Alkynes

UDP-2-alkyne-GlcNAc is a derivative of UDP-GlcNAc, targeting glycosylation processes. This compound serves as a crucial tool for the remodeling of cell surface glycans, enabling researchers to study glycan structures and functions in various biological contexts. It is particularly useful in applications such as metabolic labeling and click chemistry for the visualization of glycoproteins and glycoconjugates.

16:0(Alkyne)-18:1 PE is a clickable phospholipid designed for use in click chemistry applications. This compound facilitates the conjugation of biomolecules, allowing for the study of lipid interactions and cellular uptake dynamics. Its unique alkyne functionality enables efficient labeling and tracking of phospholipid structures in various biological systems, making it a valuable tool for researchers in lipidomics and membrane biology.

4-Oxo-2-Nonenal Alkyne is a functionalized lipid electrophile designed for click chemistry applications. It facilitates the conjugation to exosomes through the reaction of amino and aldehyde groups. This reagent is particularly useful for the determination and characterization of tumor-derived exosomes in various biological research settings.

DOTA-PEG4-alkyne is a bifunctional linker designed for efficient conjugation with radionuclides. It facilitates the creation of radiolabeled biomolecules, enabling precise imaging and therapeutic applications in molecular biology and nuclear medicine. Its PEGylated structure enhances solubility and biocompatibility, making it suitable for various research applications, including drug delivery and targeted therapy.

C16:0(Alkyne) L-carnitine is an acyl carnitine lipid that features a terminal alkyne group, serving as a valuable tool for click chemistry applications. This reagent facilitates specific reactions with azide-containing compounds in the presence of a copper catalyst, enabling efficient linkage in various biochemical studies. Its unique structure allows for functionalization and the investigation of lipid-related biological processes, making it suitable for research in cellular metabolism and lipid signaling.

16:0(Alkyne)-18:1 PC is a clickable phospholipid that enables the study of lipid metabolism and cellular membrane dynamics. This compound serves as a versatile tool for lipid labeling in biological research, facilitating the investigation of membrane-associated processes. It is particularly useful in studies involving lipid droplet formation, membrane trafficking, and the role of phospholipids in cell signaling pathways.

27-Alkyne cholesterol is a modified lipid featuring an omega-terminal alkyne, enabling its application as a biochemical assay reagent. This compound participates in click chemistry with azide-containing reagents in the presence of copper catalysts, facilitating highly specific linking reactions. As a versatile tool for investigating cellular cholesterol metabolism and localization, 27-alkyne cholesterol supports various detection methods, including mass spectrometry and fluorescence microscopy. Its sensitive and user-friendly properties make it ideal for diverse research applications in lipid biology.

Alkyne Phosphoramidite, 5'-terminal is a specialized reagent designed for the synthesis of oligo-nucleotides. This compound enables the incorporation of alkyne groups at the 5' terminus, facilitating subsequent functionalization and applications in bioconjugation strategies. It is invaluable for researchers focused on nucleic acid chemistry and related biotechnological applications.

Alkyne sphinganine is a biochemical assay reagent that features a terminal alkyne group, enabling the selective tagging of protein-lipid complexes through click chemistry. This compound facilitates a highly specific reaction with azide-containing reagents in the presence of a copper catalyst, allowing for the visualization and proteomic profiling of protein-sphingolipid interactions in living cells. Its application in metabolic labeling contributes significantly to the understanding of lipid biology and cellular dynamics.

Alkyne amidite, hydroxyprolinol is a phosphorous amide monomer designed for oligonucleotide synthesis. This reagent facilitates the incorporation of alkyne functionalities into nucleic acid structures, enabling various applications in bioconjugation and probe development. Its unique properties make it a valuable tool for researchers focused on nucleic acid chemistry and related fields.

Alkyne maleimide is a bifunctional linker reagent characterized by a terminal maleimide group and a propargyl group. The maleimide group effectively reacts with thiol groups to form stable covalent bonds, facilitating the conjugation of biomolecules containing thiols. Additionally, the propargyl group enables specific labeling of azide-containing biomolecules through Click Chemistry. This reagent is widely used in biochemical assays and protein labeling applications.

19-Alkyne Cholesterol is an alkyne-modified derivative of cholesterol that serves as a valuable tool for studying cholesterol localization and subcellular distribution in cellular environments. This compound facilitates the investigation of cholesterol dynamics and its role in membrane biophysics. It is particularly useful in biochemistry and cell biology research applications, enabling insights into cholesterol-related processes and signaling pathways.

Mal-amido-PEG5-alkyne functions as a biochemical assay reagent featuring a maleimide group and an alkyne component. This PEG-based linker enhances solubility in aqueous environments while enabling versatile coupling reactions. The alkyne moiety can engage in copper-catalyzed azide-alkyne Click Chemistry, resulting in a stable triazole bond with azide-containing biomolecules. Additionally, the maleimide group facilitates covalent attachment to thiol-containing compounds, making it ideal for applications in bioconjugation and protein labeling studies.

Biotinamide-C3-PEG3-C-alkyne is a biotin-conjugated polyethylene glycol (PEG) reagent featuring a terminal alkyne. This compound facilitates efficient coupling through Click Chemistry with various azide-containing molecules, such as BCN and DBCO. It is primarily utilized in biochemical assays for labeling and detecting biomolecules, enhancing the study of biological processes and interactions.

BP Fluor 488 Alkyne is a fluorescent dye specifically designed for labeling in Click Chemistry reactions. It conjugates effectively with azide-modified biomolecules, including antibodies, proteins, peptides, and amino-modified oligonucleotides. With an excitation peak at 499 nm and emission peak at 520 nm, this dye allows for enhanced visualization in applications such as microscopy and flow cytometry. BP Fluor 488 Alkyne is a pure 5-sulfonated rhodamine derivative, providing consistent results free from lot-to-lot variation.

BP Fluor 430 Alkyne is a green-fluorescent alkyne-activated probe designed for the imaging of azide-containing biomolecules with moderate to high abundance. It utilizes a copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction to produce a stable triazole linker. This probe exhibits bright and photostable fluorescence, optimally excited near 430 nm, and is water-soluble, maintaining pH-independent fluorescence across a wide range. Applications include cellular imaging and visualization of biomolecular interactions.

BP Fluor 594 alkyne is a fluorescent dye designed for the specific imaging of azide-containing biomolecules. This probe utilizes a copper-catalyzed azide-alkyne cycloaddition (CuAAC) mechanism to react with azides, resulting in the formation of a stable triazole linkage. Its bright red fluorescence makes it an effective tool for various biological research applications, particularly in tracking biomolecular interactions and localization studies.

BP Fluor 647 Alkyne is a fluorescent dye characterized by its bright green fluorescence and optimal excitation with 633 and 650 nm Argon lasers. The alkyne moiety enables efficient reactions with azides through copper-catalyzed Click Chemistry. With its four sulfonate groups, this dye demonstrates excellent water solubility and reduced aggregation across a pH range of 4 to 10. BP Fluor 647 Alkyne is ideal for applications in protein and antibody labeling, as well as nucleic acid studies, allowing for high labeling density.

BP Fluor 405 alkyne triTEA is a blue-fluorescent dye that serves as a versatile labeling reagent in multi-color applications, including flow cytometry and super-resolution microscopy techniques like STORM. It exhibits optimal excitation around the 407 nm spectral line of krypton lasers and the 408 nm violet laser diode. This dye participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC), yielding a stable triazole linker upon reaction with azides. Additionally, a copper-free alternative, BP Fluor 405 DBCO, is available for applications sensitive to copper presence.

Itaconate-alkyne is a bioorthogonal probe designed for quantitative and site-specific chemoproteomic profiling of itaconation in live cells. As a functional analogue of itaconate, it exhibits comparable anti-inflammatory effects while facilitating the labeling of itaconate's genuine biological targets. This reagent incorporates an alkyne group, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules, making it a valuable tool for studying metabolic processes and inflammatory responses.

(E)-2-Hexadecenal alkyne is a fluorescent dye that serves as a chemical probe to investigate the cellular targets of 2-trans-Hexadecenal. This compound covalently modifies a range of proteins within cells, making it an effective tool for studying diseases associated with lipid metabolism. Researchers can utilize this reagent to gain insights into protein interactions and signaling pathways influenced by lipid-derived compounds.

Thiophosphoro alkyne dichloridate is a histidine coupling agent that functions as a thio-phosphonyl dichloride reagent. It enables selective covalent coupling with histidine residues, facilitating the development of protein function probes. This compound is particularly useful in studies related to protein phosphorylation and the exploration of histidine-based modifications in biological systems.

Docosahexaenoic acid alkyne is a derivative of docosahexaenoic acid (DHA) characterized by the presence of a terminal ω-alkyne functional group. This compound serves as a valuable tool for studying lipid metabolism and fatty acid signaling pathways in various biological systems. It can be utilized in click chemistry applications, enabling the labeling and visualization of DHA-containing molecules in cellular environments.