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Publications citing Adooq Products
Chemical Information
| Catalog Num | A10903 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 409.8 |
| Formula | C20H16ClN5O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 332012-40-5 |
| Synonyms | BAY57-9352 |
| SMILES code | CNC(=O)C1=NC=CC(=C1)COC2=NN=C(C3=C2OC=C3)NC4=CC=C(C=C4)Cl |
| Chemical Name | 4-[[[4-[(4-Chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl]oxy]methyl]-N-methyl-2-pyridinecarboxamide |
Description |
Telatinib (BAY 57-9352) is an orally available, small-molecule inhibitor of vascular endothelial growth factor receptors 2 and 3 (VEGFR-2/-3) and platelet-derived growth factor receptor β tyrosine kinases. | ||||||||||
Targets |
|
||||||||||
| Solubility (25°C)* | In vitro | DMSO | 82 mg/mL (200.08 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 1 mg/mL (2.44 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.4 mL | 122.01 mL | 244.02mL |
| 0.5 mM | 4.88 mL | 24.4 mL | 48.8 mL |
| 1 mM | 2.44 mL | 12.2 mL | 24.4 mL |
| 5 mM | 0.49 mL | 2.44 mL | 4.88 mL |
*The above data is based on the productmolecular weight 409.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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