DYRK
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LDN-192960 hydrochloride
Catalog No. A21390 DYRK2 inhibitorLDN-192960 hydrochloride is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM, respectively. Learn More -
EHT 5372
Catalog No. A12586 DYRK inhibitorEHT 5372 is a strong inhibitor of DYRK??s family kinases, with IC50s of 0.22, 0.28 nM for DYRK1A and DYRK1B, respectively. Learn More -
sAJM589
Catalog No. A18429 Myc inhibitorsAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM. Learn More -
10074-G5
Catalog No. A17169 c-Myc Inhibitor10074-G5 is a c-Myc inhibitor by inhibiting c-Myc/Max heterodimer formation and inhibiting its transcriptional activity with IC50 value of 146 μM. Learn More -
ML327
Catalog No. A17009 MYC inhibitorML327 is a blocker of MYC. ML327 mediated transcriptional de-repression of E-cadherin and inhibition of epithelial-to-mesenchymal transition. Learn More -
KJ Pyr 9
Catalog No. A16324 MYC inhibitorKJ Pyr 9 is a novel small-molecule inhibitor of MYC, KJ-Pyr-9, from a Krhnke pyridine library. Learn More -
10058-F4
Catalog No. A13725 c-Myc-Max inhibitor10058-F4 is a c-Myc inhibitor that prevents c-Myc/Max dimerization. Learn More -
Mirk-IN-1
Catalog No. A16255 Dyrk1B inhibitorMirk-IN-1 is a potent inhibitor of Dyrk1B(Mirk kianse) and Dyrk1A with IC50 of 68±48 nM and 22±8 nM respectively. Learn More -
AZ191
Catalog No. A14314 DYRK inhibitorAZ191 is a potent and selective DYRK1B inhibitor with IC50 of 17 nM, about 5- and 110-fold selectivity over DYRK1A and DYRK2. Learn More -
ID 8
Catalog No. A12922 DYRK inhibitorID-8 is a DYRK inhibitor. ID 8 also stimulates proliferation at a steady rate (observed in serum-free media supplemented with 10 μM over a 30 day period). Learn More -
NU 6102
Catalog No. A12438 CDK inhibitorNU6102 is selective for CDK1 and CDK2 compared to CDK4/D1 (IC50=1.6 μM), DYRK1A (IC50=0.9 μM), PDK1 (IC50=0.8 μM) and ROCKII (IC50=0.6 μM). Learn More