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VEGFR



Items 1 to 25 of 37 total

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Catalog No. Product Name Product Information
A12027

(-)-Catechin gallate

(-)-Catechin gallate is an antioxidant constituent of green tea. At uM concentrations, inhibits VEGF-induced tyrosine phosphorylation. Learn More
A10049

Albendazole

Albendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations. Learn More
A11407

Apatinib (YN968D1)

Apatinib (YN968D1) is a tyrosine kinase inhibitor that selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2, also known as KDR) that inhibits VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. Learn More
A10103

Axitinib

Axitinib is a small molecule tyrosine kinase inhibitor,which inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT (CD117). Learn More
A10137

Bibf1120 (Vargatef)

BIBF1120 (Vargatef) is a novel triple angiokinase inhibitor that inhibits three growth factor receptors simultaneously: VEGFR, PDGF and FGFR. Learn More
A11263

BMS-690514

BMS-690514 is a potent and selective inhibitor of epidermal growth factor receptor (EGFR), HER2, and HER4, as well as the VEGF receptor kinases. Learn More
A10254

Brivanib (BMS-540215)

Brivanib (BMS-540215) is a VEGFR -2 inhibitor with an IC50 of 25 nM and Ki of 26 nM. Learn More
A10162

Brivanib alaninate (BMS-582664)

Brivanib alaninate (BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling. Learn More
A10185

Cediranib (AZD2171)

Cediranib (AZD2171) s a potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases. Learn More
A10204

Chloroxine

Chloroxine is an antibacterial drug useful for dandruff and seborrheic dermatitis. Learn More
A11772

CP-547632

CP-547632 is a novel, potent vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor Learn More
A10248

CYC116

Aurora kinase/VEGFR 2 inhibitor CYC116 inhibits Aurora kinases A and B and vascular endothelial growth factor receptor 2 (VEGFR2), resulting in disruption of the cell cycle, rapid cell death, and the inhibition of angiogenesis. Learn More
A11978

Delphinidin chloride

Delphinidin chloride is an anthocyanidin, a common plant pigment, found in pigmented fruits and vegetable. Learn More
A11396

E-7050 (Golvatinib)

E7050 (also known as golvatinib is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity. Learn More
A10340

E7080 (Lenvatinib)

E7080 is a multi-kinase inhibitor that inhibits both VEGFR2 and VEGFR3 kinases. Learn More
A10259

Imatinib (Gleevec)

Imatinib (Gleevec) is a number of tyrosine kinase enzymes specific inhibitor. Learn More
A10495

Kaempferol

Kaempferol is found to inhibit bovine aorta myosin light chain kinase with a Ki of 0.3-0.5 microM and also is found to inhibit VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway. Learn More
A10502

Ki8751

Ki8751 is a cell-permeable quinolyloxyphenyl-urea compound that acts as a Flk-1 (VEGFR-2)-selective inhibitior in both cell-based and cell-free assays. Learn More
A10504

KRN 633

KRN 633 is a cell-permeable, reversible, ATP-competitive VEGFR kinase inhibitor that inhibits PDGFR-α and c-Kit at higher concentrations only (IC50 = 0.97 μM and 4.33 μM, respectively) and inactive towards 17 other kinases (IC50 ≥ 10 μM). Learn More
A10025

Linifanib (ABT-869)

Linifanib (ABT-869) is a structurally novel, potent inhibitor of RTK, VEGF and PDGF with IC50 of 0.2, 2, 4, and 7 nM for human endothelial cells, PDGFR-β, KDR, and CSF-1R, respectively. Learn More
A11496

Motesanib (AMG706)

Motesanib (AMG706) is a multikinase inhibitor that selectively targets VEGF receptors, platelet-derived growth factor receptors (PDGFRs), and Kit receptors with IC?? values of 2 nM (VEGFR1), 3 nM (VEGFR2), 6 nM (VEGFR3), 84 nM (PDGFR), and 8 nM (Kit). Learn More
A10608

Motesanib Diphosphate (AMG-706)

Motesanib, also known as AMG-706, is an orally administered multikinase inhibitor that selectively targets VEGF receptors, platelet-derived growth factor receptors, and Kit receptors. Learn More
A10699

Pazopanib HCl (GW786034)

Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-a/β, and c-kit that blocks tumor growth and inhibits angiogenesis. Learn More
A13377

SAR131675

SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activities. Learn More
A13234

SKLB1002

SKLB1002 is a new potent VEGFR2 inhibitor, which could significantly inhibit HUVEC proliferation, migration, invasion, and tube formation. Learn More

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VEGFR

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