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Oxytocin Receptor

Oxytocin receptor antagonists and agonists act on the receptor for the neurohypophysial hormone oxytocin. The human oxytocin receptor was cloned and characterized in 1992 as a member of the G protein-coupled receptor superfamily. In peripheral tissues it mediates uterine contraction and milk ejection, while central oxytocin signaling is studied in social behavior. Atosiban is a peptide antagonist that also binds the vasopressin V1a receptor. Retosiban, epelsiban and L-368,899 hydrochloride are nonpeptide oxytocin receptor antagonists. Carbetocin is a long-acting peptide agonist, and oxytocin itself serves as the reference ligand in binding and functional assays.

1 Item

  • Kalata B7
    Cat. No.
    A62797
    CAS No.
    339532-29-5

    Kalata B7

    Kalata B7 is a cyclotide that selectively targets the oxytocin and vasopressin V1a receptors as a partial agonist. Its unique cyclic structure enables it to penetrate cell membranes effectively, facilitating its biological activity. This reagent is primarily utilized in research applications focusing on the modulation of receptor signaling pathways associated with social behavior, stress responses, and cardiovascular functions.

    In stock View Details
    5 mg
    $350.00
    10 mg
    $650.00
    All 3 sizes

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