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Publications citing Adooq Products
PD173074 Citations (1)
- Cheryl Q.E. Lee,et al. What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast, Stem Cell Reports, 2016, Feb 9; 6(2): 257-272 26862703
Chemical Information
| Catalog Num | A10703 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 523.7 |
| Formula | C28H41N7O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 219580-11-7 |
| Synonyms | PD-173074 |
| SMILES code | CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C |
| Chemical Name | N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea |
Description |
PD173074 is a potent, cell permeable and ATP competitive inhibitor of FGFR and VEGFR. | ||||||||||||||||
Targets |
|
||||||||||||||||
| Solubility (25°C)* | In vitro | DMSO | 100 mg/mL (190.95 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 100 mg/mL (190.95 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.09 mL | 95.47 mL | 190.95mL |
| 0.5 mM | 3.82 mL | 19.09 mL | 38.19 mL |
| 1 mM | 1.91 mL | 9.55 mL | 19.09 mL |
| 5 mM | 0.38 mL | 1.91 mL | 3.82 mL |
*The above data is based on the productmolecular weight 523.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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