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FGFR1/VEGFR2 Inhibitor

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Catalog No. A10703

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PD173074 5mg A10703-5

Regular Price: €28.50

Special Price: €25.65

PD173074 10mg A10703-10

Regular Price: €47.50

Special Price: €42.75

PD173074 50mg A10703-50

Regular Price: €133.00

Special Price: €119.70

PD173074 100mg A10703-100

Regular Price: €209.00

Special Price: €188.10

PD173074 10mM * 1mL in DMSO A10703-10mM-D

Regular Price: €47.50

Special Price: €42.75

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PD173074 is a potent, cell permeable and ATP competitive inhibitor of FGFR and VEGFR.


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Publications citing Adooq Products
PD173074 Citations (1)
  • Cheryl Q.E. Lee, .et al. What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast, Stem Cell Reports, 2016, Feb 9; 6(2): 257-272 PMID: 26862703

Chemical Information

Catalog Num A10703
Actions Inhibitor
M. Wt 523.7
Formula C28H41N7O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 219580-11-7
Synonyms PD-173074

Biological Activity

PD173074 is a potent, cell permeable and ATP competitive inhibitor of FGFR and VEGFR.
Target Value
FGFR1IC50: ~25nM
VEGFR2IC50: 100nM-200nM
c-SrcIC50: 19.8μM
EGFRIC50: >50μM
Insulin ReceptorIC50: >50μM
MEKIC50: >50μM
PKCIC50: >50μM


Solubility (25°C)* In vitro DMSO 100 mg/mL (190.95 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (190.95 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.09 mL 95.47 mL 190.95mL
0.5 mM 3.82 mL 19.09 mL 38.19 mL
1 mM 1.91 mL 9.55 mL 19.09 mL
5 mM 0.38 mL 1.91 mL 3.82 mL

*The above data is based on the productmolecular weight 523.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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