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EHT 5372
Catalog No. A12586 DYRK inhibitorEHT 5372 is a strong inhibitor of DYRK??s family kinases, with IC50s of 0.22, 0.28 nM for DYRK1A and DYRK1B, respectively. Learn More -
LDN-192960 hydrochloride
Catalog No. A21390 DYRK2 inhibitorLDN-192960 hydrochloride is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM, respectively. Learn More -
GSK-626616
Catalog No. A19273 DYRK3 inhibitorGSK-626616 is a potent, orally bioavailable inhibitor of DYRK3 (IC50=0.7 nM). Learn More -
Paprotrain
Catalog No. A20346 MKLP-2 inhibitorPaprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM. Learn More -
ID 8
Catalog No. A12922 DYRK inhibitorID-8 is a DYRK inhibitor. ID 8 also stimulates proliferation at a steady rate (observed in serum-free media supplemented with 10 μM over a 30 day period). Learn More -
AZ191
Catalog No. A14314 DYRK inhibitorAZ191 is a potent and selective DYRK1B inhibitor with IC50 of 17 nM, about 5- and 110-fold selectivity over DYRK1A and DYRK2. Learn More -
Mirk-IN-1
Catalog No. A16255 Dyrk1B inhibitorMirk-IN-1 is a potent inhibitor of Dyrk1B(Mirk kianse) and Dyrk1A with IC50 of 68±48 nM and 22±8 nM respectively. Learn More -
LDN-192960
Catalog No. A21546 DYRK2 inhibitorLDN-192960 is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM, respectively. Learn More
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