Adenosine Receptors

Cat. No.

A57898

CAS No.

618380-90-8

GS-9667

Synonyms: CVT 3619

GS-9667 is a selective partial agonist of the A1 adenosine receptor (A1AdoR). This N6-5'-substituted adenosine analog effectively reduces cyclic AMP levels and inhibits the release of nonesterified fatty acids from epididymal adipocytes, demonstrating IC50 values of 6 nM and 44 nM, respectively. Its ability to inhibit lipolysis suggests potential applications in research related to Type 2 diabetes (T2DM) and dyslipidemia by lowering free fatty acids (FFA).

Cat. No.

A57917

CAS No.

333962-91-7

LUF5834

LUF5834 is a selective partial agonist of the A2B adenosine receptor (A2BR), with an EC50 of 12 nM. Additionally, LUF5834 exhibits partial agonistic activity at the A1 and A2A adenosine receptors, with Ki values of 2.6 nM and 28 nM, respectively. This compound is valuable in studies investigating adenosine signaling pathways, receptor pharmacology, and potential therapeutic applications related to the modulation of adenosine receptor activity.

Cat. No.

A58047

CAS No.

342419-10-7

CVT-2759 analog

CVT-2759 analog is a partial agonist of the A1 adenosine receptor, exhibiting a Ki value of 167 nM. This compound is valuable for research into cardiac arrhythmias, providing insights into the modulation of adenosine receptor signaling and its implications in cardiac health. Its specificity for the A1 receptor makes it a suitable tool for studying the physiological effects of adenosine in cardiac tissue.