Catalog No.
Product Name
Application
Product Information
Citations
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Detergent Agent
Dodecylphosphocholine is a detergent agent primarily used to solubilize membrane proteins for nuclear magnetic resonance (NMR) studies. Its amphiphilic characteristics facilitate the stabilization of proteins in solution, allowing for detailed analysis of their structure and dynamics. This reagent is essential for researchers investigating membrane protein function and interactions within biological membranes. -
Biochemical Assay Reagent
Perylene is a polycyclic aromatic hydrocarbon consisting of four fused benzene rings, known for its role as a biochemical assay reagent. Its unique rigid planar structure imparts distinct electronic and optical properties, facilitating applications in biochemistry, materials science, and the development of fluorescent probes. Additionally, Perylene is utilized as a photosensitizer in solar cells, making it valuable for research in various fields including material development and photonics. -
Biochemical Reagent
Ir(cod)Cl]2 is a key biochemical reagent that acts as a source of iridium in various organic transformations. This compound is essential for applications in catalysis, including cross-coupling reactions and other synthetic processes in life science research. Its ability to facilitate reactions involving a variety of substrates makes it a valuable resource for chemists exploring novel synthetic pathways. -
Biochemical Assay Reagents
Anhydrous stannous chloride, 98% is a biochemical assay reagent known for its genotoxicity, mutagenicity, and ability to induce mitotic recombination and reactive oxygen species generation. This compound is utilized in various biological research applications, including studies on DNA damage and mechanisms of mutagenesis. It serves as a critical tool for investigating the effects of oxidative stress on cellular processes and genetic stability. -
Buffer
Bis-tris propane (BTP) is a water-soluble buffering agent utilized primarily for biotechnological applications. It is particularly effective in maintaining pH stability during polymerase chain reaction (PCR) processes and can enhance the activity and stability of restriction enzymes. BTP serves as a reliable choice for various molecular biology experiments, providing optimal conditions for enzymatic reactions. -
Aldehyde Reactive Probe
Aldehyde Reactive Probe (TFA) is a biotinylated reagent designed to selectively target and label aldehyde functional groups present at apurinic/apyrimidinic (AP) sites in damaged DNA. This probe facilitates the detection and quantification of AP sites, making it essential for studies involving DNA damage and repair mechanisms. Its application is vital in genetic research, molecular biology, and the assessment of DNA integrity in various experimental contexts. -
Cell Culture Reagent
Poly-L-ornithine hydrobromide (MW 30000-70000) is a poly-lysine derivative that enhances cell adhesion in culture systems. This reagent forms a positively charged coating on cell culture vessels, providing an optimal matrix environment for cell growth. It is particularly useful for facilitating the primary culture of neurons, including dopaminergic neurons and oligodendrocytes, making it valuable for neurobiological research applications. -
Protein Crosslinker
Dimethyl pimelimidate dihydrochloride (DMP) is a versatile protein crosslinker targeting primary amines. It is commonly employed to stabilize protein-protein interactions, enhancing the efficiency of techniques such as chromatin immunoprecipitation (ChIP). DMP facilitates the analysis of protein complexes, thereby contributing to the understanding of protein functions and their roles in various biological processes. This reagent is essential for researchers investigating the dynamics of protein interactions in cellular environments. -
β-Galactosidase Substrate
4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate specifically designed for β-galactosidase assays. Upon hydrolysis, it releases p-nitrophenol, which can be quantifiably measured spectrophotometrically at 405 nm. This reagent facilitates the understanding of enzyme activity and has potential applications in research related to postmenopausal osteoporosis. Its intramolecular nucleophilic catalysis by the phosphate group at the 2-position enhances its utility in enzymatic studies. -
Biochemical Reagent
Diphenylmethanimine is a biochemical reagent utilized in various life science research applications. It acts as an organic compound and serves as a versatile building block in the synthesis of complex molecules. Its utility in laboratory settings facilitates studies involving biological materials and organic reactions. -
Zwitterionic detergent
CHAPSO is a zwitterionic detergent that effectively reduces protein adsorption. It enhances cryo-electron microscopy (cryo-EM) imaging quality and serves as a valuable reagent for the solubilization and reconstruction of membrane proteins. CHAPSO is widely used in structural studies of membrane proteins, facilitating better characterization and analysis of their structure-function relationships. -
Intermediate
Pyrroline-5-carboxylate sodium is an important intermediate in amino acid metabolism, specifically in the biosynthesis and catabolism of proline. This compound plays a significant role in cellular responses to pathogen infection and abiotic stress, facilitating research on metabolic pathways and stress response mechanisms in various organisms. Its applications extend to studies in plant biology, human health, and metabolic disorders. -
Buchwald Ligand
RuPhos is a Buchwald ligand known for its role in enhancing catalytic processes in organic synthesis. It effectively forms inactive Pd(RuPhos)2 complexes with palladium during aqueous Suzuki-Miyaura catalytic transfer polymerization, which inhibits diffusion and improves controllability of the polymerization reaction. Moreover, in anhydrous Kumada polymerization, the presence of RuPhos can lead to increased catalyst deactivation and chain transfer, thereby significantly impacting the overall control of the polymerization process. -
Biochemical Assay Reagent
Sulfobetaine-14 is a zwitterionic detergent primarily utilized as a biochemical assay reagent for the solubilization and purification of membrane-bound proteins and hydrophobic biomolecules. Its unique structure enables effective stabilization of membrane proteins in aqueous environments, making it suitable for various analytical techniques such as electrophoresis and chromatography. The long hydrocarbon chains enhance membrane penetration and solubilization capabilities, while the presence of sulfonate and quaternary ammonium groups ensures solubility and charge neutrality, facilitating the separation and analysis of diverse biomolecular species. -
Asparagine Derivative
Fmoc-Asn(Trt)-OH is a protected derivative of asparagine, featuring an Fmoc group and a trityl (Trt) protection. This reagent is essential for solid-phase peptide synthesis, facilitating the incorporation of asparagine residues into peptides. Its stability and compatibility with common peptide coupling reactions make it an important tool in peptide chemistry and related research applications. -
Biochemical Reagent
4-Formylbenzoic acid is a versatile biochemical reagent primarily used as an intermediate in the synthesis of terephthalic acid. It can react with barium carbonate to produce a two-dimensional barium(II) coordination polymer. Additionally, this compound serves as a key building block in the synthesis of acid-functionalized mesoporous silica catalysts through condensation reactions, making it valuable for various chemical research applications. -
Biochemical Reagent
Burgess reagent is a versatile biochemical reagent widely employed in organic synthesis and life science research. This compound facilitates the formation of various biologically relevant structures, enabling studies on molecular interactions and reaction pathways. Its applicability extends to diverse applications including drug development and biochemical assays. -
Phosphotyrosine-Like Substrate
4-Nitrophenyl phosphate disodium hexahydrate serves as a phosphotyrosine-like substrate and is primarily utilized in activity assays for protein tyrosine phosphatases. This colorless compound undergoes hydrolysis to yield the yellow 4-nitrophenolate ion, allowing for quantitative monitoring via absorbance at 405 nm. It is a valuable tool for researchers investigating the enzymatic activity of protein tyrosine phosphatases in various biological contexts. -
Biochemical Reagent
4-Ethynylaniline is a versatile biochemical reagent featuring an alkyne functional group that enables participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions. This compound serves as a valuable tool in click chemistry, facilitating the synthesis of complex organic molecules with azide-containing reactants. Its applications extend to both biological material research and the development of novel therapeutic agents, making it essential for various life science studies. -
Biochemical Reagent
N,O-Dimethylhydroxylamine hydrochloride serves as a biochemical reagent primarily utilized as a terminal protecting group in oligosaccharide synthesis. This compound facilitates the selective modification of hydroxyl groups, allowing for the efficient construction and manipulation of complex glycosidic structures. Its role in carbohydrate chemistry makes it an essential tool for researchers investigating glycan synthesis and modifications. -
Biochemical Assay Reagent
CM Cellulose CM-32 (Carboxymethyl cellulose) functions as a biochemical assay reagent, primarily utilized in various biomedical applications. This cellulose derivative shows significant promise in tissue engineering, wound dressing, and the creation of absorbent nonwovens, as well as in the fabrication of three-dimensional scaffolds for biocompatible implants and artificial organs. Additionally, CM Cellulose CM-32 has been demonstrated to inhibit osteoclast formation, making it valuable for research related to bone health and disease diagnosis. -
Copper Supplement Aid
Copper(II) Gluconate is a copper salt of D-gluconic acid that serves as a non-toxic copper supplement. It functions as a precursor catalyst, particularly in photo-induced polymerization processes of acrylates. This compound is valuable in biochemical research related to copper's role in enzymatic processes and may also be utilized in studies involving polymer chemistry. Its unique properties make it a versatile reagent for various applications in life science research. -
Biochemical Reagent
Tri-tert-butylphosphine tetrafluoroborate is a versatile biochemical reagent that serves as a phosphine ligand in coordination chemistry. This compound is commonly utilized in synthetic organic chemistry and catalysis, particularly in reactions involving transition metal complexes. Its ability to stabilize metal ions makes it a valuable tool in various life science research applications, including the development of novel pharmaceuticals and biological materials. -
Protease
Endoproteinase Lys-N (MS grade) is a highly specific protease that cleaves the N-terminal peptide bond of lysine residues in proteins. This enzyme plays a critical role in protein digestion and peptide mapping, making it valuable for applications in mass spectrometry and proteomics. By facilitating precise peptide sequencing, Endoproteinase Lys-N enhances the quality and accuracy of protein analysis in various research settings. -
Biochemical Reagent
BOP hexafluorophosphate is a biochemical reagent that serves as a key coupling agent in peptide synthesis, particularly in solid-phase methodologies. It facilitates the formation of amide bonds, making it essential for the stepwise synthesis of peptide fragments, such as [Ala15]-GRF(1-29)-NH2. This reagent is widely utilized in life sciences research for the development and modification of peptides and proteins. -
Biochemical Assay Reagent Control
tert-Butyl carbazate is a biochemical assay reagent utilized as a control in various biological investigations. Its primary mechanism involves serving as a source of hydrazine for the synthesis of carbazates and related derivatives, which are important in the development of nitrogen-containing compounds. This reagent is employed in assays that evaluate the reactivity of carbonyl compounds and has applications in organic synthesis and chemical biology research. -
DTT Epimer
Dithioerythritol (DTE) is a thiol reducing agent that functions as an epimer of Dithiothreitol (DTT). This sulfur-containing sugar is derived from the 4-carbon monosaccharide erythrose and is utilized in various biochemical assays to maintain protein stability by preventing oxidation. DTE is valuable in research applications involving protein folding, enzyme activity modulation, and the preservation of biomolecules in vitro. -
Biochemical Reagent
Sodium sulfite is a biochemical reagent primarily used to reduce agents in various biological applications. It plays a critical role in limiting oxidative damage and can serve as an antioxidant in experimental setups. This compound is often employed in biochemical research for the preservation of biological samples and in assays assessing sulfite metabolism. -
Nucleophilic Reagent
Meldrum's acid (2,2-Dimethyl-1,3-dioxane-4,6-dione) serves as a nucleophilic reagent, primarily utilized in Michael addition reactions. It is an important compound in organic synthesis and is also applied in asymmetric organocatalysis, aiding in the formation of chiral compounds. Its versatile reactivity and ability to act as a carbon nucleophile make it valuable for various chemical research applications. -
Cross-linking Reagent
2-(Pyridyldithio)ethylamine hydrochloride is a disulfide cross-linking reagent that facilitates the formation of covalent bonds between biomolecules. This compound is particularly useful in the study of protein interactions and stabilization, enabling researchers to investigate complex biological systems. Its unique ability to intercalate and form disulfide linkages makes it a valuable tool for biochemical and biophysical applications in chemical biology research. -
Biochemical Assay Reagent
(NH2)2bpy, or 4,4'-Diamino-2,2'-bipyridine, serves as a versatile biochemical assay reagent known for its role as a catalyst and complexing agent. This compound readily forms complexes with various metal ions and organic molecules, enhancing catalytic activity in organic synthesis reactions. Additionally, (NH2)2bpy is employed in chemical analysis techniques, including biological and electrochemical detection methods, making it valuable for diverse research applications. -
Biochemical Assay Reagent
Ac4GlcNAz, an azido-tagged analogue of N-acetylglucosamine (GlcNAc), serves as a biochemical assay reagent with a primary mechanism of action involving the hexosamine biosynthetic pathway. It is designed with azide functionality on the N-acyl side chain and is acetylated to enhance cell membrane permeability. Once inside the cell, Ac4GlcNAz is deacetylated, allowing it to participate in glycosylation processes. The resultant modified proteins can be labeled with fluorescent tags via Cu(I)-catalyzed azide-alkyne cycloaddition, facilitating detection and analysis in various research applications. -
Tumor Inducer
N,N'-Dimethylhydrazine dihydrochloride is a potent tumor inducer targeting colon cancer pathways. This compound is widely used in rodent models to study the mechanisms of tumorigenesis and cancer progression. It serves as a valuable tool in cancer research, enabling the investigation of therapeutic approaches and the assessment of potential chemopreventive agents. -
Biochemical Assay Reagent
DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic oligosaccharide that serves as a solubilizer and carrier for poorly soluble drugs, enhancing their bioavailability in pharmaceutical preparations. This compound exhibits significant ability to form inclusion complexes with various guest molecules, which is valuable in analytical chemistry, food science, and environmental remediation. Research applications include the encapsulation of aromatic compounds, pesticides, and heavy metals, demonstrating its versatility in diverse biochemical assays and formulations. -
Chelating Agent
Potassium hexacyanoferrate(III) is a chelating agent that effectively binds metal ions, particularly iron and copper. Its ability to sequester these metals makes it valuable in various biochemical and research applications, including the study of metal ion interactions and the development of metal-based assays. This reagent is instrumental in enhancing analytical sensitivity and specificity in metal detection and quantification. -
Intermediate
4-Pentynoic acid, also known as propargylacetic acid, serves as a valuable intermediate in the synthesis of biologically active compounds. Its unique alkyne functionality enables its use as a building block for generating sequence-defined model oligomers. Additionally, 4-Pentynoic acid acts as a click chemistry reagent, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, making it essential for various chemical research applications. -
Biochemical Reagent
1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester serves as a versatile biochemical reagent with applications in organic synthesis and bioconjugation. Its boronic acid functionality enables selective binding to diols, facilitating the development of novel compounds and materials. This intermediate is useful in the preparation of diverse scaffolds for drug development and probing biological pathways in life science research. -
Defoamer
Simethicone acts as an effective defoamer by reducing the surface tension of air bubbles in the gastrointestinal tract. This mechanism facilitates the expulsion of gas through vomiting, exhalation, or absorption into the bloodstream. Simethicone is primarily utilized in research related to gastrointestinal disorders, making it relevant for studies on flatulence and colic. -
Biochemical Reagent
DABCO-Bis(sulfur dioxide) (DABSO) acts as a source of sulfur dioxide, facilitating its incorporation into various organic synthesis reactions. This reagent is particularly valuable in the preparation of sulfonamides, enabling the formation of sulfonate groups. Its versatility makes it a useful tool in synthetic organic chemistry and biochemical research applications focusing on sulfur-containing compounds. -
Biochemical Assay Reagent
3,5-Dinitrosalicylic acid is a derivative of salicylic acid primarily used as a biochemical assay reagent. It serves as a colorimetric indicator for the quantification of reducing sugars and is essential in assays for α-amylase and other carbohydrases. This compound is widely utilized in carbohydrate chemistry and enzymatic activity studies, facilitating the analysis of reducing sugars in various samples. -
Biochemical Assay Reagent
DEAE-Dextran (MW 500000) is a cationic carbohydrate polymer modified with diethylaminoethyl (DEAE) groups, facilitating the transfection of nucleic acids, including DNA and RNA, into cells. Its positive charge enhances interaction with negatively charged cell membranes, promoting efficient uptake. Additionally, DEAE-Dextran serves as an ion-exchange chromatography resin, enabling the separation and purification of biomolecules based on charge properties. This reagent is widely utilized in biochemical assays and molecular biology applications. -
Biochemical Assay Reagent
Dithizone is a biochemical assay reagent primarily used for the detection and extraction of heavy metals through chelation. It forms stable colored complexes with metal ions such as lead and mercury, allowing for quantitative analysis via spectrophotometry. Additionally, Dithizone serves as a staining agent for in vitro and in vivo visualization of pancreatic islet cells and cytoplasmic granules in bone marrow cells, facilitating research in diabetes and cellular biology. -
Antitumor Agent
5-Sulfosalicylic acid dihydrate is a sulfonated derivative of salicylic acid that functions primarily as an antitumor agent. This compound exhibits significant cytotoxicity against the MCF-7 breast cancer cell line while demonstrating lower toxicity to normal cells. Additionally, 5-sulfosalicylic acid dihydrate possesses antioxidant properties, making it a valuable tool in cancer research and therapeutic investigations. -
Biochemical Reagent
4-(Trifluoromethyl)-1H-pyrazole is a biochemical reagent commonly utilized in organic synthesis and life science research. This compound serves as a versatile building block for the development of diverse chemical entities. Its unique trifluoromethyl group enhances lipophilicity, making it a valuable tool in medicinal chemistry and biological studies. Researchers can leverage its properties to explore various biochemical pathways and mechanisms. -
3-Furanoboric Acid
3-Furanboronic acid is a boronic acid compound that functions primarily as a coupling agent in Suzuki-Miyaura cross-coupling reactions. It demonstrates efficient reactivity with a variety of halogenated heterocycles, including 2-chloropyridines, 2-chloroquinolines, and 2-chloropyrimidines. This compound is valuable in the synthesis of pharmaceuticals and agrochemicals, facilitating the formation of C-C bonds in complex organic molecules. Its utility in diverse chemical transformations makes it an important reagent for organic synthesis and medicinal chemistry research. -
Biochemical Assay Reagent
Octanoate, 99% sodium, primarily acts as a biochemical assay reagent. This compound is utilized in various research applications, including the identification of metabolic pathways and the study of lipid metabolism. Additionally, it exhibits biological activity as an orally active tremor-suppressing agent, making it relevant for investigations in neurology and related fields. -
Biochemical Assay Reagent
NDSB-201 is a biochemical assay reagent characterized by a pyridine group linked to a propane chain, which is further attached to a sulfonate group. This compound serves as a reliable buffer in biochemical and biological research, particularly in electrophoretic applications, due to its ability to maintain a stable pH in aqueous solutions and its low UV absorption properties. Additionally, NDSB-201 is recognized for its capacity to form stable complexes with DNA and other biomolecules, making it a valuable tool for drug delivery and genetic research applications. -
Chromogenic Reagent
p-Dimethylaminobenzaldehyde serves as a chromogenic reagent, primarily targeting the visualization of various chemical species through colorimetric changes. It displays notable utility in the detection and quantification of heavy metal ions, enhancing analytical methodologies in various biochemical research applications. Its ability to form colored complexes makes it a valuable tool in assays and analytical chemistry. -
Biochemical Assay Reagent
Acetylthiocholine iodide serves as a substrate for enzymes such as cholinesterase, enabling the quantification of enzyme activity levels. This compound is utilized in various biochemical assays and has applications in medical research, particularly in neuroscience and organ physiology studies. Its role in enzyme activity determination makes it a valuable reagent for investigating cholinergic signaling pathways. -
SB9 Inhibitor
Serpin B9-IN-1 (BTCA) is a selective inhibitor targeting Serpin B9 (SB9), a natural inhibitor of granzyme B (GrB) that is implicated in promoting lung cancer cell metastasis to the bone marrow. Elevated levels of SB9 in cancer cells enhance their proliferation and metastatic potential through interaction with GrB in an immune cell-dependent manner. Inhibition of SB9 by Serpin B9-IN-1 has been shown to significantly impair immunotherapy responses for lung cancer with bone metastases in the caudal artery (CA) mouse model, making it a valuable reagent for cancer research focused on the tumor microenvironment and immune evasion.
