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Acyl-coenzyme A (acyl-CoA) compounds and enzyme cofactors supply activated substrates and redox carriers for assays. Acyl-CoA thioesters carry acyl groups through fatty acid metabolism and serve as substrates for acyltransferases, dehydrogenases and carboxylases. Crotonyl-CoA is a short-chain unsaturated thioester and the acyl donor for histone lysine crotonylation. Reduced nicotinamide adenine dinucleotide (NADH) and its phosphorylated form NADPH donate electrons to dehydrogenases and reductases. NADPH is offered in several salt forms, including NADPH tetrasodium salt. Sapropterin dihydrochloride is a synthetic form of tetrahydrobiopterin, the cofactor of aromatic amino acid hydroxylases and nitric oxide synthases. Coenzyme FO, a deazaflavin, is the precursor of coenzyme F420 and a light-harvesting chromophore in some DNA photolyases.
Synonyms: L-Proline-coenzyme A
L-Proline-CoA is a coenzyme A derivative that functions as an important metabolic intermediate. It plays a crucial role in the metabolism of proline and is involved in various biochemical pathways. This compound is used in research to investigate metabolic processes, enzymatic reactions, and the regulation of amino acid metabolism.
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Synonyms: 7-Methyloctanoyl-coenzyme A
7-Methyloctanoyl-CoA is a coenzyme A derivative that plays a vital role in fatty acid metabolism. It serves as an acyl donor in various biochemical reactions, facilitating the attachment of fatty acids to proteins and substrates. This compound is essential for studies related to lipid metabolism, enzyme kinetics, and metabolic engineering. Researchers utilize 7-Methyloctanoyl-CoA to explore its implications in energy production and cellular signaling pathways.
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Oleoyl Coenzyme A triammonium is the ammonium salt of Oleoyl Coenzyme A, primarily functioning as a substrate in metabolic processes. It exhibits inhibitory effects on neutral lipase, which is significant in lipid metabolism. This compound is essential for studying ATP-dependent signal transduction pathways in plants and can be employed in various biological research applications related to fatty acid metabolism and regulation.
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trans-2-Decenoylcoenzyme A is a coenzyme A derivative involved in lipid metabolism. This compound functions as a substrate for various acyl-CoA synthetases and is essential for the biosynthesis of unsaturated fatty acids. It is utilized in biochemical research to study fatty acid oxidation and metabolic pathways related to lipid biosynthesis.
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Synonyms: Coenzyme A,S-1,5-cyclohexadiene-1-carboxylate
1,5-Dienoyl-CoA is a coenzyme A derivative that serves as a crucial intermediate in fatty acid metabolism. This compound is involved in the conjugation and activation of fatty acids, facilitating their entry into metabolic pathways. Research applications include studying lipid biosynthesis and the regulation of energy metabolism in various biological systems.
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Synonyms: (24R,25R)-3Alpha; 7alpha; 12alpha; 24-Tetrahydroxy-5beta-cholestanoyl-coenzyme A
(24R,25R)-3Alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestan-26-oyl-CoA is a coenzyme A derivative characterized by its unique acyl structure. This compound plays a crucial role in facilitating metabolic processes and lipid biosynthesis. Its biological activity is relevant for research applications focusing on cholesterol metabolism and related pathways.
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Synonyms: Cerotoyl Coenzyme A
Cerotoyl-CoA is a coenzyme A derivative that plays a crucial role in lipid metabolism and fatty acid biosynthesis. It is involved in acyl group transfer reactions, facilitating the transport and activation of cerotic acid within cellular pathways. This compound is valuable for research applications in metabolic studies and understanding fatty acid synthesis and regulation.
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Synonyms: Desulfocoenzyme A
Dethia-CoA, a coenzyme A derivative, functions as a pivotal metabolic intermediate involved in various biochemical pathways. This compound plays a significant role in the regulation of acyl-CoA-dependent processes and is utilized extensively in research focusing on fatty acid metabolism and biochemical studies of energy metabolism. Dethia-CoA is particularly valuable for investigations pertaining to enzyme kinetics and the study of CoA-related metabolic functions.
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Synonyms: (3S)-Citramalyl-coenzyme A
(3S)-Citramalyl-CoA is a coenzyme A derivative that exhibits critical involvement in metabolic pathways. It serves as a substrate in the biosynthesis of various important compounds, facilitating enzymatic reactions that contribute to cellular metabolism. This compound is valuable for research applications focused on enzymology, metabolic regulation, and biochemistry studies related to coenzyme A-dependent processes.
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Synonyms: 3-Oxoicosanoyl-coenzyme A
3-Oxoicosanoyl-CoA is a coenzyme A derivative that plays a critical role in fatty acid metabolism. This compound serves as an important acyl donor in biochemical pathways, facilitating the synthesis and degradation of fatty acids. Its application in research includes studying lipid metabolism and understanding fatty acid-mediated signaling processes, making it a valuable tool for investigating cellular energy homeostasis and related disorders.
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Synonyms: 7-Oxodecanoyl-coenzyme A
7-Oxodecanoyl-CoA is a coenzyme A derivative that plays a crucial role in metabolic pathways involving fatty acid metabolism. Its primary mechanism involves facilitating acyl group transfer, making it essential for the synthesis and degradation of fatty acids. This compound is beneficial for research applications studying lipid metabolism, enzymatic activity, and metabolic disease modeling.
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Synonyms: 18-Hydroxyoleoyl-coenzyme A
18-Hydroxyoleoyl-CoA is a coenzyme A derivative with an omega-hydroxy fatty acyl structure. It plays a significant role in lipid metabolism and fatty acid synthesis, serving as an important intermediate in various biochemical pathways. Research applications include studying lipid metabolism, fatty acid signaling, and the regulatory mechanisms of energy homeostasis.
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(9Z-Octadecenyl)-CoA triammonium is a long-chain acyl-CoA ester, serving as a vital coenzyme in various biochemical pathways. It plays a crucial role in the regulation of fatty acid synthesis and is involved in enzyme systems, vesicle trafficking, as well as the function of ion channels and ion pumps. This compound is essential for studying metabolic processes and lipid metabolism in cellular and molecular research.
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Synonyms: 06:0 Coenzyme A triammonium
Hexanoyl-Coenzyme A triammonium is a medium-chain fatty acyl CoA that serves as an acyl donor substrate for the enzyme ghrelin O-acyltransferase (GOAT). Its primary mechanism involves the acylation of ghrelin, which plays a critical role in regulating energy homeostasis and appetite. This compound is valuable in metabolic research and studies examining the role of ghrelin acylation in physiological processes and disorders related to energy balance.
Synonyms: O-Succinylbenzoyl-coenzyme A
O-Succinylbenzoyl-CoA is a coenzyme A derivative that acts as an important intermediate in various biochemical processes. This compound is utilized in metabolic studies, specifically in the investigation of enzymes involved in fatty acid metabolism and acyl-CoA conjugation. Its unique structure allows for exploration of biochemical pathways and regulation related to CoA-dependent reactions.
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Synonyms: 3-Ketopimelyl-coenzyme A
3-Ketopimelyl-CoA is a coenzyme A derivative that plays a crucial role in metabolic pathways involving fatty acid synthesis and degradation. Its unique structure enables participation in biochemical reactions that regulate mitochondrial functions and energy metabolism. This compound is valuable for research applications in studying metabolic disorders and evaluating enzyme activity linked to CoA-dependent processes.
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2'-(5''-Phosphoribosyl)-3'-dephospho-CoA is a coenzyme A derivative featuring a 5''-phospho-D-ribosyl substituent at C-2' and a dephosphorylated structure at C-3'. This compound plays a key role in cellular metabolism, particularly in enzymatic processes involving coenzyme A. It serves as a valuable tool in biochemical research, especially in studies related to enzymatic reactions, metabolic pathways, and the biochemical roles of coenzyme A structures.
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Synonyms: Heptadecanonyldethio-coenzyme A
Heptadecanonyldethio-CoA is a coenzyme A derivative that plays a critical role in lipid metabolism and fatty acid synthesis. This compound participates in the acylation of various substrates, facilitating enzymatic reactions involved in cellular energy production and metabolic regulation. It is useful for studies focused on metabolic pathways, enzymatic function, and the biochemical roles of lipid-derived metabolites.
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Synonyms: Coenzyme A,S-ethane(dithioate)
Acetyldithio-CoA is a coenzyme A derivative that plays a crucial role in biochemical reactions involving fatty acid metabolism and thiol-based redox regulation. Its primary mechanism is to facilitate the transfer of acetyl groups in metabolic pathways. This compound is utilized in research applications that explore metabolic processes, enzyme activity, and the function of coenzymes in cellular systems.
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Synonyms: L-Isoleucine-coenzyme A
L-Isoleucine-CoA is a coenzyme A derivative that functions as a key metabolite in amino acid metabolism. It serves as a substrate for various enzymes involved in energy production and protein synthesis pathways. This compound is valuable for research focused on metabolic regulation, enzymatic activity, and the interplay between amino acids and CoA in cellular processes.
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Synonyms: Coenzyme A,S-(9Z)-9-tetradecenoate
Myristoleoyl-CoA is a coenzyme A derivative that serves as a critical substrate in lipid metabolism. This compound is involved in the biosynthesis of fatty acids and can influence metabolic pathways related to energy production and cellular signaling. Myristoleoyl-CoA is valuable for research applications focusing on lipid biochemistry, metabolic disorders, and enzymatic reactions related to fatty acid synthesis.
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Synonyms: 4,8-Dimethylnonanoyl-Coenzyme A; Dimethylnonanoyl-CoA; Dimethylnonanoyl-coenzyme A
4,8-Dimethylnonanoyl-CoA is a coenzyme A derivative that plays a critical role in fatty acid metabolism. It serves as an acyl donor in various biochemical pathways, facilitating the transport and activation of fatty acids for subsequent oxidation or biosynthesis. This compound is valuable for research applications focusing on metabolic studies and lipid biology.
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Synonyms: trans-7-Methyloct-2-enoyl-coenzyme A
Trans-7-Methyloct-2-enoyl-CoA is a coenzyme A derivative that serves as an important biochemical intermediate in fatty acid metabolism. It plays a crucial role in various enzymatic reactions, particularly in the biosynthesis of lipid compounds and energy production pathways. This compound is utilized in research applications focusing on metabolic processes and the regulation of fatty acid biosynthesis.
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(3,4-Dihydroxyphenyl)propionyl-CoA is a Coenzyme A derivative that plays a crucial role in metabolic processes. This compound is involved in the acylation of aromatic amino acids and is significant for studying pathways related to neurotransmitter metabolism. Its biological activity makes it relevant for research in neurobiology, metabolism, and the functioning of coenzyme A in synthesizing various biomolecules.
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Synonyms: β-Hydroxyisovaleryl coenzyme A
3-Hydroxyisovaleryl-CoA is a coenzyme A derivative that plays a critical role in various metabolic pathways. It participates in the catabolism of branched-chain amino acids and fatty acids, making it significant for studies related to energy metabolism and mitochondrial function. This compound is useful in biochemical assays and research on metabolic disorders involving impaired fatty acid oxidation.
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