Biochemical Assay Reagents

Cat. No.

A21224

CAS No.

85-32-5

5'-Guanylic acid

Synonyms: 5'-GMP; 5'-guanosine monophosphate

5'-Guanylic acid is a purine nucleotide that serves as a crucial regulator in energy metabolism, signal transduction, and gene expression. It influences the expression of genes associated with fatty acid metabolism and acts as a weak agonist for ionotropic glutamate receptors (iGluR), thereby modulating glutamatergic activity and exhibiting neuroprotective properties. However, at elevated concentrations, 5'-Guanylic acid can induce neuronal cell death. This reagent is valuable for research in metabolic regulation and neurobiology.

Cat. No.

A35842

CAS No.

1217471-69-6

(2S)-OMPT triethylamine, in ethanol:chloroform (1:1), 98%

(2S)-OMPT triethylamine, in ethanol:chloroform (1:1), 98% is a selective agonist for the LPA3 G-protein-coupled receptor. This compound triggers downstream signaling events by activating calcium ion influx and promoting IL-6 release in cancer cells. Additionally, it has been shown to activate MAPK and Akt signaling pathways, making it valuable for research applications focused on ovarian cancer.

Cat. No.

A47943

CAS No.

7601-54-9

Trisodium phosphate

Trisodium phosphate is a food additive that acts as a buffering agent and stabilizer. It influences the growth parameters of Listeria monocytogenes, specifically affecting the lag phase and maximum growth rate. Additionally, Trisodium phosphate enhances the sensitivity of Gram-negative bacteria to antimicrobial agents such as Lysozyme and Nisin, making it valuable for research in food safety and microbiology.

Cat. No.

A57970

CAS No.

81319-59-7

7-Methyladenosine perchlorate

7-Methyladenosine perchlorate is a synthetic analog of adenosine that acts as an agonist at adenosine receptors. This compound effectively modulates cellular signaling pathways, making it a valuable reagent for investigating adenosine-related biological processes. Additionally, 7-Methyladenosine perchlorate holds potential as a tool in compound development, particularly as an inhibitor for biochemical assays.

Cat. No.

A59173

CAS No.

220556-69-4

ACEA

Synonyms: Arachidonyl-2-chloroethylamide

ACEA (arachidonyl-2'-chloroacetamide) is a synthetic compound that acts as an agonist of the cannabinoid receptor CB1. It modulates the endocannabinoid system, influencing physiological processes including appetite regulation, pain perception, mood, and memory. This biochemical assay reagent is essential for research exploring the pharmacological effects and therapeutic potential of cannabinoid signaling.

Cat. No.

A67077

CAS No.

5550-12-9

5'-Guanylic acid disodium salt

Synonyms: 5'-GMP disodium salt; 5'-guanosine monophosphate disodium salt

5'-Guanylic acid disodium salt is a purine nucleotide that primarily functions as a signaling molecule in various physiological processes, including energy metabolism and gene expression regulation. It plays a crucial role in modulating genes associated with fatty acid metabolism. Additionally, this compound acts as a weak agonist for ionotropic glutamate receptors (iGluR), thereby reducing glutamatergic activity and exerting neuroprotective effects. However, at elevated concentrations, 5'-Guanylic acid disodium salt can induce neuronal cell death, making it valuable for studies on neuroprotection and excitotoxicity.

Cat. No.

A71356

CAS No.

14292-27-4

3-Hydroxyoctanoic acid

3-Hydroxyoctanoic acid acts as an agonist for the orphan receptor GPR109B, promoting an increase in intracellular calcium levels in human neutrophils expressing this receptor. This hydroxylated fatty acid, which occurs in the lipopolysaccharides of Pseudomonas aeruginosa and in poly(3-hydroxyalkanoate) produced by Pseudomonas oleophores, plays a role in metabolic studies. Research indicates that 3-hydroxyoctanoic acid interferes with lipolysis in human adipocytes and demonstrates significant changes in plasma levels under various dietary conditions, making it a valuable reagent for biochemical assays focused on metabolic regulation and related disorders.

Cat. No.

A87300

CAS No.

2295-31-0

2,4-Thiazolidinedione

2,4-Thiazolidinedione is a biochemical reagent primarily known for its role as a PPAR gamma agonist, targeting peroxisome proliferator-activated receptors. This compound exhibits significant biological activity in modulating insulin sensitivity and glucose metabolism, making it useful in research focused on diabetes, obesity, and metabolic disorders. Its applications extend to studies investigating cellular processes and the effects of thiazolidinediones in various biological systems.

Cat. No.

A88027

CAS No.

68915-31-1

Sodium polyphosphate, crystal,+200 mesh, 96%

Sodium polyphosphate is a water-soluble inorganic stabilizer that functions as a surfactant and metal ion chelator. With a purity of 96% and a particle size of +200 mesh, this compound demonstrates key biological activity in biochemical assays. It is commonly utilized in various applications, including food, cosmetics, and industrial products, to enhance texture and stability while mitigating metal ion-induced degradation, thereby prolonging shelf life.

Cat. No.

A88993

CAS No.

868843-84-9

BMVC4

BMVC4 is a G-quadruplex (G4) stabilizer specifically targeting the human telomeric sequence d[AG3(T2AG3)3]. This compound exhibits enhanced suitability as a core molecule for G4 stabilizers and demonstrates significant potential for anticancer research applications. Using circular dichroism (CD) spectroscopy, BMVC4 shows improved stability compared to other derivatives in the presence of trivalent cations. Additionally, a rapid screening method utilizing Cu2+-induced G4 unfolding can be employed to identify superior G4 stabilizers, emphasizing BMVC4's role as a promising candidate for further study in therapeutic settings.

Cat. No.

A89274

CAS No.

22432-79-7

Stearyl arachidate

Synonyms: Arachidic acid stearyl ester

Stearyl arachidate is a biochemical assay reagent that serves as a surfactant and stabilizer in various biological applications. It exhibits properties conducive to enhancing solubility and bioavailability of hydrophobic compounds, making it valuable for studies in drug formulation and delivery. This compound is particularly useful in research focused on lipid interactions and membrane biophysics.

Cat. No.

A90590

CAS No.

120225-64-1

CGS 21680 sodium

CGS 21680 sodium is an adenosine A2A receptor agonist that selectively activates the A2A receptor, influencing various signaling pathways. This compound exhibits biological activities such as modulation of neurotransmission and anti-inflammatory effects, making it useful in research involving neurological and cardiovascular studies. It is commonly employed in biochemical assays to explore the roles of adenosine receptors in cellular processes and their potential therapeutic applications.

Cat. No.

A90699

CAS No.

1667762-62-0

Recanaclotide

Synonyms: IW-9179

Recanaclotide is a biochemical reagent that acts as a selective guanylate cyclase-C receptor agonist. It has been shown to modulate gastrointestinal motility and fluid secretion, making it relevant for research on gastroparesis, functional dyspepsia, and various gastrointestinal disorders. This compound provides valuable insights into gut physiology and potential therapeutic interventions.

Cat. No.

A91358

CAS No.

128446-32-2

β-Cyclodextrin, 2-hydroxyethyl ethers

β-Cyclodextrin, 2-hydroxyethyl ethers functions as a biochemical reagent that primarily acts as a solubilizing agent and stabilizer for various compounds. Its unique structure enhances the solubility of hydrophobic molecules, making it valuable in pharmaceutical and biochemical research applications. It is often used in drug delivery systems, formulation of nanoparticles, and studies involving inclusion complexes to improve the bioavailability of therapeutic agents.

Cat. No.

A92502

CAS No.

1465-16-3

1-Methylpsilocin

1-Methylpsilocin is a biochemical assay reagent that primarily acts as a selective agonist of serotonin receptors, particularly the 5-HT2A subtype. It exhibits notable hallucinogenic properties and influences various neural pathways associated with mood and perception. This compound is utilized in research applications focused on neuropharmacology, psychopharmacology, and studies investigating the mechanisms of psychedelic compounds.

Cat. No.

A92970

CAS No.

39491-53-7

5'-Ethylcarboxamido-2',3'-isopropylidene adenosine

5'-Ethylcarboxamido-2',3'-isopropylidene adenosine is a selective agonist targeting A2B adenosine receptors. This compound enhances A2B receptor activity, making it valuable for investigating the physiological roles of adenosine signaling in various biological processes. It serves as a pertinent tool in biochemical assays and research applications aimed at understanding adenosine's effects and its potential as a therapeutic target in drug development.

Cat. No.

A94933

CAS No.

38339-23-0

Clenhexerol

Clenhexerol is a selective beta-adrenergic agonist that primarily targets beta-2 adrenergic receptors. This compound exhibits biological activity by stimulating smooth muscle relaxation and inducing bronchodilation. It is commonly used as a biochemical assay reagent control in research focused on respiratory diseases, pharmacological studies, and the exploration of adrenergic signaling pathways.

Cat. No.

B21310

CAS No.

84-21-9

Adenosine 3′-monophosphate

Synonyms: 3′-AMP

Adenosine 3'-monophosphate (3'-AMP) is a nucleotide that serves as a potent agonist for cyclic AMP production. It enhances cyclic AMP levels in a concentration-dependent manner in NG108-15 cells, making it valuable for studying cellular signaling pathways. Additionally, 3'-AMP is utilized in clinical laboratory settings to assess acid phosphatase activity in human serum, aiding in the diagnosis of conditions such as prostate cancer, metastatic breast cancer, and Gaucher’s disease. Furthermore, it exhibits the ability to inhibit the proliferation of human aortic and coronary vascular smooth muscle cells through the activation of A2B receptors.

Cat. No.

B21361

CAS No.

54-77-3

1,1-Dimethyl-4-phenylpiperazinium iodide

Synonyms: 1,1-Dimethyl-4-phenylpiperazin-1-ium iodide

1,1-Dimethyl-4-phenylpiperazinium iodide is a biochemical assay reagent that functions as a cholinergic agonist, primarily targeting nicotinic and muscarinic acetylcholine receptors. This compound is utilized in various research applications to study neurotransmission, muscle contraction, and signal transduction pathways. Its ability to evoke physiological responses makes it valuable in pharmacological and neurobiological studies.