Acyl-CoA & Cofactors

Acyl-coenzyme A (acyl-CoA) compounds and enzyme cofactors supply activated substrates and redox carriers for assays. Acyl-CoA thioesters carry acyl groups through fatty acid metabolism and serve as substrates for acyltransferases, dehydrogenases and carboxylases. Crotonyl-CoA is a short-chain unsaturated thioester and the acyl donor for histone lysine crotonylation. Reduced nicotinamide adenine dinucleotide (NADH) and its phosphorylated form NADPH donate electrons to dehydrogenases and reductases. NADPH is offered in several salt forms, including NADPH tetrasodium salt. Sapropterin dihydrochloride is a synthetic form of tetrahydrobiopterin, the cofactor of aromatic amino acid hydroxylases and nitric oxide synthases. Coenzyme FO, a deazaflavin, is the precursor of coenzyme F420 and a light-harvesting chromophore in some DNA photolyases.

Items 226-250 of 520

  • D-3-Hydroxybutyryl-CoA
    Cat. No.
    A90826

    D-3-Hydroxybutyryl-CoA

    Synonyms: D-β-Hydroxybutyryl-CoA

    D-3-Hydroxybutyryl-CoA is a coenzyme A derivative that plays a key role in metabolic pathways. It is involved in the synthesis and degradation of fatty acids and serves as an important substrate for enzymatic reactions. This compound is significant in research applications focused on energy metabolism, lipid biosynthesis, and the study of metabolic disorders.

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  • Gabaculine-CoA
    Cat. No.
    A90836

    Gabaculine-CoA

    Synonyms: Gabaculine-coenzyme A

    Gabaculine-CoA is a derivative of coenzyme A that serves as a crucial intermediary in biochemical pathways. This compound plays a significant role in the synthesis and metabolism of neurotransmitters. It is commonly utilized in research focused on neurochemical processes and the modulation of neurotransmitter systems.

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  • Phenoxyacetyl-CoA
    Cat. No.
    A90861

    Phenoxyacetyl-CoA

    Synonyms: Phenoxyacetyl-coenzyme A

    Phenoxyacetyl-CoA is a coenzyme A derivative that plays a critical role in various biochemical processes. This compound serves as an acyl donor in enzymatic reactions, facilitating the transfer of phenoxyacetyl groups. It is valuable for research in metabolic pathways, particularly in studies involving fatty acid metabolism and acylation reactions. Additionally, Phenoxyacetyl-CoA can be utilized in drug development and the synthesis of biologically active compounds.

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  • 20-Methyl-3-oxopregna-4,17-dien-21-oyl-CoA
    Cat. No.
    A90871

    20-Methyl-3-oxopregna-4,17-dien-21-oyl-CoA

    Synonyms: 20-Methyl-3-oxopregna-4,17-dien-21-oyl-coenzyme A

    20-Methyl-3-oxopregna-4,17-dien-21-oyl-CoA is a steroidal acyl-CoA derivative that acts as an active form of a coenzyme A. This compound is involved in various metabolic processes, particularly in the synthesis and metabolism of steroids. Its biological activity makes it useful for research in steroid biochemistry and metabolism studies.

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  • S-(3-Oxobutyl)-CoA
    Cat. No.
    A90874

    S-(3-Oxobutyl)-CoA

    Synonyms: Coenzyme A,S-(3-oxobutyl)-; S-(3-Oxobutyl)coenzyme A

    S-(3-Oxobutyl)-CoA is a coenzyme A derivative that acts as a crucial metabolic intermediate. It participates in various biochemical pathways, including fatty acid metabolism and energy production. This compound is valuable for research applications involving enzyme assays and investigating acyl-CoA thioester metabolism.

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  • 1,4-Dihydroxy-2-naphthoyl-CoA
    Cat. No.
    A90878

    1,4-Dihydroxy-2-naphthoyl-CoA

    Synonyms: 1,4-Dihydroxy-2-naphthoyl-coenzyme A

    1,4-Dihydroxy-2-naphthoyl-CoA is a Coenzyme A derivative formed through the condensation of coenzyme A's thiol group with 1,4-dihydroxy-2-naphthoic acid. This acyl-CoA compound is integral in various biochemical pathways, particularly in the metabolism of aromatic compounds. 1,4-Dihydroxy-2-naphthoyl-CoA is employed in research applications focusing on enzymatic activity and metabolic regulation, offering insights into cellular metabolism and potential therapeutic targets.

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  • Palmitoleoyl-CoA lithium
    Cat. No.
    A90879

    Palmitoleoyl-CoA lithium

    Palmitoleoyl-CoA lithium is the lithium salt derivative of Palmitoleoyl-CoA, serving as a biochemical assay reagent. This compound facilitates the activation and mitochondrial transport of fatty acids for β-oxidation. It plays a significant role in inducing mitochondrial dysfunction by promoting cardiac mitochondrial membrane permeability transition. Additionally, Palmitoleoyl-CoA lithium regulates metabolic pathways through allosteric modulation of AMPK β1-isoforms, making it a valuable tool in metabolic research.

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  • Stearoyl-epsilon-CoA
    Cat. No.
    A90889

    Stearoyl-epsilon-CoA

    Synonyms: Stearoyl-(1,N(6))-etheno-coenzyme A

    Stearoyl-epsilon-CoA is a coenzyme A derivative known for its role in fatty acid metabolism. It serves as an important intermediate in the biosynthesis of complex lipids, facilitating various metabolic pathways related to lipid biosynthesis and energy production. This compound is valuable in research applications involving lipid metabolism and related enzymatic processes.

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  • Maleyl-CoA
    Cat. No.
    A90894

    Maleyl-CoA

    Synonyms: Maleyl-coenzyme A; S-[(Z)-Hydrogen 2-butenedioate]-CoA; Coenzyme A,S-[(Z)-Hydrogen 2-butenedioate]

    Maleyl-CoA is a coenzyme A derivative that serves as an important intermediate in various metabolic pathways. It plays a critical role in the metabolism of unsaturated fatty acids and certain amino acids. Maleyl-CoA is utilized in research applications focusing on metabolic disorders, enzymatic activity, and the regulation of energy metabolism.

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  • (S)-3-Hydroxypalmitoyl-CoA
    Cat. No.
    A90897

    (S)-3-Hydroxypalmitoyl-CoA

    Synonyms: (S)-3-Hydroxypalmitoyl-coenzyme A

    (S)-3-Hydroxypalmitoyl-CoA is a coenzyme A derivative designed for research in lipid metabolism. This long-chain (3S)-hydroxy fatty acyl-CoA plays a crucial role in fatty acid synthesis and metabolism, serving as an essential substrate for enzymatic reactions. Its biological activity makes it valuable for studies related to energy metabolism, cell signaling, and the regulation of metabolic pathways.

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  • Delta(4)-dafachronoyl-CoA
    Cat. No.
    A90905

    Delta(4)-dafachronoyl-CoA

    Synonyms: Delta(4)-dafachronoyl-coenzyme A

    Delta(4)-dafachronoyl-CoA is a coenzyme A derivative that plays a crucial role in lipid metabolism. This compound is involved in the fatty acid synthesis and degradation pathways, serving as an essential intermediate in the acylation processes. Its utility in biochemical research facilitates the study of metabolic regulation and the characterization of fatty acid derivatives in various biological contexts.

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  • Phenylglyoxylyl-CoA
    Cat. No.
    A90908

    Phenylglyoxylyl-CoA

    Synonyms: Phenylglyoxylyl-coenzyme A

    Phenylglyoxylyl-CoA is a coenzyme A derivative that functions as an important metabolic intermediate in various biochemical pathways. It plays a critical role in the biosynthesis and degradation of phenolic compounds, facilitating their conversion and utilization in cellular metabolism. Research applications include studies on enzyme kinetics and metabolic flux analysis, providing insight into phenylalanine metabolism and its related disorders.

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  • Butylmalonyl-CoA
    Cat. No.
    A90912

    Butylmalonyl-CoA

    Synonyms: Butylmalonyl-coenzyme A

    Butylmalonyl-CoA is a coenzyme A derivative that serves as a key intermediate in various biochemical pathways. This compound is primarily utilized in studies focusing on fatty acid metabolism and enzyme regulation. Its application in metabolic engineering and biochemistry research enhances the understanding of cellular processes involving acyl-CoA substrates.

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  • 3-Oxo-4-methyl-pentanoyl-CoA
    Cat. No.
    A90913

    3-Oxo-4-methyl-pentanoyl-CoA

    Synonyms: 3-Oxo-4-methyl-pentanoyl-coenzyme A

    3-Oxo-4-methyl-pentanoyl-CoA is a coenzyme A derivative that plays a critical role in metabolic pathways. This compound is involved in the regulation of fatty acid metabolism and is essential for the biosynthesis of various metabolites. It is utilized in research applications focused on understanding metabolic disorders and enzymatic functions related to coenzyme A derivatives.

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  • (R,S)-(Hydroxy(phenyl)methyl)succinyl-CoA
    Cat. No.
    A90916

    (R,S)-(Hydroxy(phenyl)methyl)succinyl-CoA

    Synonyms: (2S)-2-((R)-Hydroxybenzyl)succinyl-coenzyme A

    (R,S)-(Hydroxy(phenyl)methyl)succinyl-CoA is a coenzyme A derivative that serves as an important molecular probe in biochemical research. This compound is involved in the study of enzymatic reactions that utilize coenzyme A and contributes to the understanding of metabolic pathways. Its unique structure enables exploration of its role in various biological processes, making it valuable for investigations into cellular metabolism and biochemical assays.

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  • trans-2-Icosenoyl-CoA
    Cat. No.
    A90917

    trans-2-Icosenoyl-CoA

    Synonyms: 2-trans-Eicosenoyl-CoA; trans-2-Icosenoyl-coenzyme A

    trans-2-Icosenoyl-CoA is a coenzyme A derivative that plays a crucial role in lipid metabolism. This molecule is involved in the synthesis and degradation of fatty acids, making it significant for studies related to energy metabolism and lipid biosynthesis. It serves as an important biochemical tool for researchers investigating the pathways of fatty acid elongation and oxidation in various biological contexts.

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  • 2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA
    Cat. No.
    A90924

    2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA

    Synonyms: 2-Hydroxy-6-oxocyclohexane-1-carbonyl-coenzyme A

    2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA is a Coenzyme A derivative that plays a crucial role in metabolic processes. This compound functions as a 3-oxoacyl-CoA, participating in fatty acid metabolism and energy production pathways. It is useful for research applications related to metabolic regulation and enzyme activity involving CoA-dependent reactions.

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  • 2-Hydroxytetradecanoyl-CoA
    Cat. No.
    A90967

    2-Hydroxytetradecanoyl-CoA

    Synonyms: 2-Hydroxytetradecanoyl-coenzyme A

    2-Hydroxytetradecanoyl-CoA is a hydroxy fatty-acyl derivative of coenzyme A. It serves as an important substrate in metabolic pathways involving lipid metabolism and fatty acid synthesis. This compound is utilized in biochemical research to study acyl-CoA metabolism and its implications in various physiological and pathological processes, including cell signaling and energy homeostasis.

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  • 3-Aminobutanoyl-CoA
    Cat. No.
    A90974

    3-Aminobutanoyl-CoA

    Synonyms: 3-Aminobutanoyl-coenzyme A

    3-Aminobutanoyl-CoA is a coenzyme A derivative that plays a crucial role in amino acid metabolism and energy production. This compound acts as a substrate for various enzymatic reactions, facilitating the synthesis and degradation of amino acids. Its biological activity is significant in research applications focusing on metabolic pathways, enzyme regulation, and cellular energy dynamics.

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  • (2R)-Methylmalonyl-CoA
    Cat. No.
    A90985

    (2R)-Methylmalonyl-CoA

    Synonyms: (2R)-Methylmalonyl-coenzyme A

    (2R)-Methylmalonyl-CoA is a coenzyme A derivative involved in metabolic pathways that facilitate the catabolism of certain amino acids and odd-chain fatty acids. It serves as a key intermediate in the methylmalonyl-CoA pathway, crucial for the synthesis of succinyl-CoA. This reagent is valuable for research applications in metabolic disorders and enzymatic activity studies related to CoA-dependent processes.

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  • trans-2-Hexacosenoyl-CoA
    Cat. No.
    A90993

    trans-2-Hexacosenoyl-CoA

    Synonyms: trans-2-Hexacosenoyl-coenzyme A

    trans-2-Hexacosenoyl-CoA is a coenzyme A derivative that plays a crucial role in fatty acid metabolism. It is involved in the synthesis and degradation of long-chain fatty acids, making it significant in lipid biosynthesis and energy production. This compound can be utilized in research related to metabolic pathways, lipid metabolism, and energy homeostasis.

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  • 3-(Methylthio)acryloyl-CoA
    Cat. No.
    A90997

    3-(Methylthio)acryloyl-CoA

    Synonyms: 3-(Methylthio)acryloyl-coenzyme A

    3-(Methylthio)acryloyl-CoA is a coenzyme A derivative functioning as an acyl-CoA thioester. This compound plays a pivotal role in biochemical pathways involving lipid metabolism and energy production. It is utilized in research applications related to thioester reactivity and metabolic regulation, contributing to the understanding of various cellular processes.

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  • 3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA
    Cat. No.
    A91001

    3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA

    Synonyms: 3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-coenzyme A

    3-Hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA is a derivative of coenzyme A, functioning as a crucial intermediate in metabolic pathways. It is involved in the acylation of various substrates, contributing to fatty acid metabolism and energy production. This compound can be utilized in studies focused on metabolic disorders and enzymatic activity of acyl-CoA synthetases and acyltransferases.

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  • 3-Methyldodecanoyl-CoA
    Cat. No.
    A91055

    3-Methyldodecanoyl-CoA

    Synonyms: 3-Methyldodecanoyl-coenzyme A

    3-Methyldodecanoyl-CoA is a coenzyme A derivative that plays a crucial role in fatty acid metabolism. It serves as an acyl-CoA compound involved in various enzymatic reactions, including fatty acid elongation and oxidation. This reagent is valuable in biochemical research focused on lipid metabolism and acyl-CoA biosynthesis pathways. Its use can provide insights into metabolic processes and potential therapeutic targets in metabolic disorders.

    Out of stock

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  • Fenbufen-CoA
    Cat. No.
    A91060

    Fenbufen-CoA

    Synonyms: Fenbufen-coenzyme A

    Fenbufen-CoA is a coenzyme A derivative that serves as a crucial metabolic intermediate. It is involved in the biochemical pathways of phenylbutyrate metabolism, demonstrating anti-inflammatory properties. This reagent is essential for research applications related to lipid metabolism and the investigation of metabolic disorders, making it valuable in the study of pharmacokinetics and drug metabolism.

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Items 226-250 of 520

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