Telatinib (BAY 57-9352)

Name: Telatinib (BAY 57-9352)
Brand: Adooq Bioscience
SKU: A10903
Rating: 100 (268 reviews)

Catalog No.: A10903

VEGFR-2 inhibitor

Telatinib (BAY 57-9352) Chemical Structure

CAS NO. 332012-40-5

Telatinib (BAY 57-9352) is an orally available, small-molecule inhibitor of vascular endothelial growth factor receptors 2 and 3 (VEGFR-2/-3) and platelet-derived growth factor receptor β tyrosine kinases.

Availability: In stock

Package	Price	Qty
5 mg	Regular Price: $90.00 Special Price $72.00
10 mg	Regular Price: $160.00 Special Price $128.00
50 mg	Regular Price: $450.00 Special Price $360.00
100 mg	Regular Price: $750.00 Special Price $600.00
10mM * 1mL in DMSO	Regular Price: $133.00 Special Price $106.40
Custom Size	Get quote

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Biological Activity

Targets

c-Kit	VEGFR3	VEGFR2	PDGFRα
1 nM	4 nM	6 nM	15 nM

Solubility *

In vitro	DMSO	71 mg/mL (173.24 mM)
	Water	Insoluble
	Ethanol	1 mg/mL (2.44 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.4 mL	122.01 mL	244.02 mL
0.5 mM	4.88 mL	24.4 mL	48.8 mL
1 mM	2.44 mL	12.2 mL	24.4 mL
5 mM	0.49 mL	2.44 mL	4.88 mL

*The above data is based on the productmolecular weight 409.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A10903
Actions	Inhibitor
CAS No.	332012-40-5
Formula	C20H16ClN5O3
M. Wt	409.8
Purity	>98%
Synonyms	BAY57-9352
SMILES	CNC(=O)C1=NC=CC(=C1)COC2=NN=C(C3=C2OC=C3)NC4=CC=C(C=C4)Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.