid ester of hydroxy fatty acids (FAHFAs). This compound exhibits anti-inflammatory properties and plays a significant role in metabolic regulation, making it valuable for research in obesity, diabetes, and cardiovascular diseases. Its unique mechanism of action offers insights into lipid signaling and potential therapeutic targeting in lipid-related disorders.

Cat. No.

A74546

CAS No.

929-79-3

Δ2-trans-Hexadecenoic acid

Δ2-trans-Hexadecenoic acid is a trans fatty acid primarily recognized for its ability to influence cellular lipid metabolism. It is derived from the seed oil of Aster tataricus (Thunb.) and has been implicated in various biological processes. This compound serves as a valuable tool in research focusing on the effects of trans fatty acids on health, metabolism, and chronic disease pathways.

Cat. No.

A74556

CAS No.

2108907-29-3

13-SAHSA

Synonyms: 13-[(1-Oxooctadecyl)oxy]-octadecanoic acid

13-SAHSA is an endogenous lipid that acts as a branched fatty acid ester of hydroxy fatty acids (FAHFAs). It is involved in various biological processes, including modulation of inflammation and regulation of metabolism. 13-SAHSA exhibits significant potential in research applications focusing on lipid metabolism, metabolic disorders, and inflammatory diseases.

Cat. No.

A74630

CAS No.

861891-72-7

PDP-EA

PDP-EA is an active compound that enhances the amidohydrolase activity of fatty acid amide hydrolase (FAAH). This modulation of FAAH activity has implications for research in pain management, anxiety disorders, and inflammation pathways. PDP-EA can be utilized in studies exploring the biochemical effects of altered endocannabinoid signaling and lipid metabolism.

Cat. No.

A74664

CAS No.

1450603-63-0

FAAH inhibitor 2

FAAH Inhibitor 2 is an irreversible inhibitor of fatty acid amide hydrolase (FAAH), demonstrating an IC50 of 0.153 μM. This compound is essential for studies evaluating endocannabinoid signaling pathways and the modulation of pain and inflammation. Its application in research aids in understanding the therapeutic potential of FAAH inhibition in various physiological and pathological states.

Cat. No.

A76034

CAS No.

1849616-54-1

6-Oxohexyl 2-hexyldecanoate, 80% (ELSD)

6-Oxohexyl 2-hexyldecanoate is a lipid-based compound involved in synthesizing the novel drug delivery system ALC-0315. This reagent exhibits potential biological activity in enhancing the delivery of therapeutic mRNA, making it valuable for research focused on advanced drug delivery methods. Its applications extend to studies in lipid formulations and nanocarrier systems for gene therapy.

Cat. No.

A76053

CAS No.

240125-70-6

11-Mercaptoundecanoate-NHS

11-Mercaptoundecanoate-NHS is a lipid-based reagent that functions as an NHS (N-hydroxysuccinimide) ester, facilitating the synthesis of linkers for bioconjugation applications. Its primary mechanism involves the conjugation of biomolecules through amine-reactive chemistry, making it valuable for the development of targeted drug delivery systems and biotechnological research. This reagent is instrumental in creating stable linkages that enhance the efficacy and specificity of therapeutic agents.

Cat. No.

A76133

CAS No.

1566559-80-5

Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate

Synonyms: 304O13

Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate is a biodegradable lipid that serves as an effective carrier for polynucleotide delivery. This compound facilitates the encapsulation and transport of RNA molecules, including siRNA, enhancing their stability and cellular uptake. Its applications extend to various drug delivery systems, making it a valuable reagent for research in gene therapy and RNA therapeutics.

Cat. No.

A76264

CAS No.

2644752-88-3

6-((4-Hydroxybutyl)amino)hexyl 2-hexyldecanoate

6-((4-Hydroxybutyl)amino)hexyl 2-hexyldecanoate is a lipid-based compound that plays a crucial role in the synthesis of nanomaterials. This molecule is particularly valuable in the formulation of nano-lipid particles, which serve as essential components for effective nucleic acid delivery systems. Its unique structure enhances the stability and functionality of delivery carriers, facilitating targeted therapeutic applications in gene editing and RNA delivery research.

Cat. No.

A76298

CAS No.

2832061-33-1

Piperazine-bis(ethyl octadeca-9,12-dienoate)

Piperazine-bis(ethyl octadeca-9,12-dienoate) acts as a cationic lipid, facilitating the formation of lipid nanoparticles (LNPs). It is particularly useful in pharmaceutical research for the delivery of nucleic acids and other biomolecules, enhancing transfection efficiency. Its unique properties make it suitable for developing targeted drug delivery systems and gene therapy applications.

Cat. No.

A76314

CAS No.

1849616-53-0

Decanoic acid, 2-hexyl-, 6-oxohexyl ester-1

Decanoic acid, 2-hexyl-, 6-oxohexyl ester-1 is a lipid-based compound that facilitates drug delivery through enhanced lipid solubility and improved permeability. This ester derivative is useful in the formulation of lipid-based drugs, enabling efficient transport of therapeutic agents across biological membranes. Its unique structure promotes stability and bioavailability, making it a valuable tool in pharmaceutical research and development.

Cat. No.

A76417

CAS No.

86282-92-0

15(S)-HEPE

Synonyms: 15(S)-hydroxy-Eicosapentaenoic acid; 15(S)-hydroxy EPA

15(S)-HEPE is a monohydroxy fatty acid synthesized from eicosapentaenoic acid by the enzyme 15-lipoxygenase (15-LO). This compound has been identified as a potential biomarker for asthma, with elevated serum levels observed in patients suffering from this condition. It serves as a valuable tool in understanding the underlying mechanisms of asthma and for the development of therapeutic strategies targeting airway inflammation.

Cat. No.

A76427

CAS No.

71606-07-0

(9S,13R)-12-Oxo phytodienoic acid

Synonyms: (9S,13R)-12-OPDA

(9S,13R)-12-Oxo phytodienoic acid is a key oxylipin involved in plant signaling, specifically as a lipoxygenase metabolite found in the foliage of green plants. This compound plays a crucial role in mediating stress responses and developmental processes in plants. It is utilized in research applications focusing on plant biology, particularly in studies examining the biosynthesis of fatty acid derivatives and their effects on plant growth and adaptation to environmental stimuli.

Cat. No.

A76447

CAS No.

118492-81-2

8(S)-HEPE

8(S)-HEPE is a monohydroxy fatty acid derived from the lipoxygenase-mediated oxidation of eicosapentaenoic acid (EPA). This compound has been shown to stimulate the hatching of barnacle eggs at concentrations as low as 10 nM, although its role as a natural egg hatching factor is not definitively established. 8(S)-HEPE is useful for studying the biochemical pathways involving monohydroxy fatty acids and their biological activities.

Cat. No.

A86829

CAS No.

1731-94-8

Methyl nonadecanoate

Methyl nonadecanoate is an internal standard commonly employed in the quantification of fatty acid methyl esters (FAMEs) in biodiesel analysis. Its stable chemical structure enhances accuracy in the measurement of FAME content, making it an essential reagent for researchers in the fields of biofuel production and lipid analysis. This compound facilitates reliable data interpretation by serving as a reference point in chromatographic techniques.

Cat. No.

A87457

CAS No.

88-09-5

2-Ethylbutyric acid

2-Ethylbutyric acid is a volatile fatty acid that primarily targets biological systems involved in metabolic processes. It demonstrates phytotoxic properties and serves as an internal standard in the analysis of milk, dairy products, and fecal volatile fatty acids. Additionally, 2-Ethylbutyric acid is utilized in research related to embryonic development, making it a valuable reagent in various biochemical studies.

Cat. No.

A87628

CAS No.

98063-21-9

(R)-Aminocarnitine

Synonyms: Emeriamine

(R)-Aminocarnitine is an established inhibitor of fatty acid oxidation, demonstrating potential efficacy in reducing hyperglycemia and ketosis. This compound is valuable for research involving metabolic diseases, providing insights into metabolic dysregulation and potential therapeutic interventions. Its mechanism of action makes it a significant tool for studying the biochemical pathways involved in energy metabolism.

Cat. No.

A87630

CAS No.

29743-97-3

cis-10-Heptadecenoic acid

Cis-10-Heptadecenoic acid is a cis-fatty acid that serves as a substrate for the synthesis of polyhydroxy-chain alkanoates, mediated by enzymes such as 2,4-dienyl-CoA reductase and Delta3, Delta2-enyl-CoA isomerase. This compound plays a significant role in lipid metabolism and may be utilized in research focused on fatty acid biosynthesis, bioengineering of microbial systems, and the development of bioplastics. Its unique structural properties make it a valuable reagent for studies in lipid biochemistry and metabolic engineering applications.

Cat. No.

A88019

CAS No.

84743-29-3

10(Z)-Pentadecenoic acid

Synonyms: cis-10-Pentadecenoic acid

10(Z)-Pentadecenoic acid is an unsaturated fatty acid characterized by a double bond in its structure. As a key lipid molecule, it plays a significant role in various biological processes, including membrane fluidity and signaling. This compound is useful in research applications focusing on lipid metabolism, cell membrane dynamics, and the study of fatty acid derivatives in physiological functions.

Cat. No.

A88079

CAS No.

82426-88-8

3-(Octanoyloxy)propane-1,2-diyl bis(decanoate)

3-(Octanoyloxy)propane-1,2-diyl bis(decanoate) is a triglyceride compound that serves as a lipid-based model for biochemical studies. This reagent is crucial for investigating lipid metabolism, membrane dynamics, and cellular lipid storage. It is widely applied in research focused on obesity, energy homeostasis, and metabolic diseases.

Cat. No.

A88085

CAS No.

1841512-95-5

17-Azidoheptadecanoic acid

17-Azidoheptadecanoic acid is a fatty acid azide featuring an azide linker that enables its participation in copper-catalyzed click chemistry reactions. This reagent facilitates the selective modification of proteins through reactions with alkynes, dibenzocyclooctyne (DBCO), and bicyclo[6.1.0]nonyne (BCN). Its utility in bioconjugation and labeling applications makes it a valuable tool for researchers in chemical biology and proteomics.