Biological Activity
ZM 323881 is a potent and selective inhibitor of the kinase activity of the human vascular endothelial growth factor receptor 2 (VEGFR2/KDR).
In vitro (25°C) | DMSO | 9 mg/mL (21.85 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 1% CMC Na | 19 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.28 mL | 121.4 mL | 242.8 mL |
0.5 mM | 4.86 mL | 24.28 mL | 48.56 mL |
1 mM | 2.43 mL | 12.14 mL | 24.28 mL |
5 mM | 0.49 mL | 2.43 mL | 4.86 mL |
*The above data is based on the productmolecular weight 411.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A11954 |
---|---|
Actions | Inhibitor |
CAS No. | 324077-30-7 |
Formula | C22H18FN3O2.HCl |
M. Wt | 411.86 |
Purity | >98% |
Synonyms | ZM323881 |
SMILES | CC1=CC(=C(C=C1O)NC2=NC=NC3=C2C=CC(=C3)OCC4=CC=CC=C4)F.Cl |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Datasheet
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
Regorafenib (BAY 73-4506)
Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf. Regorafenib (BAY 73-4506) is an ora…
Taxifolin
Taxifolin is found to bind at the ATP-binding site on VEGFR-2 kinase with large value of binding energy and act as type I competitive inhibi…
SU 5416 (Semaxinib)
SU 5416 is an inhibitor of vascular endothelial growth factor receptor (VEGFR) that also inhibits other tyrosine kinases KIT, MET, FLT3 and …
Tivozanib (AV-951)
Tivozanib (AV-951) is an oral VEGF receptor tyrosine kinase inhibitor that is designed to inhibit all three VEGF receptors.
E7080 (Lenvatinib)
E7080 is a multi-kinase inhibitor that inhibits both VEGFR2 and VEGFR3 kinases.
TG 100572
TG 100572 is VEGFR2 and Src kinase inhibitor.
XL647 (Tesevatinib)
XL647 is an orally bioavailable small-molecule RTK inhibitor that binds to and inhibits several tyrosine receptor kinases that play major ro…
(-)-Catechin gallate
(-)-Catechin gallate is an antioxidant constituent of green tea. At uM concentrations, inhibits VEGF-induced tyrosine phosphorylation.
Keywords:buy ZM 323881 hydrochloride | ZM 323881 hydrochloride Supplier | purchase | cost | manufacturer | order | distributor | buy 324077-30-7| 324077-30-7 Supplier | purchase 324077-30-7 | 324077-30-7 cost | 324077-30-7 manufacturer | order 324077-30-7 | 324077-30-7 distributor