Impurities & Reference Standards

Cat. No.

A73934

CAS No.

17427-21-3

4-Hydroxy hexenal

Synonyms: 4-HHE

4-Hydroxy hexenal (4-HHE) is a lipid peroxidation product formed through the oxidation of omega-3 fatty acids, particularly docosahexaenoic acid (DHA). It serves as a biomarker for oxidative stress and is relevant in studying the role of lipid peroxidation in various pathological conditions. 4-HHE is useful for research applications investigating cell signaling pathways, inflammation, and neurodegeneration associated with oxidative damage.

Cat. No.

A74118

CAS No.

2307465-23-0

(R)-2-Hydroxybutanoic acid sodium

Synonyms: (R)-α-Hydroxybutyric acid sodium

(R)-2-Hydroxybutanoic acid sodium is the R-isomer of 2-Hydroxybutyric acid, functioning as a useful experimental control in biochemical studies. This compound plays a crucial role in metabolic processes, being derived from 2-Aminobutyric acid via 2-oxobutyric acid as an intermediate. Its biological activity is relevant in research applications focused on metabolic regulation and neurological function.

Cat. No.

A74193

CAS No.

13039-62-8

D-Biopterin

D-Biopterin is an enantiomer of L-Biopterin, functioning as a cofactor for nitric oxide synthase (NOS). This compound plays a crucial role in the biosynthesis of nitric oxide, a signaling molecule involved in various physiological processes. D-Biopterin is utilized for research applications in neurobiology, cardiovascular studies, and investigations into metabolic disorders where NOS activity is implicated.

Cat. No.

A74488

CAS No.

544-70-7

9(Z),11(Z)-Octadecadienoic acid

9(Z),11(Z)-Octadecadienoic acid is a geometric isomer of linoleic acid that exhibits antitumor activity. This compound acts through mechanisms that may involve modulation of cellular signaling pathways. Its biological activity makes it a valuable reagent for cancer research and studies exploring the role of dietary fatty acids in tumorigenesis.

Cat. No.

A74563

CAS No.

74923-08-3

4-Amino-3-hydroxyphenylalanine

Synonyms: 4-AHP

4-Amino-3-hydroxyphenylalanine (4-AHP) is a photodegradation product of eumelanin. This compound is significant in studies focusing on melanomagenesis in skin tissue and the mechanisms underlying age-related macular degeneration. Its biological activity may provide insights into the role of melanin in various pathophysiological conditions.

Cat. No.

A74950

CAS No.

1191996-10-7

(S,S)-Sinogliatin

Synonyms: (S,S)-HMS-5552; (S,S)-RO-5305552

(S,S)-Sinogliatin is the (S,S)-enantiomer of the glucokinase activator Sinogliatin, specifically targeting glucokinase to enhance its activity. This compound demonstrates significant potential in the modulation of glucose metabolism, making it a valuable tool for research applications related to type 2 diabetes. Its use can aid in investigating the therapeutic mechanisms underlying glucose homeostasis and pancreatic function.

Cat. No.

A75485

CAS No.

2008-58-4

2,6-Dichlorobenzamide

2,6-Dichlorobenzamide is a degradation product of herbicides with strong water solubility, which facilitates its movement into groundwater systems. It serves as an important compound for environmental studies, specifically in assessing herbicide impacts and the fate of chemical contaminants in aquatic environments. This compound is useful for research applications related to soil and water contamination and the development of remediation techniques.

Cat. No.

A76234

CAS No.

66701-63-1

(S)-DSPC

Synonyms: (S)-1,2-Distearoyl-sn-glycero-3-PC; (S)-1,2-Distearoyl-sn-glycero-3-phosphorylcholine

(S)-DSPC is the (S)-enantiomer of 1,2-Distearoyl-sn-glycero-3-phosphocholine, serving as a phospholipid component in various biological membranes. It exhibits significant biological activity by contributing to membrane structure and fluidity, making it valuable for studies involving liposomes and drug delivery systems. This reagent is applicable in research areas such as cell biology, membrane biophysics, and the development of lipid-based formulations.

Cat. No.

A76560

CAS No.

1831135-56-8

ABC34

ABC34 is an inactive control compound of JJH260 that provides a reliable reference for experimental studies. It demonstrates no inhibitory effects on the fluorophosphonate reactivity or fatty acid esters of hydroxy fatty acid (FAHFA) hydrolysis activity of AIG1. While ABC34 does not interact with these targets, it can inhibit both ABHD6 and PPT122, making it useful for elucidating the specific roles of active compounds in biological assays.

Cat. No.

A76657

CAS No.

1428652-16-7

(S)-Baxdrostat

Synonyms: (S)-CIN-107

(S)-Baxdrostat is the S-enantiomer of Baxdrostat, an aldosterone synthase inhibitor. This compound exhibits significant biological activity in modulating aldosterone levels, making it relevant for research on hypertension and cardiovascular disorders. Its mechanistic action provides a valuable tool for investigating endocrine regulation and potential therapeutic interventions in related conditions.

Cat. No.

A77087

CAS No.

1914971-16-6

PHGDH-inactive

PHGDH-inactive is a non-active control designed to assess the specificity of experimental results involving PHGDH inhibitors such as NCT-502 and NCT-503. As a negative control, this reagent does not interact with the PHGDH enzyme, ensuring the reliability of data in studies aimed at understanding the role of PHGDH in metabolic pathways. Utilizing PHGDH-inactive aids in differentiating compound effects and validating experimental findings in biochemical research.

Cat. No.

A77249

CAS No.

3063345-48-9

(Rac)-LRK-4189

(Rac)-LRK-4189 is the racemic mixture of the selective PIP4K2C PROTAC degrader LRK-4189. This compound demonstrates potent biological activity with a DC50 of less than 500 nM for PIP4K2C in MOLT-4 cells, promoting antitumor effects by inducing intrinsic cell death and activating interferon signaling pathways. (Rac)-LRK-4189 is applicable in research focused on immune-mediated tumor cell killing, particularly in studies involving microsatellite stable (MSS) colorectal carcinoma.

Cat. No.

A77431

CAS No.

852547-30-9

PKR Inhibitor, negative control

PKR Inhibitor, negative control is an inactive structural analog of RNA-dependent protein kinase (PKR) inhibitor, serving as a reliable negative control in experimental settings. Although it does not exhibit inhibition of PKR activity, it has been shown to inhibit lipopolysaccharide-induced neuronal death, thereby demonstrating notable neuroprotective effects. This reagent is particularly useful for validating the specificity of PKR-targeted experiments and studying neuroprotection mechanisms.

Cat. No.

A78120

CAS No.

142796-24-5

2,3-Dehydrosilybin B

2,3-Dehydrosilybin B is an enantiomer derived from the oxidation of the natural flavonolignan silybin A. This compound exhibits notable antioxidant properties and has been shown to have hepatoprotective effects. Its application in research includes studies related to liver health, oxidative stress, and potential therapeutic interventions for liver diseases.

Cat. No.

A79720

CAS No.

145854-61-1

Mastoparan 17

Mastoparan 17 is a tetradecapeptide that serves as an inactive analogue of Mastoparan. Its structure allows for the study of peptide interactions and functional assays without stimulating typical biological responses. This compound is useful in research applications involving receptor binding, signal transduction pathways, and the development of pharmacological treatments targeting mast cell activation.

Cat. No.

A86918

CAS No.

2627-86-3

(S)-(-)-1-Phenylethanamine

Synonyms: S-(-)-α-Phenylethylamine; L-(-)-α-Methylbenzylamine

(S)-(-)-1-Phenylethanamine is the S-isomer of 1-Phenylethanamine, functioning as a versatile pharmaceutical intermediate. This compound plays a crucial role in the synthesis of various biologically active molecules, making it valuable for research applications in medicinal chemistry and drug development. Its chirality contributes to the specificity of interactions in biological systems, facilitating the exploration of structure-activity relationships.

Cat. No.

A86976

CAS No.

18741-85-0

(R)-[1,1'-Binaphthalene]-2,2'-diamine

Synonyms: R-(-)-2,2-Diamino-1,1-binaphthyl

(R)-[1,1'-Binaphthalene]-2,2'-diamine is the chiral isomer of (S)-[1,1'-Binaphthalene]-2,2'-diamine, serving as an essential experimental control in stereochemical studies. This compound plays a crucial role in research applications involving asymmetric synthesis and catalysis. As a versatile biochemical reagent, it is suited for life science investigations, helping to elucidate the behavior of chiral molecules in various biochemical contexts.

Cat. No.

A87086

CAS No.

71850-09-4

Diisohexyl phthalate

Diisohexyl phthalate functions as a dialkyl phthalate plasticizer, enhancing the flexibility and durability of polymer materials. Its primary application is in the modification of polyvinyl chloride (PVC) products. However, it is important to note that diisohexyl phthalate may interfere with chromatographic analyses of PVC samples, which could impact experimental results in chemical research.

Cat. No.

A87243

CAS No.

84852-53-9

Decabromodiphenyl ethane

Synonyms: DBDPE; 1,2-Bis(perbromophenyl)ethane

Decabromodiphenyl ethane (DBDPE) is a brominated flame retardant that primarily targets polymeric materials, providing thermal stability and reducing flammability. Research indicates that DBDPE may have neurotoxic, thyroid-disrupting, reproductive developmental, and hepatotoxic effects, as well as potential oxidative stress in various biological systems. This compound is widely studied in toxicology and environmental sciences to understand its impact on human health and ecosystems.

Cat. No.

A87279

CAS No.

13674-84-5

Tris(1-chloro-2-propyl) phosphate

Synonyms: Tris(1-chloropropan-2-yl) phosphate

Tris(1-chloro-2-propyl) phosphate functions primarily as a flame retardant, targeting the inhibition of flammability in various materials. This compound demonstrates effectiveness in reducing the risk of ignition and the spread of fire, making it valuable in materials science and safety applications. Its properties are particularly relevant in research involving fire-resistant formulations and the assessment of material safety in industrial settings.

Cat. No.

A87379

CAS No.

30334-69-1

Perfluorobutanesulfonamide

Synonyms: FBSA

Perfluorobutanesulfonamide (FBSA) is a per- and polyfluoroalkyl substance that primarily targets the PFAS class of compounds. It is commonly detected as a contaminant in wastewater, making it relevant for studies on environmental persistence and toxicological effects. FBSA is utilized in research to better understand the behavior and impacts of PFAS in ecological systems and human health.

Cat. No.

A87503

CAS No.

423-50-7

Perfluorohexylsulfonyl fluoride

Synonyms: Perfluorohexanesulphonyl fluoride

Perfluorohexylsulfonyl fluoride is a perfluoroalkyl compound recognized as a persistent organic pollutant under the 2022 Stockholm Convention. This reagent is primarily used in organic synthesis for the modification of pharmaceutical compounds, enhancing their stability and bioactivity. It serves valuable applications in studies related to environmental chemistry and the behavior of polyfluoroalkyl substances in biological systems.

Cat. No.

A87566

CAS No.

2750799-11-0

NHS-SS-Ac

NHS-SS-Ac is an amine-reactive compound that features a N-hydroxysuccinimidyl (NHS) ester moiety, facilitating the conjugation of biomolecules. It demonstrates high efficiency in covalently linking amine-containing molecules, making it an essential reagent for bioconjugation applications. This product is commonly used in the development of targeted therapeutics, protein labeling, and the preparation of antibody-drug conjugates.

Cat. No.

A87931

CAS No.

19894-97-4

(-)-Myrtenol

(-)-Myrtenol is the enantiomer of myrtenol, known for its role in modulating neurotransmitter activity. This compound exhibits anti-anxiety effects, making it a valuable tool in neuropharmacological research. Additionally, (-)-Myrtenol demonstrates protective characteristics for gastric cells, indicating potential applications in studies related to gastrointestinal health.

Cat. No.

A88589

CAS No.

38406-57-4

Pinolenic acid methyl ester

Pinolenic acid methyl ester is a methylated derivative of pinolenic acid, primarily utilized for the quantification and analysis of fatty acid profiles in biological samples. This compound serves as a useful analytical reagent in lipid biochemistry research, facilitating the examination of fatty acid metabolism and potential health benefits associated with pinolenic acid. Its application extends to studies focusing on nutritional biochemistry and dietary impacts on health.