Antibiotic

Cat. No.

A46369

CAS No.

1380078-95-4

Plazomicin sulfate

Synonyms: ACHN 490 sulfate

Plazomicin sulfate is a semi-synthetic aminoglycoside antibiotic that primarily targets bacterial ribosomes to disrupt protein synthesis. It functions as a substrate for aminoglycoside acetyltransferase and aminoglycoside phosphotransferase while remaining unmodified by several common aminoglycoside-modifying enzymes. Plazomicin sulfate exhibits selective inhibition of MATE2-K and demonstrates significant efficacy against multidrug-resistant bacteria, including carbapenem-resistant Enterobacterales. This compound is valuable for research applications focusing on antibiotic resistance and the mechanisms of action of aminoglycosides.

Cat. No.

A46882

CAS No.

162478-50-4

Aurantimycin A

Aurantimycin A is a depsipeptide antibiotic that targets Gram-positive bacteria, demonstrating potent antimicrobial activity. As a substrate of the LieAB transporter, it facilitates the study of bacterial resistance mechanisms and transporter functions. This compound is valuable for research in antibiotic development and microbial pathogenesis.

Cat. No.

A47768

CAS No.

80394-72-5

Oxanosine

Oxanosine is an antibiotic derived from the Streptomyces MG265-CF34 strain, exhibiting notable anti-tumor properties. This compound functions as a substrate for adenosine deaminase, highlighting its potential utility in various research applications related to microbial activity and cancer treatment. Its unique biochemical interactions make it a valuable reagent for studies in antibiotic development and tumor biology.

Cat. No.

A48377

CAS No.

3577-01-3

Cefaloglycin

Synonyms: Cephaloglycin

Cefaloglycin is a nephrotoxic β-lactam cephalosporin antibiotic that exhibits significant antibacterial activity, specifically targeting Gram-positive cocci, excluding enterococci. Its mechanism involves inhibition of bacterial cell wall synthesis, making it effective in clinical settings requiring treatment of specific bacterial infections. Additionally, Cefaloglycin has been shown to interfere with mitochondrial substrate uptake and respiration, adding to its profile as a compound of interest in biochemical and pharmacological research.