Prostanoid Receptors

Cat. No.

A63117

CAS No.

27415-25-4

8-Isoprostaglandin E2

Synonyms: iPE2-III

8-Isoprostaglandin E2 (iPE2-III) is a potent ligand for the thromboxane A2 receptor (TP). It is known to induce vasoconstriction and promote platelet aggregation, making it significant in vascular biology and hemostasis research. Additionally, 8-Isoprostaglandin E2 enhances the RANKL-dependent osteoclastic activity of marrow hematopoietic precursors through the cAMP signaling pathway, positioning it as a valuable agent in studies of bone metabolism and related disorders.

Cat. No.

A63204

CAS No.

13345-51-2

Prostaglandin B1

Synonyms: PGB1

Prostaglandin B1 (PGB1) is a metabolite of Prostaglandin E1, acting as a ligand for prostanoid receptors. It plays a significant role in various biological processes, including mediating inflammation and regulating vascular functions. PGB1 is widely used in research to explore its physiological effects and potential therapeutic applications in cardiovascular and inflammatory diseases.

Cat. No.

A63283

CAS No.

24570-01-2

11-epi-PGE1

Synonyms: 11β-Prostaglandin E1

11-epi-PGE1 (11β-Prostaglandin E1) is a prostanoid receptor ligand that serves as a less potent isomer of Prostaglandin E1. This compound is utilized in research to investigate the modulation of prostanoid signaling pathways and their associated biological effects. Its unique properties may facilitate studies in inflammation, vascular biology, and other physiological processes where prostaglandins play a crucial role.

Cat. No.

A63358

CAS No.

27930-45-6

Alprostadil sodium

Alprostadil sodium is a ligand for prostaglandin receptors, demonstrating Ki values of 36, 10, 1.1, 2.1, and 33 nM for the EP1, EP2, EP3, EP4, and IP receptors in murine models, respectively. This compound effectively promotes vasodilation and inhibits platelet aggregation, rendering it a valuable tool for research into peripheral vascular disease and its associated pathophysiology. Alprostadil sodium's vasodilatory properties make it significant for exploring therapeutic strategies in vascular disorders.

Cat. No.

A63398

CAS No.

35900-16-4

Prostaglandin E1 ethyl ester

Synonyms: Prostaglandin E1 Et ester; PGE1-EE

Prostaglandin E1 ethyl ester is a prodrug of Prostaglandin E1 (PGE1), a potent ligand for prostaglandin receptors. This compound is known for its ability to induce vasodilation and inhibit platelet aggregation, making it valuable in vascular research. It is utilized in studies related to cardiology, reproductive health, and conditions of impaired blood flow.