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E-7050 (Golvatinib)

Name: E-7050 (Golvatinib)
Brand: Adooq Bioscience
SKU: A11396
Rating: 100 (268 reviews)

Catalog No.: A11396

E-7050 (Golvatinib) Chemical Structure

CAS NO. 928037-13-2

E7050 (also known as golvatinib is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity.

Availability: In stock

Package	Price	Qty
10 mg	Regular Price: $110.00 Special Price $88.00
25 mg	Regular Price: $220.00 Special Price $176.00
50 mg	Regular Price: $380.00 Special Price $304.00
100 mg	Regular Price: $680.00 Special Price $544.00
10mM * 1mL in DMSO	Regular Price: $129.00 Special Price $103.20
Custom Size	Get quote

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Products are for laboratory research use only. Not for human use. We do not sell to patients.

Adooq Products cited in reputable paper

Biological Activity

Targets

c-Met	VEGFR2
14 nM	16 nM

Solubility *

In vitro (25°C)	DMSO	18 mg/mL (28.4 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.78 mL	78.9 mL	157.81 mL
0.5 mM	3.16 mL	15.78 mL	31.56 mL
1 mM	1.58 mL	7.89 mL	15.78 mL
5 mM	0.32 mL	1.58 mL	3.16 mL

*The above data is based on the productmolecular weight 633.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A11396
CAS No.	928037-13-2
Formula	C33H37F2N7O4
M. Wt	633.69
Purity	>98%
SMILES	CN1CCN(CC1)C2CCN(CC2)C(=O)NC3=NC=CC(=C3)OC4=CC(=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.