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Acyl-CoA & Cofactors

Acyl-coenzyme A (acyl-CoA) compounds and enzyme cofactors supply activated substrates and redox carriers for assays. Acyl-CoA thioesters carry acyl groups through fatty acid metabolism and serve as substrates for acyltransferases, dehydrogenases and carboxylases. Crotonyl-CoA is a short-chain unsaturated thioester and the acyl donor for histone lysine crotonylation. Reduced nicotinamide adenine dinucleotide (NADH) and its phosphorylated form NADPH donate electrons to dehydrogenases and reductases. NADPH is offered in several salt forms, including NADPH tetrasodium salt. Sapropterin dihydrochloride is a synthetic form of tetrahydrobiopterin, the cofactor of aromatic amino acid hydroxylases and nitric oxide synthases. Coenzyme FO, a deazaflavin, is the precursor of coenzyme F420 and a light-harvesting chromophore in some DNA photolyases.

Cat. No.

A90216

CAS No.

6420-00-4

Cyclohex-1-ene-1-carbonyl-CoA

Synonyms: Cyclohex-1-ene-1-carbonyl-coenzyme A

Cyclohex-1-ene-1-carbonyl-CoA is a coenzyme A derivative that plays a crucial role in various metabolic pathways. This compound is utilized in research to study fatty acid metabolism and the synthesis of bioactive lipids. Its unique structure facilitates investigations into enzymatic reactions involving coenzyme A, providing insights into cellular processes and metabolic regulation.

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Cat. No.

A90223

CAS No.

2013545-48-5

2-Carboxypalmitoyl-CoA

Synonyms: 2-Carboxypalmitoyl-coenzyme A

2-Carboxypalmitoyl-CoA is a coenzyme A derivative that serves as a 2-carboxyacyl-CoA analogue. This compound plays a crucial role in fatty acid metabolism and can be utilized in studies examining lipid biosynthesis pathways and enzyme activities involved in acyl-CoA metabolism. Its biological activity makes it suitable for research applications in biochemistry and cellular metabolism.

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Cat. No.

A90225

CAS No.

1245946-28-4

(3S)-3-Hydroxyadipyl-CoA

Synonyms: (3S)-3-Hydroxyadipyl-coenzyme A

(3S)-3-Hydroxyadipyl-CoA is a coenzyme A derivative that plays a crucial role in various metabolic pathways. It is involved in the fatty acid synthesis and degradation processes, serving as an important intermediate in lipid metabolism. This compound is commonly utilized in biochemical research to study metabolic regulation and enzyme activity associated with CoA-dependent pathways.

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Cat. No.

A90239

CAS No.

148329-84-4

(5Z)-Dodecenoyl-CoA

Synonyms: (5Z)-Dodecenoyl-coenzyme A

(5Z)-Dodecenoyl-CoA is a coenzyme A derivative that plays a critical role in fatty acid metabolism. This compound serves as an acyl donor in biochemical reactions involving the elongation and desaturation of fatty acids. Its applications extend to studies on lipid metabolism, energy production, and the investigation of metabolic disorders.

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Cat. No.

A90263

CAS No.

76729-87-8

9-Methyldecanoyl-CoA

Synonyms: 9-Methyldecanoyl-coenzyme A

9-Methyldecanoyl-CoA is a derivative of coenzyme A, serving as a crucial metabolic intermediate. It primarily participates in fatty acid metabolism and is relevant in studies of long-chain fatty acid synthesis and degradation. This compound is valuable in research applications related to energy metabolism and lipid biochemistry.

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Cat. No.

A90265

CAS No.

1245729-61-6

6-Methylsalicylyl-CoA

Synonyms: 6-Methylsalicylyl-coenzyme A

6-Methylsalicylyl-CoA is a coenzyme A derivative that plays a crucial role in various metabolic processes. This compound is essential for the enzymatic transfer of acyl groups in metabolic pathways, making it significant in biochemical research focused on fatty acid metabolism and cellular signaling. Its study can enhance understanding of metabolic disorders and potential therapeutic targets in related fields.

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Cat. No.

A90269

CAS No.

404576-13-2

3,5-Dihydroxyphenylacetyl-CoA

Synonyms: 3,5-Dihydroxyphenylacetyl-coenzyme A

3,5-Dihydroxyphenylacetyl-CoA is a coenzyme A derivative known for its role in acyl group transfer reactions. This compound is involved in various metabolic pathways, particularly those related to phenolic compound metabolism. Its biological activity makes it useful for research in enzymology, metabolic studies, and the investigation of phenolic compound roles in biological systems.

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Cat. No.

A90277

CAS No.

711027-65-5

3-Nethylnonanoyl-CoA

Synonyms: 3-Methylnonanoyl-coenzyme A

3-Nethylnonanoyl-CoA is a derivative of coenzyme A, functioning as a key acyl-CoA compound. This reagent is essential for fatty acid metabolism and is involved in various biochemical pathways related to lipid biosynthesis. Its applications include studying metabolic processes, exploring lipid-related disorders, and investigating the roles of acyl-CoA derivatives in cellular functions.

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Cat. No.

A90284

CAS No.

157903-52-1

2-Hydroxybutanoyl-CoA

Synonyms: 2-Hydroxybutanoyl-coenzyme A

2-Hydroxybutanoyl-CoA is a derivative of coenzyme A that serves as a hydroxy fatty acyl-CoA. It plays a crucial role in lipid metabolism and is involved in the biochemical pathways of fatty acid synthesis and degradation. This reagent is valuable for research applications focused on metabolic studies and the exploration of fatty acid-related biochemical processes.

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Cat. No.

A90286

CAS No.

917-42-0

(R)-3-Hydroxylauroyl-CoA

Synonyms: (R)-3-Hydroxylauroyl-coenzyme A

(R)-3-Hydroxylauroyl-CoA is a Coenzyme A derivative featuring a 3-hydroxy fatty acyl structure. This compound plays a crucial role in lipid metabolism and is involved in the biosynthesis of complex lipids. It is useful for research applications studying metabolic pathways, fatty acid synthesis, and enzymatic reactions involving acyl-CoA compounds.

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Cat. No.

A90287

CAS No.

104732-21-0

Clofibroyl-CoA

Synonyms: Clofibroyl-coenzyme A

Clofibroyl-CoA is a coenzyme A derivative that plays a critical role in lipid metabolism. This compound functions as an acyl-CoA thioester, facilitating the activation of fatty acids for subsequent metabolic processes. Research applications include studies on lipid homeostasis, metabolic disorders, and the synthesis of bioactive lipids.

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Cat. No.

A90295

CAS No.

1883602-81-0

(3E)-Nonenoyl-CoA

Synonyms: (3E)-Nonenoyl-coenzyme A

(3E)-Nonenoyl-CoA is a coenzyme A derivative characterized by its unsaturated fatty acyl structure. This compound plays a critical role in various metabolic pathways, particularly in lipid biosynthesis and fatty acid metabolism. It is used in research applications focused on enzyme activity assays and metabolic profiling, making it valuable for studies related to cellular energy metabolism and lipid biochemistry.

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Cat. No.

A90311

CAS No.

111261-48-4

16-Hydroxypalmitoyl-CoA

Synonyms: 16-Hydroxyhexadecanoyl-coenzyme A

16-Hydroxypalmitoyl-CoA is a coenzyme A derivative characterized by its role in acylation and fatty acid metabolism. This compound is involved in biological processes such as lipid synthesis and regulation of energy homeostasis. It serves as a valuable tool for research applications studying fatty acid oxidation, metabolic pathways, and the regulation of cellular energy balance.

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Cat. No.

A90315

CAS No.

5060-32-2

Hexanoyl-coenzyme A

Synonyms: R-Hexanoyl-CoA; R-Hexanoyl coenzyme A

Hexanoyl-coenzyme A is a coenzyme A derivative known for its role in fatty acid metabolism. It acts as an acyl donor in various biochemical reactions, facilitating the elongation of fatty acid chains. This compound is essential for understanding metabolic pathways in lipid biosynthesis and can be utilized in studies focused on energy metabolism, gene regulation, and metabolic disorders.

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Cat. No.

A90326

CAS No.

1808269-27-3

betaMethoxyvaleroyl-CoA

Synonyms: betaMethoxyvaleroyl coenzyme A

Beta-Methoxyvaleroyl-CoA is a coenzyme A derivative that plays a crucial role in cellular metabolism. It serves as an important acyl donor in fatty acid metabolism and has applications in studying metabolic pathways related to lipid biosynthesis. This compound is valuable for research in biochemistry and metabolic engineering, aiding in the understanding of CoA-dependent enzymatic processes.

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Cat. No.

A90328

CAS No.

226558-54-9

(3S)-3-Hydroxyicosanoyl-CoA

Synonyms: (3S)-3-Hydroxyicosanoyl-coenzyme A

(3S)-3-Hydroxyicosanoyl-CoA is a coenzyme A derivative formed from the condensation of the thiol group of coenzyme A with the carboxy group of (3S)-hydroxyicosanoic acid. This compound plays a crucial role in lipid metabolism and fatty acid biosynthesis. It serves as an important intermediate for studying alterations in lipid signaling pathways and metabolic processes, particularly in relation to bioactive lipids in various biological systems. Researchers can utilize (3S)-3-Hydroxyicosanoyl-CoA to investigate its effects on cellular function and metabolic regulation.

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Cat. No.

A90336

CAS No.

13673-87-5

9Z,12Z,15Z-Octadecatrienoyl-CoA

Synonyms: 9Z,12Z; 15Z-Octadecatrienoyl-coenzyme A; alpha-Linolenoyl-CoA; alpha-Linolenoyl-coenzyme A

9Z,12Z,15Z-Octadecatrienoyl-CoA is a coenzyme A derivative that serves as a crucial substrate in fatty acid metabolism. This compound is involved in lipid biosynthesis and plays a role in the modulation of energy metabolism and acyl-CoA signaling pathways. It is utilized in research on metabolic pathways, lipid regulation, and enzyme activity associated with fatty acid derivatives.

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Cat. No.

A90337

CAS No.

31664-34-3

3′-Dephosphoacetyl-CoA

Synonyms: Acetyldephospho-CoA

3′-Dephosphoacetyl-CoA, a coenzyme A derivative, plays a critical role in metabolic pathways by participating in acetylation reactions. This compound is vital for studying acetyl-CoA metabolism and its regulatory mechanisms in cellular processes. Its applications extend to research on enzymatic activity and metabolic flux analysis in diverse biological systems.

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Cat. No.

A90357

CAS No.

117249-46-4

(R)-3-Hydroxyvaleryl-CoA

Synonyms: (3R)-Hydroxyvaleryl-coenzyme A

(R)-3-Hydroxyvaleryl-CoA is a Coenzyme A derivative that serves as a 3-hydroxy fatty acyl-CoA. It is synthesized through the condensation of the thiol group of coenzyme A with the carboxy group of (R)-3-hydroxypentanoic acid. This compound is important for metabolic studies involving fatty acid metabolism and plays a role in the biosynthesis of various lipids. Researchers utilize (R)-3-Hydroxyvaleryl-CoA to explore its biological activities and mechanisms in cellular processes.

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Cat. No.

A90367

CAS No.

2245809-15-6

4-Oxooctanoyl-CoA

Synonyms: 4-Oxooctanoyl-coenzyme A

4-Oxooctanoyl-CoA is a coenzyme A derivative that plays a crucial role in fatty acid metabolism and energy production. It serves as an important substrate in enzymatic reactions involving the acylation of various biomolecules. This compound is utilized in research applications focused on metabolic pathways, lipid biosynthesis, and the regulation of cellular energy homeostasis.

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Cat. No.

A90371

CAS No.

1383686-26-7

[Hydroxy(phenyl)methyl]succinyl-CoA

Synonyms: [Hydroxy(phenyl)methyl]succinyl-coenzyme A

[Hydroxy(phenyl)methyl]succinyl-CoA is a coenzyme A derivative that plays a crucial role in various metabolic pathways. This compound serves as a key intermediate in cellular processes, facilitating the transfer of acyl groups in the synthesis and degradation of fatty acids and amino acids. Its unique structure can be utilized in biochemical studies to investigate metabolic regulation and enzyme functionality in various cellular contexts.

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Cat. No.

A90376

CAS No.

1315548-99-2

Flurbiprofen-CoA

Synonyms: Flurbiprofen-coenzyme A

Flurbiprofen-CoA is a coenzyme A derivative that serves as a key intermediate in the metabolism of flurbiprofen, a nonsteroidal anti-inflammatory drug (NSAID). This compound plays an essential role in the modulation of inflammation and pain pathways. It is valuable for research applications involving enzymatic assays, drug metabolism studies, and the exploration of novel therapeutic strategies targeting inflammatory diseases.

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Cat. No.

A90379

CAS No.

88978-30-7

S-(Dimethylarsinite)-CoA

Synonyms: S-(Dimethylarsinite)-coenzyme A

S-(Dimethylarsinite)-CoA is a coenzyme A derivative that serves as a key intermediate in arsenic metabolism. This compound is known to participate in biochemical reactions related to arsenic detoxification and bioactivation processes. Its study is essential for understanding the mechanistic pathways of arsenic's biological effects and potential therapeutic interventions in arsenic-related diseases.

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Cat. No.

A90380

CAS No.

429685-08-5

(3E)-tetradecenoyl-CoA

Synonyms: (3E)-tetradecenoyl-coenzyme A

(3E)-tetradecenoyl-CoA is an unsaturated fatty acyl-CoA derivative that acts as a substrate for various enzymes involved in fatty acid metabolism. This compound plays a crucial role in lipid biosynthesis and energy production, making it valuable in metabolic studies. It is also utilized in research related to cellular signaling and the regulation of fatty acid oxidation.

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Cat. No.

A90393

CAS No.

4752-14-1

trans-9-Octadecenoyl-CoA

Synonyms: trans-9-Octadecenoyl-coenzyme A

Trans-9-Octadecenoyl-CoA is a coenzyme A derivative that plays a crucial role in lipid metabolism and fatty acid biosynthesis. This compound is involved in the acylation of proteins and the synthesis of various bioactive lipids, making it a valuable reagent for studying metabolic pathways. Its biological activity is important for research applications related to lipid biology, cellular metabolism, and enzyme regulation.

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