Prostanoid Receptors

Cat. No.

A20101

CAS No.

945721-87-9

GSK726701A

GSK726701A is a novel prostaglandin E2 receptor 4 (EP4) partial agonist with a pEC50 of 7.4.

Cat. No.

A63128

CAS No.

325780-75-4

CCI17464

CCI17464 is a selective, orally active EP4 partial agonist with a pKi of 7.1. This compound demonstrates significant biological activity in the modulation of inflammatory responses and has been effectively utilized in the Freund's complete adjuvant (FCA) acute rat inflammatory pain model. CCI17464 shows promise in the complete reversal of allergic reactions, making it a valuable tool for research in inflammation and allergic responses.

Cat. No.

A63335

CAS No.

191919-01-4

8-iso-15-keto Prostaglandin F2α

Synonyms: 8-iso-15-keto PGF2α

8-iso-15-keto Prostaglandin F2α is a partial agonist targeting the Thromboxane receptor (TP). It demonstrates notable vasoconstrictive activity with a pD2 value of 5.8. Additionally, at elevated concentrations, this compound can induce mild relaxation effects in rat aorta rings, making it relevant for studies in vascular biology and related research applications.

Cat. No.

A63338

CAS No.

170291-06-2

AL-6598

AL-6598 is a partial agonist of the prostaglandin DP and EP receptors. This compound is known to effectively reduce intraocular pressure, making it valuable for research related to glaucoma and ocular health. Investigations utilizing AL-6598 can provide insights into the mechanisms of intraocular pressure regulation and potential therapeutic strategies for glaucoma management.

Cat. No.

A63406

CAS No.

87440-45-7

Taprostene sodium

Synonyms: CG 4203 sodium

Taprostene sodium is a partial agonist of prostanoid IP receptors, demonstrating a unique mechanism of action in modulating vascular and cardiac functions. This compound exhibits significant cardioprotective properties and can interact additively with Prostaglandin E2 (PGE2) and selective EP2 agonists. Taprostene sodium serves as a valuable tool in cardiovascular research, particularly in studies focused on vascular biology and cardiac health.