Bombesin Receptors | Adooq Bioscience

Cat. No.: A59102

CAS No.: 67338-70-9

[Tyr4]-Bombesin

[Tyr4]-Bombesin is a selective ligand for the gastrin-releasing peptide receptor (GRPR), a critical target in oncology research. This analogue of Bombesin demonstrates significant biological activity, promoting GRPR-mediated signaling pathways. It is valuable for studying tumor metabolism, neuroendocrine functions, and the role of GRPR in cancer progression. Researchers can utilize [Tyr4]-Bombesin to explore GRPR-targeted therapies and diagnostic imaging in cancer studies.

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Cat. No.: A59114

CAS No.: 81608-29-9

GRP (14-27) (human, porcine, canine)

GRP (14-27) is a bombesin receptor ligand derived from human, porcine, and canine sources. This peptide displays specific binding properties to bombesin receptors, which is inhibited by guanosine triphosphate (GTP) and guanosine diphosphate (GDP), indicating a competitive mechanism of action. GRP (14-27) is useful in research applications focused on neuropeptide signaling and receptor interactions.

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Cat. No.: A59115

CAS No.: 721937-56-0

AMBA

AMBA is a selective ligand for the gastrin-releasing peptide receptor (GRPR), exhibiting a human IC50 of 0.82 nM and a human Ki of 0.65 nM. With high affinity and specificity for GRPR, AMBA facilitates receptor-mediated endocytosis, allowing for the retention of attached radiometals within target cells. This reagent is particularly relevant in the study of prostate cancer, providing valuable insights into receptor-targeted therapies.

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