Other Inhibitors

Cat. No.

A10868

CAS No.

18883-66-4

Streptozotocin

Synonyms: Streptozocin; Zanosar; STZ

Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro.

Cat. No.

A12895

CAS No.

1009816-48-1

Thiamet G

Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal-hexosaminidase.

Cat. No.

A15180

CAS No.

155294-62-5

NB-598 Maleate

NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway.

Cat. No.

A14406

CAS No.

530141-72-1

T-5224

T-5224 is a selective inhibitor of c-Fos/activator protein-1.

Cat. No.

A15248

CAS No.

894787-30-5

ST 2825

ST 2825 is a MyD88 pharmacologic inhibitor.

Cat. No.

A11613

CAS No.

139110-80-8

Zanamivir

Synonyms: Relenza

Zanamivir is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus.

Cat. No.

A13719

CAS No.

81846-19-7

Treprostinil

Treprostinil is a stable analog of prostacyclin that is used clinically for the treatment of PPH.

Cat. No.

A10015

CAS No.

90-33-5

4-Methylumbelliferone (4-MU)

Synonyms: 4-MU

4-Methylumbelliferone is a selective inhibitor of Hyaluronan (HA) synthesis which is thought to function as an inhibitor via the depletion of UDP-glucuronic acid, the common substrate for HA synthesis.

Cat. No.

A10031

CAS No.

103-84-4

Acetanilide

Synonyms: Acetanil; Acetamidobenzene; Acetylaniline; NSC 7636; acetanilid

Acetanilide is used as an inhibitor in hydrogen peroxide and is used to stabilize cellulose ester varnishes.

Cat. No.

A10034

CAS No.

114607-46-4

Acitazanolast

Synonyms: WP-871; Zepelin

Acitazanolast is an active metabolite of tazanolast and anti-allergic drug.

Cat. No.

A10144

CAS No.

33570-04-6

Bilobalide

Bilobalide, a biologically active terpenic trilactone (terpinoid), derived from geranylgeranyl pyrophosphate (GGPP) is an inducer of cytochrome P450 enzymes CYP3A1 and CYP1A2. May contain properties to stop apoptosis activation of the phosphatidylinositol 3-Kinase pathway in SH-SY5Y cells.

Cat. No.

A10409

CAS No.

13189-98-5

Fudosteine

Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor.

Cat. No.

A10738

CAS No.

5189-11-7

Pizotifen malate

Synonyms: Sandomigran; pizotyline

Pizotifen malate, a derivative of benzocycloheptathiophene, is a tricyclic compound found to be a potent inhibitor of SR-2 receptor activity.

Cat. No.

A10912

CAS No.

78628-80-5

Terbinafine hydrochloride

Synonyms: Zabel; Lamisil

Terbinafine HCl a member of the allylamine class of antifungals, has been found to be a specific inhibitor of ergosterol synthesis via squalene epoxidase inhibition.

Cat. No.

A11228

CAS No.

944328-88-5

QS 11

QS-11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor.

Cat. No.

A11312

CAS No.

24853-80-3

Pipofezine (Azaphen)

Synonyms: Azafen; Pipofezin hydrochloride; Pipofezine hydrochloride; Azaphenonxazine; Azaphen

Azafen is a tricyclic antidepressant.It acts as a potent inhibitor of the reuptake of serotonin.

Cat. No.

A11366

CAS No.

915365-57-0

Cot inhibitor-1

Cot inhibitor-1 is a COT/Tpl2 inhibitor.

Cat. No.

A11370

CAS No.

223663-32-9

Collagen proline hydroxylase inhibitor-1

Collagen proline hydroxylase inhibitor-1 is an antifibroproliferative agents.

Cat. No.

A11475

CAS No.

461054-93-3

Ko-143

Synonyms: Ko 143,Ko143

Ko 143 is potent and selective inhibitor of breast cancer resistance protein multidrug transporter (BCRP) with an EC90 value of 26 nM.

Cat. No.

A11660

CAS No.

123447-62-1

Prulifloxacin (Pruvel)

Synonyms: Pruvel

Prulifloxacin is an older synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class. Like other fluoroquinolones, Prulifloxacin prevents bacterial DNA replication, transcription, repair and recombination through inhibition of bacterial DNA gyrase.

Cat. No.

A11821

CAS No.

130641-38-2

Bindarit

Bindarit is an anti-inflammatory small molecule that modulates the NFκB pathway.

Cat. No.

A12187

CAS No.

883003-62-1

FUBP1-CIN-1

FUBP1-CIN-1 is a potent FUSE binding protein 1 (FUBP1) inhibitor which interferes with the binding of FUBP1 to its single stranded target DNA FUSE sequence , with an IC50 value of 11.0 μM.

Cat. No.

A12247

CAS No.

312271-03-7

M2I-1

M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC).

Cat. No.

A12296

CAS No.

245075-84-7

LR-90

LR-90 is an advanced glycation end product (AGE) inhibitor, inhibits inflammatory responses in human monocytes. LR-90 is also used in the research of diabetic animal model.

Cat. No.

A12336

CAS No.

1141777-14-1

Emixustat

Synonyms: ACU-4429

Emixustat, a novel visual cycle modulator, is an inhibitor of the visual cycle isomerase with an IC50 value of 4.4 nM in vitro.