Chelators & Bifunctional Chelators

Cat. No.

B20032

CAS No.

1105741-38-5

p-NH2-CHX-A"-DTPA

p-NH2-CHX-A"-DTPA is a bifunctional chelating agent that effectively forms stable complexes with metal ions. This compound is primarily utilized in radiolabeling applications, facilitating the attachment of radiolabeled metal ions to biomolecules for imaging and therapeutic purposes. Its ability to selectively chelate a variety of metal ions makes it a valuable tool in both in vivo and in vitro studies in the fields of medicinal chemistry and molecular imaging.

Cat. No.

B20044

CAS No.

2487415-28-9

3tBu-Crown TFA

3tBu-Crown TFA is a chelator that effectively binds radiometals, enabling the targeted delivery of these metals to biological systems. This compound can be conjugated with various targeting moieties, enhancing its application in radiopharmaceutical development. 3tBu-Crown TFA is particularly useful in cancer research, where it facilitates the investigation and development of targeted therapies involving radiometal imaging and treatment.

Cat. No.

B21369

CAS No.

85-85-8

1-(2-Pyridylazo)-2-naphthol

Synonyms: 1-Pyridylazo-2-naphthol

1-(2-Pyridylazo)-2-naphthol is an azo compound primarily functioning as a chelating agent. It exhibits significant affinity for metal ions, facilitating its use in applications such as precipitation, flocculation, and as an auxiliary complexing agent. This compound serves as an effective ligand for immobilizing on various supports, enhancing chelating properties for a wide range of chemical and biological research applications.

Cat. No.

B21384

CAS No.

95-45-4

Dimethylglyoxime

Synonyms: Biacetyl dioxime

Dimethylglyoxime is a nickel-specific chelator known for its ability to selectively bind nickel ions. This compound is particularly useful in biochemical research, where it plays a role in inhibiting or reducing the aggregation of amyloid-beta (Aβ) peptides in vitro. Its application extends to studies involving metal ion interactions and neurodegenerative disease models, making it a valuable tool for researchers investigating protein aggregation processes.

Cat. No.

B21562

CAS No.

60-00-4

Ethylenediaminetetraacetic acid

Synonyms: EDTA

Ethylenediaminetetraacetic acid (EDTA) is a metal chelator that forms stable complexes with bivalent and trivalent metal cations, including calcium. This compound exhibits various biological activities, such as antibacterial, anti-inflammatory, antioxidant, and anticoagulant effects, and is effective in reducing metal ion-catalyzed oxidative damage to proteins. EDTA is utilized in research applications related to liver fibrosis, coronary artery disease, and neurological disorders, facilitating the maintenance of a reducing environment during protein purification.