Fungal

Antifungal compounds in Fungal act on fungal membranes, ergosterol synthesis and other targets in yeasts and molds. Ergosterol is the main sterol of fungal membranes, so its synthesis pathway is the most common antifungal target. Azoles such as fluconazole, miconazole and oxiconazole inhibit lanosterol 14α-demethylase, a cytochrome P450 enzyme needed for ergosterol synthesis. Terbinafine and liranaftate inhibit squalene epoxidase at an earlier step of the same pathway. The morpholine amorolfine blocks later steps of ergosterol synthesis, while the polyene natamycin binds ergosterol itself. Thiabendazole, a benzimidazole, is also listed for fungal and parasitology research.

3 Items

  • UDP-rhamnose
    Cat. No.
    A33189

    UDP-rhamnose

    UDP-rhamnose is the activated form of rhamnose that plays a crucial role in the synthesis of rhamnose-containing glycans in fungi. This nucleotide sugar acts as a key substrate for glycosyltransferases, enabling the assembly of polysaccharides involved in the fungal cell wall. UDP-rhamnose is utilized in research focused on understanding fungal pathogenesis and the development of therapeutics for fungal infections.

    1 mg
    $90.00
    5 mg
    $220.00
    All 2 sizes
  • VLPA-GlcNAc
    Cat. No.
    A89708

    VLPA-GlcNAc

    VLPA-GlcNAc is a chromogenic glucosaminide substrate that serves as a valuable tool for the identification of Candida species. It can be utilized in the preparation of specialized agar media, facilitating the differentiation of Candida strains based on their enzymatic activity. This reagent is essential in microbiological research and diagnostics, particularly in clinical settings where rapid identification of fungal pathogens is crucial.

    Out of stock

    All 3 sizes
  • 5-Bromo-4-chloro-3-indolyl-α-D-maltotrioside
    Cat. No.
    A91421

    5-Bromo-4-chloro-3-indolyl-α-D-maltotrioside

    5-Bromo-4-chloro-3-indolyl-α-D-maltotrioside functions as a sensitive enzyme substrate with chemiluminescent properties. It facilitates the detection of various enzymatic activities, making it suitable for diagnostic assays aimed at identifying bacterial and fungal infections, as well as other diseases. Its utility in research applications enhances the reliability of assays in clinical microbiology and molecular diagnostics.

    Out of stock

    All 3 sizes

3 Items

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