Thyrotropin Receptor (TSHR)

Cat. No.

A63965

CAS No.

2143452-20-2

TSHR antagonist S37a

TSHR Antagonist S37a is a selective inhibitor of the thyrotropin receptor (TSHR), demonstrating significant potential for therapeutic applications in Graves' orbitopathy. This compound effectively modulates TSHR signaling, thereby influencing thyroid hormone activity and offering insights into the pathophysiology of thyroid-related disorders. Its specificity and efficacy make it a valuable tool for research in endocrine and autoimmune disease studies.

Cat. No.

A63970

CAS No.

6336-50-1

Benzylthiouracil

Synonyms: 6-Benzyl-2-thiouracil

Benzylthiouracil is a potent inhibitor of the TSH receptor, employed primarily in the management of hyperthyroidism. By blocking the effects of thyroid-stimulating hormone, it reduces the production of thyroid hormones, thereby alleviating symptoms associated with hyperthyroidism. This compound is valuable in both clinical settings and research applications focused on thyroid function and related disorders.

Cat. No.

A63972

CAS No.

2143452-22-4

TSHR antagonist S37b

TSHR antagonist S37b is an enantiomeric compound that functions as a thyrotropin receptor (TSHR) inhibitor, exhibiting reduced efficacy compared to its counterpart, S37a. While S37b demonstrates a limited impact on TSHR inhibition, it serves as a valuable tool for investigations into thyroid function and dysregulation. This compound is suitable for research focused on the role of TSHR in thyroid-related conditions.