Catalog No.
Product Name
Application
Product Information
Citations
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Drug Intermediate
5,6-Dimethoxyindan-1-one is a versatile drug intermediate employed in the synthesis of diverse active pharmaceutical ingredients. It has applications in the development of antiviral compounds and acetylcholinesterase butyrylcholinesterase inhibitors. This reagent serves as a critical building block in medicinal chemistry, facilitating the exploration of new therapeutic agents. -
Drug Intermediate
7(Z),10(Z),13(Z)-Hexadecatrienoic acid, also known as Roughanic acid, functions as a drug intermediate in organic synthesis. This ω-3 polyunsaturated fatty acid (PUFA), extracted from the leaves of S. olusatrum, plays a crucial role in the biosynthesis of jasmonic acid. Its applications in chemical research chiefly involve the investigation of plant hormone pathways and the exploration of bioactive lipid compounds in various biological systems. -
Drug Intermediate
Triacetylphloroglucinol is a symmetric three-dimensional bridged ligand that serves as a useful drug intermediate in organic synthesis. It facilitates the production of various compounds, including trinuclear vanadium Schiff base complexes, copper complexes, and anthelmintics. Its applications extend to the development of pharmacologically relevant materials and coordination chemistry. -
Drug Intermediate
3-(2-Chloroacetyl)-1H-indole-5-carbonitrile serves as an important drug intermediate, facilitating the synthesis of diverse active pharmaceutical compounds. This compound is characterized by its unique indole structure, which contributes to its utility in medicinal chemistry research. Its versatility in organic synthesis makes it a valuable reagent for developing new therapeutic agents. -
Drug Intermediate
(Z)-5-(4-Iodobenzylidene)-2-thioxothiazolidin-4-one serves as a crucial drug intermediate in the synthesis of diverse active pharmaceutical compounds. This compound exhibits structural characteristics that facilitate various chemical reactions, making it valuable in medicinal chemistry research. Its applications extend to the development of novel therapeutic agents with potential biological activity. -
Drug Intermediate
Cyanoacetohydrazide serves as a pharmaceutical intermediate, primarily utilized in the synthesis of acylhydrazide hydrazone derivatives. These derivatives have demonstrated notable antibacterial and anti-tumor activities, making cyanoacetohydrazide a valuable compound in drug development and medicinal chemistry research. Its versatile applications in synthesizing bioactive compounds contribute significantly to advancing therapeutic strategies. -
Drug Intermediate
3-(4-Chlorophenoxy)-4-methylaniline serves as a critical drug intermediate utilized in the synthesis of a range of active pharmaceutical ingredients. This compound is integral in the development of various therapeutic agents, enabling effective chemical transformations in medicinal chemistry. Its unique structural features allow for versatile applications in pharmaceutical research and development. -
Drug Intermediate
2,3,4-Tri-O-acetyl-β-D-glucuronide methyl ester is a synthetic intermediate utilized in the preparation of prodrug forms of the antitumor antibiotic Daunomycin. This compound exhibits crucial functionalities in glycosylation reactions, facilitating drug development and optimization. Its applications in medicinal chemistry and pharmaceutical research make it a valuable reagent for advancing therapeutic formulations in oncology research. -
Drug Intermediate
42-O-(2-Azidoethyl)-Rapamycin is an azide-modified derivative of Rapamycin, functioning as an important drug intermediate for synthetic applications. It facilitates the development of Rapamycin derivatives, which are of interest in various therapeutic contexts, particularly in cancer research and immunosuppression studies. This compound's unique structure allows for further modifications that can enhance biological activity and specificity in target engagement. -
Drug Intermediate
Methyl (3S,6R)-6-methyl-3-piperidinecarboxylate L-tartaric acid salt serves as a versatile drug intermediate in the synthesis of various bioactive compounds. This compound plays a crucial role in the preparation of pharmaceutical agents, contributing to diverse chemical structures and medicinal properties. Its application is significant in the fields of medicinal chemistry and drug development. -
Drug Intermediate
6,7-Dibromoquinoline-5,8-dione is a versatile drug intermediate utilized in the synthesis of a variety of biologically active compounds. This compound serves as a crucial building block in medicinal chemistry and pharmaceutical development, facilitating the creation of novel therapeutic agents. Its incorporation into chemical reactions can lead to the development of compounds with potential applications in diverse areas of drug discovery and development. -
Drug Intermediate
Triphenylene is a highly symmetrical polycyclic aromatic hydrocarbon that serves as a valuable drug intermediate. It facilitates the synthesis of triphenyl polycyclic aromatic hydrocarbons (PAHs), which are significant in various chemical applications. Notably, Triphenylene demonstrates no carcinogenic activity in mouse skin application experiments, supporting its use in safe pharmaceutical development and research. -
Drug Intermediate
4-Methylbenzothioamide is a cyclic thioamide used as a building block in drug discovery chemistry. This compound serves as an important intermediate in the synthesis of various pharmaceutical agents. Its unique structure allows for the modification of bioactive molecules, facilitating the development of novel therapeutics. -
Drug Intermediate
N,N-Dimethyl-L-valine is a synthetic amino acid derivative commonly used as a drug intermediate in pharmaceutical synthesis. This compound serves as a valuable building block in the development of various bioactive molecules, facilitating the creation of novel therapeutic agents. Its structural properties contribute to the modulation of biological activity, making it an essential reagent in chemical research and drug discovery applications. -
Drug Intermediate
tert-Butyl chlorosulfonylcarbamate compound with 1,4-diazabicyclo[2.2.2]octane (1:2) serves as a versatile drug intermediate, facilitating the synthesis of a range of bioactive molecules. This compound is particularly useful in the development of pharmaceuticals due to its ability to participate in multistep synthesis reactions, enhancing chemical pathways for novel drug discovery and development. Its unique structure enables precise functionalization, making it an essential reagent in chemical research and medicinal chemistry applications. -
Drug Intermediate
2,2-Dibenzyl-1,3-propanediol serves as a crucial drug intermediate in the synthesis of various pharmacologically active compounds. It contributes to the formation of complex molecular structures, facilitating the development of new therapeutics. This compound is valuable in medicinal chemistry and drug development applications, where it supports the exploration of innovative treatments. -
Drug Intermediate
Methyl 9H-xanthene-9-carboxylate serves as a crucial intermediate in the synthesis of diverse active pharmaceutical compounds. This compound plays an essential role in the development of xanthene derivatives, which are of significant interest in chemical and medicinal research. Its utility in drug synthesis supports studies aimed at optimizing pharmacological properties and biological activities. -
Drug Intermediate
4-Chlorophenyl-2-pyridinylmethanol is a versatile synthetic intermediate primarily utilized in pharmaceutical synthesis. This compound acts as a building block in the development of various bioactive molecules, facilitating the production of targeted therapeutics. Its efficacy in chemical reactions makes it a valuable reagent for researchers engaged in drug discovery and development. -
Drug Intermediate Control
2-Pyrimidinepropanoic acid is a synthetic intermediate primarily utilized in pharmaceutical synthesis. This compound serves as a key building block in the development of various bioactive molecules and drug candidates, facilitating research in medicinal chemistry. Its role in the modification of bioactive compounds makes it valuable for applications in drug discovery and development. -
MRX-I Prodrug Intermediate
Contezolid phosphoramidic acid is a key intermediate in the synthesis of MRX-I, an antibacterial oxazolidinone agent. This compound plays a critical role in the development of proagents designed to combat bacterial infections. Its relevance in medicinal chemistry makes it an essential reagent for research applications focused on antibiotic efficacy and development. -
Drug Intermediate
5-Ethoxy-4-methyloxazole is a chemical intermediate primarily utilized in the synthesis of pharmaceutical compounds. This heterocyclic compound contributes to the development of various drug candidates by serving as a building block in organic synthesis. Its structural characteristics support research in medicinal chemistry and the design of novel therapeutics. -
Drug Intermediate
tert-Butyl 2-(5-chloro-2,2'-dioxospiro[indole-3,3'-pyrrolidine]-1-yl)acetate serves as an important intermediate in the synthesis of potent DP2 receptor antagonists derived from a novel spiro-indolinone framework. This compound is significant for its role in drug discovery, particularly in the development of therapeutics aimed at modulating immune responses and inflammation pathways. Researchers utilize this intermediate to facilitate the creation of compounds with potential clinical applications in treating allergic and inflammatory diseases. -
Drug Intermediate
Stemmadenine is a strychnos-type monoterpenoid indole alkaloid that functions as a crucial biosynthetic precursor in the formation of monoterpenoid indole alkaloid structures. Its primary mechanism involves contributing to the synthesis of complex alkaloids, making it valuable in drug development and research into natural product synthesis. Stemmadenine is utilized extensively in studies focused on the biosynthetic pathways of alkaloids and their potential therapeutic applications. -
Drug Intermediate
(2R,3S,4R,5R)-GlcAc-GlcA is a hexose derivative primarily utilized as a drug intermediate in the synthesis of antibody-drug conjugate (ADC) linkers. Its structural features contribute to the development of more effective targeted therapies in oncology research. This compound serves as a valuable building block in the formulation of bioconjugates, enhancing the specificity and efficacy of therapeutic agents. -
Drug Intermediate
2-Phenylacrylonitrile is a versatile pharmaceutical intermediate that serves as a precursor in the synthesis of various compounds. Its derivatives are utilized in cancer research, particularly in the development of cancer therapeutics and mechanisms of action studies. This compound provides essential building blocks for the exploration of anticancer agents and their biological activity. -
Drug Intermediate
Fmoc-PNA-maleimide-OH is a Fmoc-protected peptide nucleic acid monomer that incorporates a maleimide moiety, enabling selective thiol-reactive conjugation. This compound facilitates the construction of peptide nucleic acid (PNA) conjugates, which are valuable in molecular assembly and bioconjugation applications. Its unique functionalization allows for enhanced versatility in the design of nucleic acid-based tools for research and therapeutic development. -
Drug Intermediate
Erlotinib lactam impurity is a chemical precursor of the tyrosine kinase inhibitor erlotinib. This compound serves as an important intermediate in the synthesis of anti-cancer therapeutics, particularly in the study of targeted therapies for non-small cell lung cancer. Its role in drug development makes it a valuable reagent for research applications focused on kinase inhibition and related signaling pathways. -
Drug Intermediate
3-(Trimethylsilyl)-1-propanesulfonic acid sodium functions as a drug intermediate, facilitating various chemical reactions. This compound serves as a versatile reagent in the synthesis of peptides, proteins, and nucleic acids. Its efficacy in stabilizing reactive intermediates makes it a valuable tool for researchers in biochemical and pharmaceutical applications. -
Drug Intermediate
5-Br-4-Cl-Pyrrolo-pyroxypyridine serves as a synthetic intermediate for molecular glues. It is particularly relevant in the synthesis of GSPT1 degrader-9, facilitating targeted protein degradation. This compound is essential for research applications focused on proteostasis and the modulation of protein interactions. -
Drug Intermediate
4-Hydroxy-3,3-dimethylcyclohexanone serves as a crucial intermediate in the synthesis of human acetylcholinesterase (hAChE) inhibitors. Its role in the development of hAChE inhibitors makes it significant for research in neuropharmacology and disease models related to cholinergic dysfunction. This compound's unique structural properties facilitate the exploration of therapeutic agents targeting cognitive disorders. -
Drug Intermediate
H-Aeg(Fmoc)-OBzl hydrochloride is an Fmoc-protected aminoethylglycine derivative with a benzyl ester moiety. It serves as a versatile drug intermediate, facilitating the synthesis of peptide nucleic acids and protected oligomers. This compound is valuable in various research applications, including peptide synthesis and molecular biology studies. -
Drug Intermediate
LY280748 is a potent imidazolate receptor ligand, functioning primarily as a drug intermediate. This compound exhibits significant biological activity, making it a valuable tool in pharmacological research and development. Its application spans various studies focused on receptor-mediated signaling pathways and the synthesis of novel therapeutic agents. -
Drug Intermediate
GA44 is a C20-gibberellin that serves as an intermediate in the early 13-hydroxylation pathway of gibberellin biosynthesis. This compound plays a critical role in the synthesis of biologically active gibberellins, which are important regulators of plant growth and development. GA44 is utilized in research applications focusing on plant hormone signaling and metabolism studies. -
Drug Intermediate
H-Aeg(Fmoc)-OH hydrochloride is an Fmoc-protected aminoethylglycine monomer that features a free carboxyl group. This reagent serves as a versatile building block for peptide nucleic acid synthesis, facilitating the construction of PNA oligomers. Its chemical structure supports the incorporation of aminoethylglycine into various bioconjugates, making it valuable in nucleic acid research and related fields. -
Drug Intermediate
N,N'-bis-Cbz-β-Alethine is an active ester that serves as a crucial intermediate in the synthesis of β-alethine. β-Alethine has been shown to induce cell differentiation and exhibits potential anti-tumor properties. The conversion of N,N'-bis-Cbz-β-Alethine to β-alethine is achieved through the removal of the carbobenzoxy (CBZ) groups using hydrogen bromide in glacial acetic acid. This compound is valuable for research focused on cell differentiation mechanisms and anti-cancer drug development. -
Drug Intermediate
Azidoethyl-oxime-Glucose-GalNAc serves as a versatile drug intermediate, primarily aimed at synthesizing disaccharide linkers. This compound plays a crucial role in the development of glycan site-directed antibody-drug conjugates (ADCs), facilitating targeted delivery in therapeutic applications. Its unique chemical structure allows for efficient modification and incorporation into complex carbohydrates, making it essential for advancing glycoscience research and drug development. -
Drug Intermediate
K-13 is a cyclic peptide compound that serves as a valuable drug intermediate through its role in organic synthesis. Its production involves a highly efficient synthetic route utilizing intermolecular and intramolecular Negishi cross-coupling reactions. This streamlined synthesis approach makes K-13 a significant reagent for research applications in drug development and peptide chemistry. -
Drug Intermediate
Methoxycarbonyl isocyanate serves as a versatile drug intermediate primarily utilized in organic synthesis. Its reactive isocyanate group allows for the formation of various carbamates and ureas, making it valuable in the development of pharmaceutical compounds. This reagent is essential for studying and optimizing synthetic pathways in drug discovery and development. -
Drug Intermediate
Guaietolin is an organic synthesis intermediate primarily used in the development of sulfonamide esters that exhibit carbonic anhydrase inhibitory activity. It serves as a significant marker of hypertension, as its levels are notably reduced in plasma metabolites of affected individuals. Guaietolin is applicable in research focused on glaucoma and hypertension, providing a valuable tool for investigating these cardiovascular and ocular conditions. -
Drug Intermediate
Bimatoprost isopropyl ester acts as a drug intermediate with a specific focus on the prostaglandin F2α analogs. It is characterized by a double bond at the 13-14 position and an inverted hydroxyl group at C-15. Notably, this compound has demonstrated significant biological activity, exhibiting an IC50 of 30 nM in FP receptor binding assays, indicating its potential role as an impurity in latanoprost formulations. Additionally, in vivo studies revealed that a dose of 3 μg can lead to a 1.9 mmHg decrease in intraocular pressure in normotensive cynomolgus monkeys, making it a valuable reagent for research involving ocular therapies. -
Drug Intermediate
Fmoc-Aeg-OtBu is a versatile intermediate used in solid-phase peptide synthesis. It acts as a building block for the introduction of pseudoproline motifs and backbone modifications, enhancing the stability and folding properties of peptides. This compound is essential for researchers developing peptide therapeutics and studying protein structure and function. -
Drug Intermediate
1-epi-Regadenoson ethyl ester is a key intermediate in the synthesis of the α-isomer impurity of Regadenoson, a highly selective agonist for the adenosine A2A receptor. This compound is essential for research involving adenosine receptor biology and contributes to the understanding of cardiovascular function and cellular signaling pathways. Its application extends to the development and analysis of therapeutic agents targeting adenosine receptors. -
Drug Intermediate
LBA-NHS is a derivative of lactobionic acid (LBA) designed as a drug intermediate. It functions by enabling the modification of lipids and acts as a coating for biological materials, enhancing the efficient and specific binding of LBA to carrier molecules. This compound is valuable in research applications involving drug delivery systems and biomaterials engineering. -
Drug Intermediate
5β-Dihydrocortisone acetate serves as a crucial intermediate in the synthesis of tetrahydrocortisone 3-glucuronide. This compound plays a significant role in biochemical research and pharmaceutical development, particularly in the study of corticosteroid metabolism and glucuronidation processes. Its use can facilitate investigations into the pharmacokinetics of glucocorticoids and their conjugates, contributing to a better understanding of steroid biochemistry. -
Drug Intermediate
1-Amino-3-(phosphonooxy)-2-propanone acts as a crucial drug intermediate in the synthesis of vitamin B6. This compound facilitates biochemical reactions essential for the production of vitamin B6 derivatives, contributing to studies in nutrition and metabolism. Its application in synthetic pathways enhances research related to vitamin synthesis and potential therapeutic developments. -
Drug Intermediate
AldoView precursor-1 is a crucial intermediate in the synthesis of the radioactive PET tracer [18F] AldoView. This compound serves as a selective tracer for imaging aldosterone synthase activity, making it valuable in the study of primary hyperaldosteronism. Its application facilitates non-invasive imaging and further research into aldosterone-related disorders. -
Drug Intermediate
Citreomontanin, an α-Pyrone polyketide, serves as a key drug intermediate in the synthesis of Citreoviripyrone A. Isolated from the mycelium of endophytic Penicillium species in Catharanthus roseus, Citreomontanin plays a critical role in facilitating research on compounds with biological activity. Notably, Citreoviripyrone A exhibits moderate inhibitory effects on the proliferation of HCT116 colorectal cancer cells, highlighting its potential utility in cancer research and drug development. -
Drug Intermediate
Fmoc-Aeg-OMe hydrochloride is a methyl ester derivative of Fmoc-protected aminoethylglycine, primarily used as a drug intermediate in chemical synthesis. This compound plays a crucial role in the synthesis of polyamide nucleic acids, facilitating research in nucleic acid chemistry and related fields. Its unique structure and properties make it valuable for developing novel therapeutic agents and exploring biomolecular interactions. -
Drug Intermediate
Valone is a critical intermediate in the synthesis of diorganotin(IV) complexes. Its unique chemical properties facilitate the creation of organotin compounds, which are essential in various applications, including agricultural and pharmaceutical research. This reagent serves as a fundamental building block for the development of advanced materials and bioactive substances in chemical research. -
Drug Intermediate
5-Bromo-1,2-difluoro-3-methoxybenzene serves as a crucial drug intermediate in synthetic chemistry. It functions as a precursor for the development of glucocorticoid receptor (GR) ligands, enabling the exploration of GR-targeted therapies. This compound is applicable in pharmaceutical research for the synthesis of novel therapeutic agents.
