Impurities & Reference Standards

Cat. No.

B10202

CAS No.

39108-34-4

1H,1H,2H,2H-Perfluorodecanesulfonic acid

1H,1H,2H,2H-Perfluorodecanesulfonic acid is a polyfluoroalkyl substance (PFAS) precursor that serves as a chemical building block in the synthesis of various fluorinated compounds. Its primary mechanism involves the formation of fluoroalkyl substances that exhibit properties such as increased hydrophobicity and chemical stability. This reagent is primarily used in environmental research and toxicology studies to investigate the behavior and fate of PFAS in ecosystems and human health.

Cat. No.

B10226

CAS No.

527-53-7

1,2,3,5-Tetramethylbenzene

Synonyms: Isodurene

1,2,3,5-Tetramethylbenzene, also known as Isodurene, is an aromatic hydrocarbon isomer of tetramethylbenzene. This compound serves a crucial role in industrial organic solvents and is utilized in the organic synthesis of plastics and resins. Additionally, 1,2,3,5-Tetramethylbenzene is noted for its potential neurotoxic effects, acute oral toxicity, and mild skin irritation, making it relevant for safety assessments in chemical research and development.

Cat. No.

B10453

CAS No.

28360-89-6

(E)-Crotylbarbital

(E)-Crotylbarbital is an isomer of the barbiturate derivative Crotylbarbital, targeting central nervous system pathways. This compound exhibits potential sedative and hypnotic properties, making it relevant for research focused on sleep disorders such as insomnia. Its unique structure allows for investigations into the mechanisms of barbiturates and their effects on neuronal activity.

Cat. No.

B10553

CAS No.

16995-35-0

1,1,1,3-Tetrachloroacetone

1,1,1,3-Tetrachloroacetone is a halogenated compound that serves as a disinfection byproduct (DBP) primarily formed in the presence of chlorine or chloramine and elevated bromide levels. Its role in chemical processes highlights its significance in the study of water disinfection efficacy and safety. Researchers utilize this reagent to explore the formation mechanisms and toxicity profiles of DBPs, aiding in the assessment of water treatment methods and public health implications.

Cat. No.

B10814

CAS No.

1858282-76-4

(S)-Subasumstat

Synonyms: (S)-TAK-981

(S)-Subasumstat is the isomer of Subasumstat (TAK-981), a selective inhibitor of the SUMOylation enzymatic cascade. This compound exhibits potential immune-activating and antineoplastic activities, making it a valuable tool in cancer research. Its ability to modulate SUMOylation pathways opens new avenues for investigating therapies targeting malignant tumors and immune responses.

Cat. No.

B10815

CAS No.

20016-85-7

(R)-2-Hydroxybutanoic acid

Synonyms: (R)-α-Hydroxybutyric acid

(R)-2-Hydroxybutanoic acid is an isomer of 2-Hydroxybutyric acid, serving as a valuable experimental control in research. This compound is a key intermediate in the conversion of 2-Aminobutyric acid and plays a role in metabolic studies. Its utilization is significant in investigations related to metabolic pathways and biochemical analysis in various biological contexts.

Cat. No.

B10820

CAS No.

4254-14-2

(R)-(-)-1,2-Propanediol

(R)-(-)-1,2-Propanediol is the (R)-isomer of 1,2-Propanediol, a key compound utilized in various chemical processes. Known for its role as a versatile solvent and humectant, this reagent is significant in the production of antifreeze formulations, cosmetics, and pharmaceuticals. Its stereochemistry contributes to specific biological activities, making it valuable in biochemical research and product development.

Cat. No.

B10825

CAS No.

40222-77-3

2-Hydroxymethyl-5-hydroxypyridine

2-Hydroxymethyl-5-hydroxypyridine acts as a drug isomer with potential pharmaceutical applications. This compound exhibits various biological activities, making it relevant for research in medicinal chemistry and drug development. Its derivation from the seeds of S. lychnophora underscores its natural origin, which can be of interest in studies focusing on phytochemicals and their therapeutic potential.

Cat. No.

B10839

CAS No.

259200-31-2

(2S,3R)-Brassinazole

(2S,3R)-Brassinazole is a selective inhibitor of brassinosteroid (BR) biosynthesis, primarily targeting the oxidative conversion of 6-oxo-campestanol to teasterone. This enantiomer exhibits significant biological activity, potentially representing the most effective form of brassinazole in regulating plant growth and development. Research applications include investigations into hormone signaling pathways and the elucidation of brassinosteroid functions in various biological processes.

Cat. No.

B10845

CAS No.

593-40-8

Petroselaidic acid

Synonyms: trans-Petroselinic acid; trans-6-Octadecenoic acid

Petroselaidic acid is a trans fatty acid and the trans isomer of petroselinic acid. It exhibits potential biological activity related to fatty acid metabolism and is relevant in studies of trans fatty acid effects on human health. Key research applications include investigations into the role of trans fatty acids in lipid metabolism and their impact on nutrition and cardiovascular health. This compound is naturally found in dairy products such as cow's milk and goat's milk, providing insights into its dietary significance.

Cat. No.

B10846

CAS No.

2517682-14-1

(R)-NVS-ZP7-4

(R)-NVS-ZP7-4 is a selective inhibitor of the zinc transporter SLC39A7 (ZIP7) and represents the R-isomer of NVS-ZP7-4. This compound is a valuable tool for investigating the modulation of endoplasmic reticulum (ER) zinc levels and elucidating the role of ZIP7 in the Notch signaling pathway. Its biological activity allows for advanced research into cellular zinc homeostasis and its implications in various physiological processes.

Cat. No.

B10847

CAS No.

2988224-39-9

(R)-ONO-2952

(R)-ONO-2952 is a highly selective enantiomer of ONO-2952, acting as a potent antagonist of the translocator protein (TSPO) with inhibition constants (Kis) ranging from 0.33 to 9.30 nM for both rat and human TSPO. This compound exhibits a notable selectivity for TSPO over other receptors, transporters, ion channels, and enzymes. Its significant biological activity makes it a valuable tool for research applications focused on neuroinflammation, neuroprotection, and various TSPO-related pathways in cellular and molecular studies.

Cat. No.

B10848

CAS No.

2328064-33-9

(rac)-Lomedeucitinib

Synonyms: (rac)-BMS-986322

(rac)-Lomedeucitinib is a racemic mixture that functions primarily as a selective inhibitor of the tyrosine protein kinase 2 (TYK2). This compound exhibits potent anti-inflammatory effects, specifically inhibiting interferon-alpha production with an IC50 value of 0.047 μM, thereby modulating immune responses. Its biological activity makes it suitable for research applications related to plaque psoriasis and pruritus, facilitating investigations into therapeutic interventions for these conditions.

Cat. No.

B10853

CAS No.

2003228-82-6

(S)-ARI-1

(S)-ARI-1 is the S-enantiomer of ARI-1, a selective inhibitor of the receptor tyrosine kinase ROR1. This compound is known to induce apoptosis and shows significant potential in the investigation of non-small cell lung cancer (NSCLC). Its ability to modulate ROR1 activity makes it a valuable tool for studying cancer cell signaling and therapeutic strategies in oncology research.

Cat. No.

B10858

CAS No.

1428652-15-6

(Rac)-Baxdrostat

Synonyms: (Rac)-CIN-107

(Rac)-Baxdrostat is an isomer of Baxdrostat, primarily acting as an aldosterone synthase inhibitor. This compound serves as an experimental control in research studies aimed at understanding aldosterone regulation and its implications in various physiological and pathological conditions. Its biological activity makes it a valuable tool for exploring the effects of aldosterone modulation in both endocrine and cardiovascular research applications.

Cat. No.

B10864

CAS No.

64234-00-0

ent-DMPC

ent-DMPC is an enantiomer of Colfosceril miristate (DMPC) and serves as a phospholipid model in membrane studies. It primarily targets membrane dynamics and interactions, contributing to research in surfactant functions and pulmonary surfactant replacement therapies. Its unique properties facilitate the exploration of lipid bilayer behavior and drug delivery systems, making it a valuable reagent in biochemical and pharmaceutical research.

Cat. No.

B10868

CAS No.

96862-25-8

(E)-1α,25-Dihydroxyprevitamin D3

(E)-1α,25-Dihydroxyprevitamin D3 is a drug isomer and an analog of 1α,25(OH)2D3, exhibiting a similar biological activity. This compound has been shown to effectively modulate calcium homeostasis and influence bone metabolism, making it relevant for research in osteoporosis and other bone-related disorders. Its unique structure allows for exploration of vitamin D receptor signaling pathways, contributing to the understanding of various diseases associated with vitamin D deficiency.

Cat. No.

B10871

CAS No.

1037624-76-2

(R)-Bemcentinib

Synonyms: (R)-R428; (R)-BGB324

(R)-Bemcentinib, the R-isomer of Bemcentinib (R428), is a selective inhibitor of the Axl receptor tyrosine kinase, exhibiting an IC50 of 14 nM. This compound has demonstrated significant potential in inhibiting tumor metastasis and extending survival in preclinical models of metastatic breast cancer. Its application in cancer research underscores its importance in studying targeted therapies that disrupt Axl signaling pathways.

Cat. No.

B10872

CAS No.

116198-40-4

1,2-Dimyristoyl-3-eicosapentaenoyl-rac-glycerol

Synonyms: MME; 1,2-Myristin-3-eicosapentaenoin; 14:0/14:0/20:5-TG

1,2-Dimyristoyl-3-eicosapentaenoyl-rac-glycerol (MME) is a triglyceride isomer that serves as a model for studying lipid compositions in algal species. This compound exhibits variability in its isomer ratio in response to changes in culture temperature, making it valuable for investigating lipid metabolism and adaptation mechanisms. MME can be utilized in research focused on algal biotechnology, nutritional bioengineering, and the development of functional foods.

Cat. No.

B10876

CAS No.

17515-36-5

Tauroursocholic acid sodium

Synonyms: TUCA sodium

Tauroursocholic acid sodium is a taurine-conjugated bile acid and the 7β-hydroxy epimer of taurocholic acid. It plays a significant role in biliary tract cancer, where its elevated levels can disrupt the balance of bile acids, leading to cellular toxicity and promoting carcinogenesis through oxidative DNA damage. This compound is valuable for research applications focused on the mechanisms of biliary tract cancer development and the effects of bile acid dysregulation.

Cat. No.

B10877

CAS No.

85026-51-3

15(R)-Iloprost

Synonyms: 15(R)-Ciloprost; 15(R)-ZK 36374

15(R)-Iloprost is the inverted C-15 epimer of iloprost, primarily targeting prostacyclin receptors. This compound exhibits potent vasodilatory effects and is utilized in research related to cardiovascular function and pulmonary hypertension. Its unique structural properties make it a valuable tool for studying the physiological and pharmacological roles of prostacyclin analogs in various biological settings.

Cat. No.

B10878

CAS No.

84366-67-6

ent-DOPC

ent-DOPC is a glycerol chirality isomer of 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC). This compound is predominantly utilized in lipid bilayer studies and membrane biophysics, helping to better understand membrane dynamics and properties. Its unique chirality allows researchers to investigate the role of phospholipid stereochemistry in biological membranes and cellular processes.

Cat. No.

B10879

CAS No.

3844-67-5

(S)-Allantoin

(S)-Allantoin is the S-isomer of Allantoin, which selectively binds to the active site of urate oxidase. This compound can be enzymatically converted to Allantoate through the action of allantoicase. In research applications, (S)-Allantoin serves as a nitrogen source in the model organism Arabidopsis thaliana, facilitating studies in plant biology and metabolism.

Cat. No.

B10880

CAS No.

3095569-90-4

(R)-ACE-OH

(R)-ACE-OH is the enantiomer of (S)-ACE-OH, serving as a critical tool in drug development. This compound is vital for studying the pharmacological effects of chiral drugs and their biological interactions. Its applications include the investigation of stereochemistry in drug efficacy and the exploration of its role as a pharmaceutical intermediate in synthetic organic chemistry.

Cat. No.

B10890

CAS No.

487-48-9

Salacetamide

Synonyms: N-Acetylsalicylamide

Salacetamide, the stable isomer of O-Acetylsalicylamide, specifically targets proteomic applications. This compound is utilized in proteomics research to study protein modifications and interactions, making it essential for understanding biological processes. Its unique chemical properties facilitate various experimental designs aimed at elucidating protein function and dynamics in complex biological systems.