Search by product name, CAS, target or catalog number. Press Down Arrow to reach product suggestions, Tab to move between links, and Escape to close suggestions.
gp120/CD4 inhibitors block binding between the HIV envelope glycoprotein gp120 and the CD4 receptor on host cells. Human immunodeficiency virus (HIV) enters T cells when gp120 binds CD4 and then a co-receptor, which triggers membrane fusion. Attachment inhibitors bind gp120 and hold it in a shape that cannot engage CD4, while other compounds target CD4 or mimic its binding site. Compounds in this category are used in laboratory studies of viral entry and envelope protein structure.
DS-003 is a novel gp120 binder that serves as an analogue of BMS-378806. This compound exhibits potent and broad anti-HIV-1 activity, making it a valuable tool for research on HIV-1 infection and potential therapeutic strategies. Its ability to target gp120 facilitates insights into viral entry mechanisms, contributing to the development of effective antiviral agents.
Out of stock
All 3 sizes