IRE1

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Catalog No.
Product Name
Application
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Product Citation
  1. IRE1α inhibitor

    MKC3946 is a potent and soluble IRE1α inhibitor, used for cancer research.
  2. IRE1α RNase kinase inhibitor

    KIRA6 is an advanced small-molecule IRE1α RNase kinase inhibitor with an IC50 of 0.6 ?M. KIRA6 can trigger an apoptotic response.
  3. IRE-1α inhibitor

    6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC95682) is an IRE-1α inhibitor with an IC50 of 0.08 μM, extracted from patent WO 2008154484 A1, IRE-lα inhibitor compound 3-5.
  4. IRE1 Rnase inhibitor

    4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM.
  5. IRE1α inhibitor

    APY29 inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.
  6. IRE1α inhibitor

    STF-083010 is a specific IRE1α inhibitor. STF-083010 inhibits Ire1 endonuclease activity, without affecting its kinase activity, after endoplasmic reticulum stress.
  7. mono-selective IRE1α inhibitor

    Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
  8. XBP1 inhibitor

    Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage, with an IC50 of 80 nM.
  9. IRE1 RNase inhibitor

    MKC8866, a salicylaldehyde analog, is a potent, selective IRE1 RNase inhibitor with an IC50 of 0.29?μM in human vitro.
  10. IRE-1 RNase inhibitor

    B I09 is an IRE-1 RNase inhibitor, with an IC50 of 1230 nM.
  11. Hydroxy aryl aldehydes (HAA) inhibitor

    MKC9989 is a Hydroxy aryl aldehydes (HAA) inhibitor and also inhibits IRE1α with an IC50 of 0.23 to 44 μM.
  12. IRE1α inhibitor

    Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.

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