Acyl-CoA & Cofactors

Cat. No.

A92953

CAS No.

2348494-06-2

L-Threonine-CoA

Synonyms: L-Threonine-coenzyme A

L-Threonine-CoA is a derivative of coenzyme A, acting primarily as a substrate for various enzymatic reactions involving threonine metabolism. It plays a critical role in the biosynthesis of essential metabolites and in the modulation of cellular energy pathways. This compound is useful for research applications focusing on amino acid metabolism, as well as in studies investigating the role of coenzyme A derivatives in cellular processes.

Cat. No.

A92954

CAS No.

149474-96-4

alpha-Methylcaproyl-CoA

Synonyms: alpha-Methylcaproyl-coenzyme A

alpha-Methylcaproyl-CoA is a coenzyme A derivative that serves as a crucial intermediary in various metabolic pathways. It is primarily involved in the biosynthesis of fatty acids and the metabolism of branched-chain amino acids. Research applications include studies on lipid metabolism and the regulation of energy homeostasis.

Cat. No.

A92973

CAS No.

130274-25-8

2-Fluoromyristoyl-CoA

Synonyms: 2-Fluoromyristoyl coenzyme A

2-Fluoromyristoyl-CoA is a coenzyme A derivative that functions primarily as a lipid metabolic intermediate. It plays a critical role in fatty acid metabolism, enabling the study of fatty acid synthesis and elongation pathways. This compound is widely utilized in biochemical research to explore lipid-related diseases and metabolic disorders.

Cat. No.

A92990

CAS No.

60731-52-4

Chenodeoxycholyl-CoA

Synonyms: Chenodeoxycholoyl-coenzyme A

Chenodeoxycholyl-CoA is a coenzyme A derivative that plays a crucial role in bile acid metabolism. This compound participates in the synthesis and conjugation of bile acids, influencing lipid digestion and absorption. Its biological activity makes Chenodeoxycholyl-CoA valuable for research in metabolic disorders, enzymatic pathways, and cholestasis-related studies.

Cat. No.

A92991

CAS No.

917-43-1

(S)-3-Hydroxylauroyl-CoA

Synonyms: (S)-3-Hydroxylauroyl-coenzyme A

(S)-3-Hydroxylauroyl-CoA is a hydroxy fatty acyl-CoA derivative that acts as a key substrate for various metabolic processes. It is formed through the condensation of the thiol group of coenzyme A with the carboxylic acid group of (S)-3-hydroxydodecanoic acid. This compound is essential for studying lipid metabolism and investigating the role of acyl-CoA derivatives in cellular functions and signaling pathways.

Cat. No.

A92995

CAS No.

66442-95-3

Dethiaacetyl-CoA

Synonyms: Acetonyldethio-coenzyme A

Dethiaacetyl-CoA is a coenzyme A derivative with a unique structural modification that replaces the sulfur atom in coenzyme A with a carbon atom. This compound is primarily used in biochemical research to explore fatty acid metabolism and the modulation of acetylation pathways. Dethiaacetyl-CoA can serve as a substrate or cofactor in enzymatic reactions, providing insights into the function and regulation of various metabolic processes. Its utility in studies related to cellular energy production and lipid biosynthesis makes it a valuable reagent in metabolic research.

Cat. No.

A93119

CAS No.

1921-48-8

Thio-NADH

Thio-NADH is a biochemical reagent that serves as a reduced form of nicotinamide adenine dinucleotide (NADH) with a sulfur atom substitution. This compound exhibits critical roles in redox reactions and is essential in various metabolic pathways, acting as an electron donor. Thio-NADH is commonly utilized in enzymatic assays and studies investigating cellular respiration, energy metabolism, and oxidative stress responses in biological systems.

Cat. No.

A93338

CAS No.

111278-02-5

Hexadecanedioyl-mono-coenzyme A

Hexadecanedioyl-mono-coenzyme A is an ester product that serves as a substrate in fatty acid metabolism. This compound is involved in the synthesis and degradation of lipids, making it essential for research in metabolic pathways and energy storage mechanisms. Its role in enzymatic reactions can be leveraged in studies focusing on lipid biology and related metabolic disorders.

Cat. No.

A93408

CAS No.

6244-97-9

Sorboyl-CoA

Synonyms: Sorboyl coenzyme A; trans; trans-2,4-Hexadienoyl-CoA; trans-2,4-Hexadienoyl-coenzyme A

Sorboyl-CoA is a coenzyme A derivative that serves as an important intermediate in various metabolic pathways. It functions primarily as an acyl group donor in biochemical reactions, facilitating the synthesis and degradation of fatty acids and other metabolites. This compound is valuable for research applications focused on lipid metabolism, enzymatic activity studies, and the investigation of CoA-dependent processes.

Cat. No.

A93551

CAS No.

13019-52-8

D-threo-Biopterin

D-threo-Biopterin is a pterin compound that serves as a biochemical assay reagent. It notably enhances the chemiluminescence of Luminol when induced by the oxidant chloramine-T at a concentration of 100 μM. This compound is utilized in various research applications involving oxidative stress and reactive species detection.

Cat. No.

A93712

CAS No.

82494-50-6

S-Nitroso-CoA

Synonyms: S-Nitroso-coenzyme A; SNO-CoA; SNO-coenzyme A

S-Nitroso-CoA is a nitrosothiol derivative of coenzyme A, where the thiol group has been substituted with a nitrososulfanediyl group. This compound plays a crucial role in nitric oxide signaling pathways and has implications in redox biology. Researchers utilize S-Nitroso-CoA to investigate its effects on cellular processes such as metabolism, signal transduction, and as a potential modulator in various disease models.

Cat. No.

A93939

CAS No.

25157-96-4

3-Hydroxyadipyl-CoA

Synonyms: 3-Hydroxyadipoyl-coenzyme A

3-Hydroxyadipyl-CoA is a coenzyme A derivative that plays a crucial role in fatty acid metabolism and energy production. It participates in the synthesis and degradation of fatty acids, influencing lipid metabolism and cellular energy homeostasis. This compound is essential for studying metabolic pathways and the regulation of lipid biosynthesis in various biological systems.

Cat. No.

A96632

CAS No.

19774-86-8

3-Ketohexanoyl-CoA

3-Ketohexanoyl-CoA is a coenzyme A derivative featuring a ketone functional group. This compound is involved in fatty acid metabolism and plays a crucial role as an intermediate in the beta-oxidation pathway. Its unique structural properties make it valuable for research applications in metabolic studies and enzyme kinetics, facilitating a deeper understanding of lipid metabolism and energy production in cellular systems.

Cat. No.

A98481

CAS No.

1107039-35-9

Butyryl-Coenzyme A lithium hydrate

Synonyms: Butyryl CoA lithium hydrate

Butyryl-Coenzyme A lithium hydrate is a short-chain acyl CoA that primarily targets acyl Coenzyme A. It plays a crucial role in fatty acid metabolism and is involved in the synthesis of butyric acid. This compound is widely utilized in biochemical research concerning lipid metabolism, energy production, and as a substrate in various enzymatic reactions.

Cat. No.

A98743

CAS No.

799812-79-6

Butyryl-Coenzyme A triammonium

Synonyms: Butyryl CoA triammonium

Butyryl-Coenzyme A triammonium is an acyl-CoA derivative that serves as a key intermediate in lipid metabolism. This compound is primarily involved in the synthesis of butyric acid, playing a critical role in cellular energy metabolism and signaling pathways. It is widely utilized in biochemical research to study fatty acid metabolism and the functions of short-chain fatty acids in various biological processes.

Cat. No.

A98795

CAS No.

102282-28-0

Butyryl-Coenzyme A (trilithium)

Synonyms: Butyryl CoA (trilithium)

Butyryl-Coenzyme A (trilithium) primarily targets acyl Coenzyme A pathways. It is a short-chain acyl CoA involved in the biosynthesis of butyric acid, an important fatty acid with roles in metabolism and cell signaling. This reagent is useful for research applications focusing on fatty acid metabolism, energy production, and the regulation of gene expression related to metabolic disorders.

Cat. No.

B10900

CAS No.

9029-27-0

NAD(P)H-Nitrate reductase

NAD(P)H-Nitrate reductase is a biochemical reagent derived from Aspergillus niger, facilitating the reduction of nitrate to nitrite through a two-electron transfer mechanism. This enzyme utilizes NADPH as an electron donor, functioning as a bispecific NAD(P)H:Nitrate reductase. It is essential for studies involving nitrogen metabolism, enzymatic activity assays, and the exploration of metabolic pathways in both plant and microbial systems.

Cat. No.

B18182

CAS No.

7298-93-3

α-NAD

Synonyms: α-Nicotinamide Adenine Dinucleotide

α-NAD (α-Nicotinamide Adenine Dinucleotide) serves as a substrate for renalase and functions as an analog of β-NAD, impacting the kinetics of NAD-dependent enzymes. This compound plays a vital role as a cofactor in mitochondrial oxidation-reduction reactions, facilitating essential metabolic processes. Its application in research extends to studies involving energy metabolism and enzyme kinetics in various biological systems.

Cat. No.

B21434

CAS No.

53-57-6

NADPH

NADPH serves as a critical reducing agent involved in redox reactions, acting primarily as a coenzyme for glutathione reductase (GR), thioredoxin reductase (TrxR), and NADPH oxidase (NOX). This metabolite plays a key role in maintaining cellular redox homeostasis and exhibits antioxidant properties by facilitating the regeneration of glutathione (GSH) and thioredoxin (Trx). Additionally, NADPH is instrumental in generating superoxide anions through NOX, thereby influencing oxidative stress and immune responses. Its applications extend to the study of oxidative stress-related diseases, including cardiovascular and neurodegenerative disorders, as well as cancer, and it is integral in exploring immune regulatory mechanisms.

Cat. No.

B21700

CAS No.

85-61-0

Coenzyme A

Coenzyme A (CoASH) is a critical cofactor involved in various metabolic pathways, acting as an acyl group carrier and a carbonyl-activating agent. It plays a vital role in the citric acid cycle and fatty acid metabolism, facilitating the oxidation of pyruvate and the metabolism of both short- and long-chain fatty acids. Coenzyme A is essential for understanding metabolic processes and can be utilized in studies related to energy production and lipid metabolism.