Phospholipids

Cat. No.

A72153

CAS No.

326495-24-3

1-Oleoyl-2-hydroxy-sn-glycero-3-PG sodium

Synonyms: 18:1 Lyso-PG; 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol); 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoglycerol

1-Oleoyl-2-hydroxy-sn-glycero-3-PG sodium is a lysophospholipid that targets phospholipids with oleic acid (18:1) incorporated at the sn-1 position. This compound is instrumental in the formation of micelles, liposomes, and various artificial membrane systems, making it valuable for lipid-based drug delivery research. Its unique structure facilitates the exploration of membrane dynamics and cellular interactions.

Cat. No.

A72239

CAS No.

174062-73-8

C18(Plasm) LPE

Synonyms: PE(18:1p/0:0)

C18(Plasm) LPE, or PE(18:1p/0:0), is a bioactive lipid that plays a crucial role in cell signaling pathways and promotes cellular proliferation. This compound can be utilized in research applications focused on lipid metabolism, cell growth regulation, and the modulation of signaling networks. Its unique properties make it an important tool for investigating the biochemical processes associated with lipid-mediated cellular functions.

Cat. No.

A72265

CAS No.

124262-93-7

18:0,18:1 PS

18:0,18:1 PS is a phosphatidylserine subtype that plays a crucial role in cellular membranes, particularly in the brain, exosomes, and HIV particles. This compound is essential for maintaining membrane integrity, lipid raft organization, and intracellular trafficking. It facilitates interleaflet membrane coupling through cholesterol-dependent interactions with very long-chain sphingolipids and promotes the clustering of glycosylphosphatidylinositol-anchored proteins. Furthermore, clusters formed by the interaction of 18:0,18:1 PS with cholesterol enhance its distribution in lipid bilayers while providing protection against oxidative damage. Research applications include studies on membrane dynamics, lipid metabolism, and the role of phospholipids in cell signaling.

Cat. No.

A72309

CAS No.

71242-28-9

13:0 PC

Synonyms: PC(13:0/13:0); DTPC

13:0 PC, also known as ditridecanoyl phosphatidyl choline (DTPC), is a phospholipid featuring a distinct structural design that consists of a positively charged quaternary amine and a negatively charged phosphate group, paired with two long-chain fatty acid tails. This compound serves as an essential component in studies involving membrane biophysics, lipid bilayer formation, and cell membrane dynamics. Its unique properties make it a valuable tool for researchers investigating membrane-associated processes and the behavior of lipid-based systems.

Cat. No.

A72825

CAS No.

1246298-16-7

18:0 Lyso PS sodium

18:0 Lyso PS sodium is a bioactive lipid that influences cell signaling pathways. It is crucial for maintaining the fluidity and structural integrity of cell membranes. This reagent is widely utilized in lipidomics research to investigate lipid metabolism and its effects on cellular functions.

Cat. No.

A72888

CAS No.

99264-98-9

1-Stearoyl-2-Eicosapentaenoyl-sn-glycero-3-PC

1-Stearoyl-2-eicosapentaenoyl-sn-glycero-3-PC is a phospholipid primarily found in human red blood cells. This compound plays a crucial role in membrane structure and fluidity, influencing various biological processes. It is commonly utilized in research applications related to cell membrane dynamics, lipid metabolism, and the study of cardiovascular health.

Cat. No.

A73009

CAS No.

2194571-25-8

1-Palmitoyl-2-formylyl PC

1-Palmitoyl-2-formylyl PC (PFPC) is a formate-containing phosphatidylcholine lipid. It serves as a valuable tool for studying lipid metabolism and membrane dynamics. PFPC is instrumental in researching cellular processes related to lipid storage, signaling pathways, and the role of lipids in cellular membranes.

Cat. No.

A73063

CAS No.

37288-19-0

Phosphatidylinositol phosphodiesterase

Phosphatidylinositol phosphodiesterase targets phosphatidylinositol, catalyzing its hydrolysis to produce diacylglycerols and a mixture of myoinositol 1-phosphates and 1,2-cyclic phosphates. This enzymatic activity plays a crucial role in cellular signaling pathways, influencing various biological processes such as lipid metabolism and signal transduction. It is a valuable reagent for studying phosphoinositide metabolism and related signaling events in biochemical research.

Cat. No.

A73477

CAS No.

22248-63-1

1-Decanoyl-sn-glycero-3-phosphocholine

Synonyms: 1-Decanoyl-2-hydroxy-sn-glycero-3-phosphatidylcholine

1-Decanoyl-sn-glycero-3-phosphocholine is a lipidic compound specifically targeting membrane phospholipids. It plays a crucial role in the structure of sperm membrane lipids and is significant for studying membrane dynamics and lipid interactions. This compound is valuable in research applications focused on reproductive biology and cellular membrane studies.

Cat. No.

A74022

CAS No.

1213783-80-2

1-Hexacosanoyl-sn-glycero-3-phosphocholine

Synonyms: 26:0 Lyso PC

1-Hexacosanoyl-sn-glycero-3-phosphocholine is a long-chain fatty acid that serves as a critical component of phospholipid membranes. This compound has been identified as a potential biomarker for X-linked adrenoleukodystrophy (ALD) in murine models. Its role in lipid metabolism and cell signaling makes it a valuable tool in studying metabolic disorders and neurodegenerative diseases. Researchers can utilize this reagent to investigate the pathophysiological mechanisms associated with ALD and related conditions.

Cat. No.

A74152

CAS No.

1621962-91-1

LysoPC (18:4(6Z,9Z,12Z,15Z))

LysoPC (18:4(6Z,9Z,12Z,15Z)) is a lysophosphatidylcholine derivative that incorporates stearidonic acid, targeting lipid signaling pathways. This compound demonstrates significant potential in mediating cell membrane dynamics and may enhance the delivery of therapeutic agents across the blood-retinal barrier via the Mfsd2a transporter. It serves as a valuable tool in studying neurodegenerative diseases and retinal disorders, facilitating research into lipid metabolism and signaling mechanisms in various biological systems.

Cat. No.

A74290

CAS No.

802981-98-2

PE(P-16:0/18:2(9Z,12Z))

Synonyms: PlsEtn 16:0/18:2

PE (P-16:0/18:2(9Z,12Z)) is a phosphatidylethanolamine that serves as a potential metabolic biomarker for assessing uterine muscle layer infiltration and the progression of Alzheimer's disease. Its unique fatty acid composition may play a critical role in membrane dynamics and cellular signaling pathways. This reagent is valuable in research applications focused on metabolic disorders and neurodegenerative diseases.

Cat. No.

A74313

CAS No.

85082-02-6

Phosphatidylcholine (C18:2,C20:4)

Phosphatidylcholine (C18:2,C20:4) is a phospholipid primarily involved in membrane structure and function. It plays a crucial role in cell signaling and lipid metabolism. This compound is widely utilized in biological and biochemical research, particularly in studies focused on membrane dynamics, cell proliferation, and the modulation of cellular responses.

Cat. No.

A74322

CAS No.

132196-28-2

1-O-Hexadecyl-2-eicosapentaenoyl-SN-glycero-3-phosphocholine

1-O-Hexadecyl-2-eicosapentaenoyl-SN-glycero-3-phosphocholine is a specialized phospholipid that plays a crucial role in membrane structure and function. This compound exhibits significant biological activity by influencing membrane fluidity and signaling processes in cells. It is utilized in research applications pertaining to lipid metabolism, cell membrane studies, and the investigation of lipid-based therapeutics.

Cat. No.

A74458

CAS No.

86288-11-1

1-O-Hexadecyl-2-arachidonoyl-sn-glycero-3-PC

Synonyms: 16:0e/20:4-GPC

1-O-Hexadecyl-2-arachidonoyl-sn-glycero-3-PC is an alkylether-glycerophosphocholine that functions as a bioactive lipid mediator. This compound exhibits important biological activities, including modulation of cell signaling pathways and membrane dynamics. It is primarily utilized in research applications related to lipid metabolism, cellular communication, and inflammation studies.

Cat. No.

A75947

CAS No.

26853-31-6

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC

Synonyms: POPC

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC) is a phospholipid that plays a crucial role in the structure and function of biological membranes. This compound is commonly utilized in liposome preparation and serves as an important tool for investigating the characteristics of lipid bilayers. Its applications extend to membrane biophysics, drug delivery systems, and the study of membrane-protein interactions.

Cat. No.

A75956

CAS No.

18194-24-6

Colfosceril miristate

Synonyms: DMPC; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine; Dimyristoyl phosphatidylcholine

Colfosceril miristate is a synthetic phospholipid known for its role in forming lipid bilayers and monolayers. It exhibits antiproliferative effects on various tumor cell lines, making it valuable in cancer research. This compound is commonly utilized in studies related to drug delivery systems and membrane biophysics, providing insights into lipid interactions and cellular processes.

Cat. No.

A75970

CAS No.

26662-94-2

1-Palmitoyl-2-oleoyl-sn-glycero-3-PE

Synonyms: 1,2-POPE; 16:0-18:1 PE

1-Palmitoyl-2-oleoyl-sn-glycero-3-PE is a phosphatidylethanolamine (PE) lipid that targets lipid bilayers to facilitate the formation of hexagonal phase (HII) structures in acidic environments and promote membrane fusion. Its primary biological activity includes enhancing the endosomal escape of lipid nanoparticles (LNPs), thereby improving the delivery efficiency of nucleic acid therapeutics such as mRNA. This compound is particularly valuable in research applications focused on gene therapy and the development of mRNA vaccines, serving as an effective LNP carrier for targeted cellular delivery.

Cat. No.

A75972

CAS No.

97281-48-6

Hydrogenated soya phosphatidylcholine

Synonyms: HSPC; Hydrogenated soybean phosphatidylcholine

Hydrogenated soya phosphatidylcholine primarily targets phosphatidylcholine and functions as a natural phospholipid. This compound is known to enhance drug release profiles, improving the loading efficiency and solubility of water-soluble drugs for oral drug delivery applications. It is widely utilized in pharmaceutical formulations to optimize bioavailability and ensure sustained release.

Cat. No.

A75977

CAS No.

474922-82-2

DMPE-PEG2000 ammonium

Synonyms: 14:0 PEG2000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium

DMPE-PEG2000 ammonium is a PEG-phospholipid conjugate utilized in the formulation of nanostructured lipid carriers. This compound facilitates the development of lipid-based drug delivery systems, enhancing the solubility and bioavailability of hydrophobic therapeutics. Its applications extend to enabling targeted delivery and improving the pharmacokinetics of various pharmaceutical agents.

Cat. No.

A75978

CAS No.

1360858-99-6

DSPE-Mal

DSPE-Mal is a phospholipid compound featuring a maleimide reactive group. This molecule comprises two saturated fatty acid chains, allowing it to self-assemble in aqueous environments to form lipid bilayers. DSPE-Mal is primarily utilized in the preparation of liposomes, serving as nanocarriers for the delivery of active compounds in various biological research applications.

Cat. No.

A75983

CAS No.

56421-10-4

SOPC

Synonyms: PC(18:0/18:1); 2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine

SOPC, an asymmetrical phospholipid, features a saturated fatty acid (stearic acid/18:0) at the sn-1 position and an unsaturated fatty acid (oleic acid/18:1) at the sn-2 position. This compound is essential for investigating membrane dynamics, lipid bilayer formation, and cellular interactions. Its unique structure makes it suitable for various biochemical studies, including lipid metabolism and signaling pathways.

Cat. No.

A75985

CAS No.

207131-40-6

DPhPC

DPhPC is a phospholipid compound known for its exceptional mechanical and chemical stability, as well as its broad temperature phase stability and high electrical resistance. This compound readily forms unilamellar vesicles and solid-supported bilayers, making it ideal for applications in nanoliposomal drug delivery systems. DPhPC serves as an effective model membrane material for researching membrane proteins and ion channels, facilitating insights into membrane dynamics and interactions.

Cat. No.

A75992

CAS No.

7266-53-7

18:0-18:2 PE

Synonyms: 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine

18:0-18:2 PE is a phosphatidylethanolamine (PE) derivative that plays a critical role in phospholipid metabolism and is linked to various diseases, including ovarian cancer. This lipid is primarily utilized in drug delivery systems due to its biocompatibility and ability to enhance cellular uptake of therapeutic agents. Additionally, 18:0-18:2 PE is valuable in food science for improving flavor profiles, particularly in aquatic products, as well as in medical research focusing on the implications of phospholipid metabolism in disease processes.

Cat. No.

A76002

CAS No.

325171-59-3

24:0 Lyso PC

24:0 Lyso PC is a lysophospholipid (LyP) that plays a pivotal role in cell membrane dynamics and signaling. This compound exhibits potential in enhancing mRNA drug delivery systems, making it valuable for therapeutic applications in gene therapy and vaccine development. Researchers can utilize 24:0 Lyso PC to investigate its role in lipid metabolism and cellular response mechanisms.