Glycosidase | Adooq Bioscience

Cat. No.: A75059

CAS No.: 2759897-35-1

Gcase activator 2

Gcase Activator 2 is a pyrrolo[2,3-b]pyrazine that serves as a potent activator of β-glucocerebrosidase (GCase), with an EC50 of 3.8 μM. This compound facilitates GCase dimerization, promoting both K-type and V-type interactions. Gcase Activator 2 displays low metabolic clearance in both human and mouse systems, making it a valuable tool for research into GCase-related biological pathways and potential therapeutic applications in lysosomal storage disorders.

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Cat. No.: A75071

CAS No.: 2270984-21-7

Gcase activator 3

GCase Activator 3 is a glucocerebrosidase (GCase) activator that enhances enzyme stability and activity. This compound effectively reduces misfolding and degradation of mutant GCase proteins in fibroblasts and dopaminergic neurons, providing a potential therapeutic strategy for conditions such as Parkinson's disease and related synucleinopathies. GCase Activator 3 is instrumental in advancing research aimed at understanding and treating these neurodegenerative disorders.

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1 mg

$210.00

5 mg

$480.00

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N-Boc-3-hydroxy-1,2,3,6-tetrahydropyridine

Cat. No.: A75095

CAS No.: 224779-27-5

N-Boc-3-hydroxy-1,2,3,6-tetrahydropyridine

N-Boc-3-hydroxy-1,2,3,6-tetrahydropyridine is a β-glucocerebrosidase activator that enhances enzyme activity by approximately 20%. This reagent is valuable for research into lysosomal storage disorders and related protein misfolding diseases, facilitating studies aimed at understanding and potentially treating these conditions.

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100 mg

$40.00

250 mg

$80.00

All 6 sizes