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CD Markers

CD markers are cell-surface proteins used to define and distinguish immune cell populations. Each cluster of differentiation (CD) number names one defined surface molecule, and many of these molecules also have enzymatic or signaling functions. The compounds listed here act on such molecules rather than serving as antibodies or stains. PSB-12379 and AB-680 inhibit ecto-5'-nucleotidase (CD73), which converts adenosine monophosphate (AMP) to adenosine in the extracellular space. CD38 inhibitor 1 acts on the nicotinamide adenine dinucleotide (NAD+) glycohydrolase CD38. YYA-021 and BMS-806 interfere with binding of the human immunodeficiency virus (HIV) envelope glycoprotein gp120 to CD4, while AX-024 affects T cell receptor signaling. CD73 and gp120/CD4 also exist as separate sibling categories in the same immunology section.

4 Items

  • CD22 ligand-1
    Cat. No.
    A64164
    CAS No.
    2493080-27-4

    CD22 ligand-1

    CD22 ligand-1 is a potent and selective ligand for CD22, exhibiting a binding affinity (KD) of 0.335 µM for human CD22 and 30.7 µM for myelin-associated glycoprotein (MAG). This compound facilitates the investigation of CD22-mediated signaling pathways and holds potential for advancing research in B-cell related diseases, including autoimmune disorders and lymphomas. Its high specificity for CD22 makes it a valuable tool for understanding the role of this receptor in immunological responses.

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  • 1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine
    Cat. No.
    A65484
    CAS No.
    89947-80-8

    1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine

    1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine is a glycerophosphorylcholine that targets scavenger receptor class B, specifically CD36. This compound accumulates at sites of oxidative stress in vivo and is implicated in the molecular mechanisms of tumor apoptosis. Its interaction with oxidized phospholipids (oxPLs) suggests potential applications in cancer research and studies related to oxidative stress and inflammation.

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  • KDdiA-PC
    Cat. No.
    A65685
    CAS No.
    439904-34-4

    KDdiA-PC

    KDdiA-PC is a highly potent ligand for CD36, primarily targeting the receptor that mediates the cellular response to oxidized low-density lipoprotein (oxLDL). Its significant biological activity facilitates studies on lipid metabolism, inflammation, and atherosclerosis. KDdiA-PC is valuable for researchers investigating the role of CD36 in various physiological and pathological processes.

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    0.5 mg
    $140.00
    1 mg
    $270.00
    All 4 sizes
  • EP 80317
    Cat. No.
    B18678
    CAS No.
    268545-47-7

    EP 80317

    EP 80317 is a selective ligand for CD36. This compound exhibits cardioprotective effects against damage and dysfunction caused by myocardial ischemia and reperfusion, while also temporarily reducing peripheral lipolysis. EP 80317 is valuable in the investigation of cardiovascular disease mechanisms and potential therapeutic interventions.

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