Drug Metabolite

Cat. No.

A70190

CAS No.

494-90-6

Menthofuran, 84%

Menthofuran is a proximate toxic metabolite of (R)-(+)-Pulegone, primarily acting as a modulator of essential oil biosynthesis in peppermint. This compound regulates monoterpene reductase activity, influencing the production of key components in essential oils. Menthofuran is valuable for research on metabolic pathways in mint species and studies investigating the biochemical effects of pulegone derivatives.

Cat. No.

A70221

CAS No.

75504-34-6

Tamoxifen N-oxide

Tamoxifen N-oxide is a metabolite of the selective estrogen receptor modulator (SERM) Tamoxifen. This compound exhibits estrogen receptor antagonistic activity and has been implicated in the pharmacological effects of Tamoxifen in breast cancer treatment. Tamoxifen N-oxide is utilized in research applications focusing on estrogen receptor signaling, cancer biology, and drug metabolism studies.

Cat. No.

A70518

CAS No.

37577-22-3

(-)-Norfenfluramine (l-Norfenfluramine)

Synonyms: l-Norfenfluramine

(-)-Norfenfluramine is a metabolite of Fenfluramine, functioning primarily as a serotonin receptor modulator. It has demonstrated effectiveness in reversing abnormal locomotor activity in zebrafish models. This compound is particularly useful in the study of epilepsy and related neurological disorders.

Cat. No.

A70770

CAS No.

71368-66-6

8-Aminoclonazolam

8-Aminoclonazolam is a benzodiazepine metabolite known for its potential effects on the central nervous system. It functions primarily as a modulator of the GABAergic system, influencing neurotransmitter activity to produce anxiolytic and sedative effects. This compound is of interest in research focusing on the pharmacokinetics and neuropharmacology of benzodiazepines, as well as in studies assessing drug metabolism and psychotropic drug development.

Cat. No.

A72839

CAS No.

15978-08-2

D-Fructose 1-phosphate

D-Fructose 1-phosphate is an essential intermediate in the fructose metabolic pathway, functioning primarily as a signaling molecule that integrates fructose and glucose metabolism. It acts as an allosteric modulator, counteracting the inhibitory influence of the glucokinase-regulatory protein complex, thus regulating hepatic glucose metabolism at the substrate level. This compound is valuable for research in metabolic regulation and diabetes studies, facilitating a deeper understanding of carbohydrate metabolism.

Cat. No.

B11107

CAS No.

182322-62-9

Genistein 7-sulfate

Genistein 7-sulfate is a metabolite of the isoflavonoid genistein, primarily functioning as a modulator of estrogen activity. It has been shown to reduce the activity of estrogen agonists in estrogen-sensitive MCF-7 breast cancer cells. Additionally, at concentrations of 10 μM and higher, Genistein 7-sulfate can promote cell growth, making it a valuable compound for research in hormone-related pathways and cancer biology.