E-7050 (Golvatinib)

Name: E-7050 (Golvatinib)
Brand: Adooq Bioscience
SKU: A11396
Rating: 100 (268 reviews)

Catalog No.: A11396

E-7050 (Golvatinib) Chemical Structure

CAS NO. 928037-13-2

E7050 (also known as golvatinib is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity.

Availability: In stock

Package	Price	Qty
10 mg	$110.00
25 mg	$220.00
50 mg	$380.00
100 mg	$680.00
10mM * 1mL in DMSO	$129.00
Custom Size	Get quote

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Biological Activity

Targets

c-Met	VEGFR2
14 nM	16 nM

Solubility *

In vitro (25°C)	DMSO	20 mg/mL (31.56 mM)
	Water	<1 mg/mL (<1 mM)
	Ethanol	<1 mg/mL (<1 mM)
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	30 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.78 mL	78.9 mL	157.81 mL
0.5 mM	3.16 mL	15.78 mL	31.56 mL
1 mM	1.58 mL	7.89 mL	15.78 mL
5 mM	0.32 mL	1.58 mL	3.16 mL

*The above data is based on the productmolecular weight 633.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A11396
M. Wt	633.69
Formula	C33H37F2N7O4
Solubility	DMSO
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	928037-13-2
SMILES	CN1CCN(CC1)C2CCN(CC2)C(=O)NC3=NC=CC(=C3)OC4=CC(=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F