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Acyl-CoA & Cofactors

Acyl-coenzyme A (acyl-CoA) compounds and enzyme cofactors supply activated substrates and redox carriers for assays. Acyl-CoA thioesters carry acyl groups through fatty acid metabolism and serve as substrates for acyltransferases, dehydrogenases and carboxylases. Crotonyl-CoA is a short-chain unsaturated thioester and the acyl donor for histone lysine crotonylation. Reduced nicotinamide adenine dinucleotide (NADH) and its phosphorylated form NADPH donate electrons to dehydrogenases and reductases. NADPH is offered in several salt forms, including NADPH tetrasodium salt. Sapropterin dihydrochloride is a synthetic form of tetrahydrobiopterin, the cofactor of aromatic amino acid hydroxylases and nitric oxide synthases. Coenzyme FO, a deazaflavin, is the precursor of coenzyme F420 and a light-harvesting chromophore in some DNA photolyases.

Cat. No.

A91266

CAS No.

79171-48-5

(S)-3-Hydroxyoctanoyl-CoA

Synonyms: (S)-3-Hydroxyoctanoyl-Coenzyme A

(S)-3-Hydroxyoctanoyl-CoA is a coenzyme A derivative formed through the condensation of the thiol group of coenzyme A with (S)-3-hydroxyoctanoic acid. This hydroxy fatty acyl-CoA plays a crucial role in lipid metabolism and fatty acid biosynthesis. It is a valuable reagent for research applications focused on metabolic pathways, particularly in studies examining the functions of acyl-CoA derivatives in cellular processes.

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Cat. No.

A91272

CAS No.

4460-95-1

2E-Hexadecenoyl-CoA

Synonyms: 2E-Hexadecenoyl-coenzyme A; trans-2-Hexadecenoyl-CoA; trans-2-Hexadecenoyl-S-coenzyme A

2E-Hexadecenoyl-CoA is a 2-enoyl-CoA derivative and a long-chain fatty acyl-CoA that serves as a key substrate in fatty acid metabolism. It is involved in various biochemical pathways, including fatty acid β-oxidation and lipid synthesis. This compound is essential for studying metabolic processes and investigating the role of fatty acids in cellular functions and energy homeostasis.

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Cat. No.

A91273

CAS No.

100425-71-6

(R)-Phenyllactoyl-CoA

Synonyms: (R)-Phenyllactoyl-coenzyme A

(R)-Phenyllactoyl-CoA is a coenzyme A derivative featuring (R)-phenyllactoyl as the S-acyl group. This compound serves as a critical substrate in studies focused on fatty acid metabolism and acyl-CoA biosynthetic pathways. Its role as an acyl donor in various enzymatic reactions makes it valuable for research applications in metabolic biochemistry and enzymology.

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Cat. No.

A91276

CAS No.

72845-19-3

Citryl-Thioether-CoA

Synonyms: Citryl-Thioether-Coenzyme A

Citryl-Thioether-CoA is a coenzyme A derivative that serves as a substrate for various enzymatic reactions involved in cellular metabolism. This compound exhibits critical biological activity, particularly in the synthesis of thiol esters and in metabolic pathways associated with energy production and biosynthesis. It is particularly applicable in studies of metabolic regulation and enzyme kinetics involving coenzyme A-related processes.

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Cat. No.

A91280

CAS No.

150903-78-9

Tetradec-13-ynoicacid-CoA,thioester

Synonyms: Tetradec-13-ynoic acid - coenzyme A thioester

Tetradec-13-ynoic acid-CoA thioester is a coenzyme A derivative that plays a crucial role in fatty acid metabolism. This compound facilitates the activation of tetradec-13-ynoic acid for subsequent biochemical reactions, making it valuable for research in lipid biochemistry and cellular metabolism. Its applications extend to studying metabolic pathways and the regulation of lipid synthesis.

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Cat. No.

A91281

CAS No.

144253-03-2

N-Methyl-anthraniloyl-CoA

Synonyms: N-Methyl anthraniloyl-coenzyme A

N-Methyl-anthraniloyl-CoA is a coenzyme A derivative that serves as a key bioactive compound in biochemical pathways. It plays a critical role in cellular metabolism and is utilized in studies investigating enzymatic reactions and metabolic regulation. Its unique structure enables researchers to explore its function in various biological processes, making it a valuable reagent for chemical and biochemical research applications.

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Cat. No.

A91295

CAS No.

10478-66-7

2-Hydroxybenzoyl-CoA

Synonyms: o-Hydroxybenzoyl-coenzyme A

2-Hydroxybenzoyl-CoA is a coenzyme A derivative that plays a crucial role in various biochemical pathways. It serves as an important substrate in the metabolism of aromatic compounds and is involved in the synthesis and degradation of key metabolites. This compound is pertinent for studies in enzymology and metabolic engineering, facilitating research on aromatic compound metabolism and regulatory mechanisms within cellular systems.

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Cat. No.

A91297

CAS No.

898249-68-8

12,13-Didehydroacyl-CoA

Synonyms: 12,13-Didehydroacyl-coenzyme A

12,13-Didehydroacyl-CoA is a coenzyme A derivative that plays a crucial role in fatty acid metabolism. This compound serves as an intermediate in various biochemical pathways, imparting significance in studies related to lipid metabolism and energy production. Its unique structural properties make it a valuable reagent for exploring enzymatic activities and metabolic regulation in research applications.

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Cat. No.

A91309

CAS No.

103319-60-4

Benzoyl-acetyl-CoA

Synonyms: Benzoyl acetyl-coenzyme A

Benzoyl-acetyl-CoA is a coenzyme A derivative that plays a critical role in acyl group transfer reactions. This compound is involved in various metabolic pathways, particularly in the biosynthesis of aromatic compounds and fatty acid metabolism. It is valuable for research applications focusing on enzyme kinetics and metabolic regulation studies.

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Cat. No.

A91310

CAS No.

6008-96-4

3-Oxoadipyl-CoA

Synonyms: Coenzyme A; 3-oxohexanedioate

3-Oxoadipyl-CoA is a coenzyme A derivative that serves as a crucial metabolite in fatty acid synthesis and degradation pathways. This compound plays a significant role in the regulation of energy metabolism and is instrumental in enzymatic reactions involving acyl transfer. 3-Oxoadipyl-CoA is valuable for research applications focused on metabolic disorders, lipid metabolism, and the biochemical pathways involving coenzyme A derivatives.

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Cat. No.

A91313

CAS No.

134998-45-1

8,9-EET-CoA

Synonyms: 8,9-Epoxy-(5Z,11Z,14Z)-eicosatrienoyl-coenzyme A

8,9-EET-CoA is a coenzyme A derivative that plays a critical role in lipid metabolism. As a key intermediate in the biosynthesis of bioactive lipids, 8,9-EET-CoA is involved in the modulation of various physiological processes, including inflammation and angiogenesis. This compound is valuable for research applications focused on the metabolic pathways of eicosanoids and the functional roles of lipid mediators in cellular signaling.

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Cat. No.

A91314

CAS No.

148471-95-8

6-Hydroxycyclohex-1-ene-1-carboxyl-CoA

Synonyms: 6-Hydroxycyclohex-1-enecarbonyl-coenzyme A

6-Hydroxycyclohex-1-ene-1-carboxyl-CoA is a coenzyme A derivative that plays a critical role in metabolic pathways. It serves as an important substrate in the synthesis and metabolism of various organic compounds. This reagent is particularly useful in studies related to enzymatic activity and metabolic flux analysis, facilitating research in biochemistry and cellular biology.

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Cat. No.

A91315

CAS No.

84061-72-3

3,4-Pentadienoyl-CoA

Synonyms: 3,4-Pentadienoyl-Coenzyme A

3,4-Pentadienoyl-CoA is a coenzyme A derivative that serves as a crucial intermediate in various metabolic pathways. It plays a significant role in fatty acid metabolism and lipid biosynthesis. This compound is valuable for research applications focused on understanding the enzymatic processes and regulatory mechanisms involving CoA derivatives in cellular metabolism.

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Cat. No.

A91323

CAS No.

1245945-82-7

cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA

Synonyms: cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-coenzyme A

Cis-2-Methyl-5-isopropylhexa-2,5-dienoyl-CoA is a coenzyme A derivative that participates in various biochemical pathways involving fatty acid metabolism and synthesis. Its structure allows it to function as an important substrate for enzymatic reactions, particularly those related to lipid biosynthesis and degradation. This reagent is useful for research applications focused on metabolic regulation, enzyme kinetics, and the role of CoA esters in cellular metabolism.

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Cat. No.

A91326

CAS No.

3902-16-7

Citramalyl-CoA

Synonyms: Citramalyl-coenzyme A

Citramalyl-CoA is a coenzyme A derivative that plays a crucial role in metabolic pathways. It is involved in the biosynthesis of essential metabolites and acts as an intermediate in the citramalate pathway. This compound is utilized in research applications related to metabolism, cellular energy production, and enzymatic activity studies. Its role in synthesizing key biochemical intermediates makes it valuable for exploring the biochemical processes underlying various physiological functions.

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Cat. No.

A91332

CAS No.

177468-82-5

trans,trans-Octa-2,4-dienoyl-CoA

Synonyms: trans; trans-Octa-2,4-dienoyl-coenzyme A

trans,trans-Octa-2,4-dienoyl-CoA is a coenzyme A derivative that plays a critical role in fatty acid metabolism. This compound serves as an intermediate in the catabolism of unsaturated fatty acids, facilitating the breakdown and conversion of fatty acids into energy. It is of particular interest in research related to metabolic diseases and lipid biosynthesis pathways.

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Cat. No.

A91341

CAS No.

123052-13-1

3-(Methylthio)propanoyl-CoA

Synonyms: 3-(Methylthio)propanoyl-coenzyme A

3-(Methylthio)propanoyl-CoA is a coenzyme A derivative that serves as an acyl-CoA. This compound plays a crucial role in metabolic pathways involving the transfer of acyl groups, contributing to the synthesis and degradation of fatty acids. Its application in biochemical research includes studying lipid metabolism and cellular energy production.

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Cat. No.

A91343

CAS No.

169337-39-7

3,5,8,11,14-Eicosapentenoyl-CoA

Synonyms: 3,5,8,11,14-Eicosapentenoyl-coenzyme A

3,5,8,11,14-Eicosapentenoyl-CoA is a coenzyme A derivative that plays a crucial role in fatty acid metabolism. This compound acts as an acyl donor in various biochemical pathways, facilitating the synthesis and degradation of fatty acids. It is primarily used in research related to lipid metabolism, energy production, and cellular signaling processes.

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Cat. No.

A91361

CAS No.

144319-98-2

3-Indoleacryloyl-CoA

Synonyms: 3-Indoleacryloyl-coenzyme A

3-Indoleacryloyl-CoA is a coenzyme A derivative that functions as an important biochemical tool in metabolic research. This compound participates in various enzymatic reactions, contributing to the study of biochemical pathways involving indole derivatives. Its biological activity is essential for exploring the metabolic effects of indole acylation in cellular processes, making it valuable for researchers investigating metabolic disorders and signaling pathways.

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Cat. No.

A91363

CAS No.

603954-78-5

(9Z,12Z)-Hexadeca-9,12,15-trienoyl-CoA

Synonyms: (9Z,12Z)-Hexadeca-9,12,15-trienoyl-coenzyme A

(9Z,12Z)-Hexadeca-9,12,15-trienoyl-CoA is a coenzyme A derivative characterized by its unsaturated fatty acyl structure. It serves as a crucial intermediate in fatty acid metabolism, participating in various cellular processes, including lipid synthesis and degradation. This compound is relevant for research applications involving metabolic pathways and mitochondrial function, offering insights into fatty acid oxidation and energy production in biological systems.

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Cat. No.

A91376

CAS No.

404355-20-0

3-Fluorobenzoyl-CoA

Synonyms: 3-Fluorobenzoyl-coenzyme A

3-Fluorobenzoyl-CoA is a coenzyme A derivative that acts as a key intermediate in metabolic pathways involving aromatic compounds. Its primary mechanism involves the incorporation of the 3-fluorobenzoyl group into various enzymatic reactions. This compound is valuable for studying the metabolism of fluorinated aromatic compounds and can be utilized in research applications related to drug metabolism and synthetic biology.

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Cat. No.

A91384

CAS No.

852101-47-4

cis-Vaccenoyl-CoA

Synonyms: cis-Vaccenyl-coenzyme A

Cis-Vaccenoyl-CoA is a coenzyme A derivative that serves as an important intermediate in fatty acid metabolism. This compound plays a crucial role in the synthesis and degradation of unsaturated fatty acids, which are essential for various cellular processes. Its biological activity makes it valuable for research applications in lipid metabolism, enzymatic studies, and metabolic engineering.

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Cat. No.

A91395

CAS No.

79955-48-9

Carboxymethyl-CoA

Synonyms: Carboxymethyl-coenzyme A

Carboxymethyl-CoA is a coenzyme A derivative that acts as an important biochemical intermediate. It plays a crucial role in various metabolic pathways, including fatty acid metabolism and the biosynthesis of secondary metabolites. This compound is utilized in research studies focused on enzymatic reactions, metabolic engineering, and the investigation of lipid metabolism processes.

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Cat. No.

A91399

CAS No.

211363-15-4

(24R,25R)-3Alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA

Synonyms: (24R,25R)-3Alpha; 7alpha; 24-trihydroxy-5beta-cholestan-26-oyl-coenzyme A

(24R,25R)-3Alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA is a steroidal acyl-CoA derivative known for its role as a coenzyme A analogue. This compound is involved in fatty acid metabolism and the synthesis of bioactive lipids, making it a valuable tool in biochemical research. Its applications include studies on cholesterol metabolism and the regulation of lipid biosynthesis pathways.

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Cat. No.

A91405

CAS No.

123406-77-9

2-Tetradecenoyl-CoA

Synonyms: Coenzyme A; S-2-tetradecenoate; Tetradec-2-trans-enoyl-CoA; trans-2-Tetradecenoylcoenzyme A

2-Tetradecenoyl-CoA is a coenzyme A derivative that plays a critical role in various metabolic pathways. This compound is involved in fatty acid metabolism and lipid biosynthesis, serving as a substrate for enzymes that utilize acyl-CoA in metabolic reactions. It is useful in studies related to lipid biochemistry and cellular metabolism, providing insights into fatty acid activation and transport mechanisms.

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